Human TLR4 Antibody | R&D Systems AF1478 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human TLR4 Antibody

catalog :

AF1478

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 19

Reference
Youn S, Jiang F, Won H, Hong D, Kang T, Park Y, et al. PAUF Induces Migration of Human Pancreatic Cancer Cells Exclusively via the TLR4/MyD88/NF-κB Signaling Pathway. Int J Mol Sci. 2022;23: pubmed publisher
Sugita S, Naito Y, Zhou L, He H, Hao Q, Sakamoto A, et al. Hyaluronic acid restored protein permeability across injured human lung microvascular endothelial cells. FASEB Bioadv. 2022;4:619-631 pubmed publisher
Chen B, Han J, Chen S, Xie R, Yang J, Zhou T, et al. MicroLet-7b Regulates Neutrophil Function and Dampens Neutrophilic Inflammation by Suppressing the Canonical TLR4/NF-κB Pathway. Front Immunol. 2021;12:653344 pubmed publisher
De Luccia T, Ono E, Menon R, Borbely A, Mattar R, RICHARDSON L, et al. The effect of Gestational Diabetes Mellitus on the fetal compartment. J Reprod Immunol. 2021;145:103314 pubmed publisher
Schwarz N, Tumpara S, Wrenger S, Ercetin E, Hamacher J, Welte T, et al. Alpha1-antitrypsin protects lung cancer cells from staurosporine-induced apoptosis: the role of bacterial lipopolysaccharide. Sci Rep. 2020;10:9563 pubmed publisher
Ernst E, Amoushahi M, Sørensen A, Kragstrup T, Ernst E, Lykke Hartmann K. Distinct expression patterns of TLR transcripts in human oocytes and granulosa cells from primordial and primary follicles. J Reprod Immunol. 2020;140:103125 pubmed publisher
Jun J, Lau L. CCN1 is an opsonin for bacterial clearance and a direct activator of Toll-like receptor signaling. Nat Commun. 2020;11:1242 pubmed publisher
Zheng M, Ambesi A, McKeown Longo P. Role of TLR4 Receptor Complex in the Regulation of the Innate Immune Response by Fibronectin. Cells. 2020;9: pubmed publisher
Song H, Zhou L, Liu D, Ge L, Li Y. Probiotic effect on Helicobacter pylori attachment and inhibition of inflammation in human gastric epithelial cells. Exp Ther Med. 2019;18:1551-1562 pubmed publisher
Øya E, Becher R, Ekeren L, Afanou A, Øvrevik J, Holme J. Pro-Inflammatory Responses in Human Bronchial Epithelial Cells Induced by Spores and Hyphal Fragments of Common Damp Indoor Molds. Int J Environ Res Public Health. 2019;16: pubmed publisher
Schaeffer E, Sánchez Fernández E, Gonçalves Pereira R, Flacher V, Lamon D, Duval M, et al. sp2-Iminosugar glycolipids as inhibitors of lipopolysaccharide-mediated human dendritic cell activation in vitro and of acute inflammation in mice in vivo. Eur J Med Chem. 2019;169:111-120 pubmed publisher
Song H, Tan G, Yang Y, Cui A, Li H, Li T, et al. Hepatitis B Virus-Induced Imbalance of Inflammatory and Antiviral Signaling by Differential Phosphorylation of STAT1 in Human Monocytes. J Immunol. 2019;202:2266-2275 pubmed publisher
Sootichote R, Thuwajit P, Singsuksawat E, Warnnissorn M, Yenchitsomanus P, Ithimakin S, et al. Compound A attenuates toll-like receptor 4-mediated paclitaxel resistance in breast cancer and melanoma through suppression of IL-8. BMC Cancer. 2018;18:231 pubmed publisher
Harrison S, Scambler T, Oubussad L, Wong C, Wittmann M, McDermott M, et al. Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations Results in Hyperresponsiveness to Lipopolysaccharide. Front Immunol. 2018;9:173 pubmed publisher
Ben Haij N, PlanÃ¨s R, Leghmari K, Serrero M, Delobel P, Izopet J, et al. HIV-1 Tat Protein Induces Production of Proinflammatory Cytokines by Human Dendritic Cells and Monocytes/Macrophages through Engagement of TLR4-MD2-CD14 Complex and Activation of NF-ÎºB Pathway. PLoS ONE. 2015;10:e0129425 pubmed publisher
Avlas O, Bragg A, Fuks A, Nicholson J, Farkash A, Porat E, et al. TLR4 Expression Is Associated with Left Ventricular Dysfunction in Patients Undergoing Coronary Artery Bypass Surgery. PLoS ONE. 2015;10:e0120175 pubmed publisher
Su Y, Yang J, Lee H, Sheu F, Hsu C, Lin S, et al. The C-terminal disulfide bonds of Helicobacter pylori GroES are critical for IL-8 secretion via the TLR4-dependent pathway in gastric epithelial cells. J Immunol. 2015;194:3997-4007 pubmed publisher
Vogel S, BÃ¶rger V, Peters C, FÃ¶rster M, Liebfried P, Metzger K, et al. Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death. Cell Death Differ. 2015;22:1219-30 pubmed publisher
Torgersen M, Engedal N, Pedersen A, Husebye H, Espevik T, Sandvig K. Toll-like receptor 4 facilitates binding of Shiga toxin to colon carcinoma and primary umbilical vein endothelial cells. FEMS Immunol Med Microbiol. 2011;61:63-75 pubmed publisher

product information

master code :

AF1478

SKU :

AF1478

product name :

Human TLR4 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human TLR4 Antibody from R&D Systems is a goat polyclonal antibody to TLR4. This antibody reacts with bacteria - helicobacter pylori,human,mouse. The Human TLR4 Antibody has been validated for the following applications: Immunocytochemistry,Western Blot,Neutralization,Flow Cytometry,Neutralizing,Immunoprecipitation,Functional Assay,Immunohistochemistry,Immunohistochemistry-Frozen,CyTOF-ready.

target :

TLR4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human TLR4, Glu24-Lys631, Accession # O00206

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Bacteria - Helicobacter pylori,Human,Mouse

specificity :

Detects human TLR4 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant mouse TLR4 is observed.

gene symbol :

TLR4

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

TLR4 antibody in Human Prostate by Immunohistochemistry (IHC-P).

accessionNumbers :

O00206

applications :

Neutralization,Neutralizing,Flow Cytometry,Immunoprecipitation,Western Blot,Functional Assay,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready

USD :

509 USD

alt names :

ARMD10, CD_antigen: CD284, CD284, CD284 antigen, EC 3.2.2.6, EC:3.2.2.6, homolog of Drosophila toll, hToll, TLR4, TLR-4, TOLL, toll like receptor 4 protein, toll-like receptor 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage