product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse/Rat FABP4/A-FABP Antibody
catalog :
AF1443
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, western blot knockout validation
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; mouse; 0.25 ug/ml; loading ...; fig 1b, 5b
  • immunohistochemistry - frozen section; mouse; 5 ug/ml; loading ...; fig 2a
  • immunohistochemistry - paraffin section; mouse; 5 ug/ml; loading ...; fig 2a
  • western blot; human; 0.25 ug/ml; loading ...; fig 3c, 3f
Wu X, Shu L, Zhang Z, Li J, Zong J, Cheong L, et al. Adipocyte Fatty Acid Binding Protein Promotes the Onset and Progression of Liver Fibrosis via Mediating the Crosstalk between Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells. Adv Sci (Weinh). 2021;8:e2003721 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2f
Xiao Y, Shu L, Wu X, Liu Y, Cheong L, Liao B, et al. Fatty acid binding protein 4 promotes autoimmune diabetes by recruitment and activation of pancreatic islet macrophages. JCI Insight. 2021;6: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 10 ug/ml; loading ...; fig 3d, 4b
Bando Y, Tokuda N, Ogasawara Y, Onozawa G, Nagasaka A, Sakiyama K, et al. Expression and enhancement of FABP4 in septoclasts of the growth plate in FABP5-deficient mouse tibiae. Histochem Cell Biol. 2021;155:439-449 pubmed publisher
Plumber S, Tate T, Al Ahmadie H, Chen X, Choi W, Başar M, et al. Rosiglitazone and trametinib exhibit potent anti-tumor activity in a mouse model of muscle invasive bladder cancer. Nat Commun. 2024;15:6538 pubmed publisher
Kang Y, Yeo M, Derman İ, Ravnic D, Singh Y, Alioglu M, et al. Intraoperative bioprinting of human adipose-derived stem cells and extra-cellular matrix induces hair follicle-like downgrowths and adipose tissue formation during full-thickness craniomaxillofacial skin reconstruction. Bioact Mater. 2024;33:114-128 pubmed publisher
Kang Y, Yeo M, Derman İ, Ravnic D, Singh Y, Alioglu M, et al. Intraoperative Bioprinting of Human Adipose-derived Stem cells and Extra-cellular Matrix Induces Hair Follicle-Like Downgrowths and Adipose Tissue Formation during Full-thickness Craniomaxillofacial Skin Reconstruction. bioRxiv. 2023;: pubmed publisher
Tate T, Plumber S, Al Ahmadie H, Chen X, Choi W, Lu C, et al. Combined Mek inhibition and Pparg activation Eradicates Muscle Invasive Bladder cancer in a Mouse Model of BBN-induced Carcinogenesis. bioRxiv. 2023;: pubmed publisher
James J, Dekan A, Niihori M, McClain N, Varghese M, Bharti D, et al. Novel Populations of Lung Capillary Endothelial Cells and Their Functional Significance. Res Sq. 2023;: pubmed publisher
Zioni N, Bercovich A, Chapal Ilani N, Bacharach T, Rappoport N, Solomon A, et al. Inflammatory signals from fatty bone marrow support DNMT3A driven clonal hematopoiesis. Nat Commun. 2023;14:2070 pubmed publisher
Ahn J, Suh Y, Lee K. Chordin-like 1, a Novel Adipokine, Markedly Promotes Adipogenesis and Lipid Accumulation. Cells. 2023;12: pubmed publisher
Bahrami Nejad Z, Zhang Z, Tholen S, Sharma S, Rabiee A, Zhao M, et al. Early enforcement of cell identity by a functional component of the terminally differentiated state. PLoS Biol. 2022;20:e3001900 pubmed publisher
Zhang Z, Sinha J, Bahrami Nejad Z, Teruel M. The circadian clock mediates daily bursts of cell differentiation by periodically restricting cell-differentiation commitment. Proc Natl Acad Sci U S A. 2022;119:e2204470119 pubmed publisher
Sa xe7 ma M, Matteini F, Mulaw M, Hageb A, Bogeska R, Sakk V, et al. Fast and high-fidelity in situ 3D imaging protocol for stem cells and niche components for mouse organs and tissues. STAR Protoc. 2022;3:101483 pubmed publisher
Li Z, Bowers E, Zhu J, Yu H, Hardij J, Bagchi D, et al. Lipolysis of bone marrow adipocytes is required to fuel bone and the marrow niche during energy deficits. elife. 2022;11: pubmed publisher
Sathyanarayana A, Lu C, Liaw C, Chang C, Han H, Green B, et al. 1,2,3,4,6-Penta-O-galloyl-d-glucose Interrupts the Early Adipocyte Lifecycle and Attenuates Adiposity and Hepatic Steatosis in Mice with Diet-Induced Obesity. Int J Mol Sci. 2022;23: pubmed publisher
