Mouse PDGF-C Antibody | R&D Systems AF1447 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse PDGF-C Antibody

catalog :

AF1447

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 3

Reference
Opzoomer J, Anstee J, Dean I, Hill E, Bouybayoune I, Caron J, et al. Macrophages orchestrate the expansion of a proangiogenic perivascular niche during cancer progression. Sci Adv. 2021;7:eabg9518 pubmed publisher
Hu W, Zhang R, Chen W, Lin D, Wei K, Li J, et al. Glycosylation at Asn254 Is Required for the Activation of the PDGF-C Protein. Front Mol Biosci. 2021;8:665552 pubmed publisher
Zheng L, Zhao C, Du Y, Lin X, Jiang Y, Lee C, et al. PDGF-CC underlies resistance to VEGF-A inhibition and combinatorial targeting of both suppresses pathological angiogenesis more efficiently. Oncotarget. 2016;7:77902-77915 pubmed publisher

product information

brand :

R&D Systems

master code :

AF1447

SKU :

AF1447

product name :

Mouse PDGF-C Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Mouse PDGF-C Antibody from R&D Systems is a goat polyclonal antibody to PDGF-C. This antibody reacts with mouse,rat. The Mouse PDGF-C Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,In vivo assay.

target :

PDGF-C

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 4-16 ug/mL

host :

Goat

immunogen :

E. coli -derived recombinant mouse PDGF-CC, Val235-Gly345, Accession # Q8CI19

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Rat

specificity :

Detects mouse PDGF-C in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant human (rh) PDGF-CC is observed and less than 1% cross-reactivity with rhPDGF-AA, rhPDGF-BB, rhPDGF-D, and recombinant rat PDGF-AB is observed.

gene symbol :

PDGFC

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

Q8CI19

applications :

Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,In vivo assay,Neutralization

USD :

479 USD

alt names :

FALLOTEIN, PDGFC, PDGF-C, platelet derived growth factor C, platelet-derived growth factor C, SCDGFSpinal cord-derived growth factor, secretory growth factor-like protein, VEGF-E

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage