product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat HTRA2/Omi Antibody
catalog :
AF1458
quantity :
100 ug (also 25 ug)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 6
Reference
Wei xdf J, Heib M, Korn T, Hoyer J, Fuchslocher Chico J, Voigt S, et al. Protease-independent control of parthanatos by HtrA2/Omi. Cell Mol Life Sci. 2023;80:258 pubmed publisher
Aishwarya R, Alam S, Abdullah C, Morshed M, Nitu S, Panchatcharam M, et al. Pleiotropic effects of mdivi-1 in altering mitochondrial dynamics, respiration, and autophagy in cardiomyocytes. Redox Biol. 2020;36:101660 pubmed publisher
Szego E, Dominguez Meijide A, Gerhardt E, König A, Koss D, Li W, et al. Cytosolic Trapping of a Mitochondrial Heat Shock Protein Is an Early Pathological Event in Synucleinopathies. Cell Rep. 2019;28:65-77.e6 pubmed publisher
Packer L, Stehbens S, Bonazzi V, Gunter J, Ju R, Ward M, et al. Bcl-2 inhibitors enhance FGFR inhibitor-induced mitochondrial-dependent cell death in FGFR2-mutant endometrial cancer. Mol Oncol. 2019;13:738-756 pubmed publisher
Vincent A, Rosa H, Pabis K, Lawless C, Chen C, Grünewald A, et al. Subcellular origin of mitochondrial DNA deletions in human skeletal muscle. Ann Neurol. 2018;84:289-301 pubmed publisher
Saita S, Nolte H, Fiedler K, Kashkar H, Venne A, Zahedi R, et al. PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. Nat Cell Biol. 2017;19:318-328 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1458
SKU :
AF1458
product name :
Human/Mouse/Rat HTRA2/Omi Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat HTRA2/Omi Antibody from R&D Systems is a rabbit polyclonal antibody to HTRA2/Omi. This antibody reacts with hamster,human,mouse,rat. The Human/Mouse/Rat HTRA2/Omi Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.
target :
HTRA2/Omi
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.25 ug/mL, Simple Western 2.5 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Rabbit
immunogen :
E. coli -derived recombinant human HTRA2/Omi, Ala134-Glu458, Accession # O43464
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Hamster,Human,Mouse,Rat
specificity :
Detects human, mouse, and rat full length and mitochondria-processed HTRA2/Omi.
gene symbol :
HTRA2
top caption :
Detection of Human/Mouse/Rat HTRA2/Omi antibody by Western Blot.
accessionNumbers :
O43464
applications :
Simple Western,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
409 USD
alt names :
High temperature requirement protein A2, HtrA serine peptidase 2, HtrA2, HtrA-like serine protease, Omi, OMIOmi stress-regulated endoprotease, PARK13EC 3.4.21.108, PRSS25, PRSS25serine, 25, Serine protease 25, serine protease HTRA2, mitochondrial, Serine proteinase OMI
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.