Heydt Q, Xintaropoulou C, Clear A, Austin M, Pislariu I, Miraki Moud F, et al. Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence. Nat Commun. 2021;12:5507 pubmed publisher
Guan H, Zheng H, Zhang J, Xiang A, Li Y, Zheng H, et al. Secreted frizzled-related protein 4 promotes brown adipocyte differentiation. Exp Ther Med. 2021;21:637 pubmed publisher
Abbasi S, Sinha S, Labit E, Rosin N, Yoon G, Rahmani W, et al. Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing. Cell Stem Cell. 2020;27:396-412.e6 pubmed publisher
Valet C, Batut A, Vauclard A, Dortignac A, Bellio M, Payrastre B, et al. Adipocyte Fatty Acid Transfer Supports Megakaryocyte Maturation. Cell Rep. 2020;32:107875 pubmed publisher
Zhao M, Rabiee A, Kovary K, Bahrami Nejad Z, Taylor B, Teruel M. Molecular Competition in G1 Controls When Cells Simultaneously Commit to Terminally Differentiate and Exit the Cell Cycle. Cell Rep. 2020;31:107769 pubmed publisher
Sacma M, Pospiech J, Bogeska R, de Back W, Mallm J, Sakk V, et al. Haematopoietic stem cells in perisinusoidal niches are protected from ageing. Nat Cell Biol. 2019;21:1309-1320 pubmed publisher
Liu C, Tate T, Batourina E, Truschel S, POTTER S, Adam M, et al. Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells. Nat Commun. 2019;10:4589 pubmed publisher
Miceli V, Pampalone M, Vella S, Carreca A, Amico G, Conaldi P. Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems. Stem Cells Int. 2019;2019:7486279 pubmed publisher
Guerrero Juarez C, Dedhia P, Jin S, Ruiz Vega R, Ma D, Liu Y, et al. Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds. Nat Commun. 2019;10:650 pubmed publisher
Yee C, Zheng Z, Shuman L, Yamashita H, Warrick J, Wu X, et al. Maintenance of the bladder cancer precursor urothelial hyperplasia requires FOXA1 and persistent expression of oncogenic HRAS. Sci Rep. 2019;9:270 pubmed publisher
Shu L, Hoo R, Wu X, Pan Y, Lee I, Cheong L, et al. A-FABP mediates adaptive thermogenesis by promoting intracellular activation of thyroid hormones in brown adipocytes. Nat Commun. 2017;8:14147 pubmed publisher
Myers C, Hoelzinger D, Truong T, Chew L, Myles A, Chaudhuri L, et al. Chemotherapy can induce weight normalization of morbidly obese mice despite undiminished ingestion of high fat diet. Oncotarget. 2017;8:5426-5438 pubmed publisher
Guo W, Chen J, Yang Y, Zhu J, Wu J. Epigenetic programming of Dnmt3a mediated by AP2α is required for granting preadipocyte the ability to differentiate. Cell Death Dis. 2016;7:e2496 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1443
SKU :
AF1443
product name :
Mouse/Rat FABP4/A-FABP Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse/Rat FABP4/A-FABP Antibody from R&D Systems is a goat polyclonal antibody to FABP4/A-FABP. This antibody reacts with human,mouse,rat,transgenic mouse,xenograft. The Mouse/Rat FABP4/A-FABP Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry/ Immunofluorescence,Simple Western.
target :
FABP4/A-FABP
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.25 ug/mL, Simple Western 2.5 ug/mL, Immunohistochemistry 5-15 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant mouse FABP4, Met1-Ala132, Accession # P04117
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse,Xenograft
specificity :
Detects mouse FABP4 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant mouse (rm) FABP5 and rmFABP9 is observed.
gene symbol :
FABP4
top caption :
Detection of Mouse FABP4/A-FABP antibody by Western Blot.
accessionNumbers :
P04117
applications :
Simple Western,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Immunocytochemistry/ Immunofluorescence
USD :
509 USD
alt names :
Adipocyte lipid-binding protein, Adipocyte-type fatty acid-binding protein, AFABP, A-FABP, A-FABPAFABP, ALBP, aP2, fatty acid binding protein 4, adipocyte, Fatty acid-binding protein 4, fatty acid-binding protein, adipocyte
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.