product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Decorin Antibody
catalog :
AF143
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 15
Reference
Yang F, Akhtar M, Zhang D, El Mayta R, Shin J, Dorsey J, et al. An immunosuppressive vascular niche drives macrophage polarization and immunotherapy resistance in glioblastoma. Sci Adv. 2024;10:eadj4678 pubmed publisher
Blanco Elices C, Morales xc1 lvarez C, Chato Astrain J, Gonz xe1 lez Gallardo C, xc1 vila Fern xe1 ndez P, Campos F, et al. Development of stromal differentiation patterns in heterotypical models of artificial corneas generated by tissue engineering. Front Bioeng Biotechnol. 2023;11:1124995 pubmed publisher
Knight Schrijver V, Davaapil H, Bayraktar S, Ross A, Kanemaru K, Cranley J, et al. A single-cell comparison of adult and fetal human epicardium defines the age-associated changes in epicardial activity. Nat Cardiovasc Res. 2022;1:1215-1229 pubmed publisher
Courrol D, da Silva C, Prado L, Chura Chambi R, Morganti L, de Souza G, et al. Leptolysin, a Leptospira secreted metalloprotease of the pappalysin family with broad-spectrum activity. Front Cell Infect Microbiol. 2022;12:966370 pubmed publisher
Basak D, Jamal Z, Ghosh A, Mondal P, Dey Talukdar P, Ghosh S, et al. Reciprocal interplay between asporin and decorin: Implications in gastric cancer prognosis. PLoS ONE. 2021;16:e0255915 pubmed publisher
Liu C, Wu B, Ho Y, Chu Y, Hsu W, Tseng T, et al. CHPF Regulates the Aggressive Phenotypes of Hepatocellular Carcinoma Cells via the Modulation of the Decorin and TGF-β Pathways. Cancers (Basel). 2021;13: pubmed publisher
Asega A, Menezes M, Trevisan Silva D, Cajado Carvalho D, Bertholim L, Oliveira A, et al. Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases. Sci Rep. 2020;10:12912 pubmed publisher
Lesaffer B, Verboven E, Van Huffel L, Moya I, van Grunsven L, Leclercq I, et al. Comparison of the Opn-CreER and Ck19-CreER Drivers in Bile Ducts of Normal and Injured Mouse Livers. Cells. 2019;8: pubmed publisher
Svärd J, Røst T, Sommervoll C, Haugen C, Gudbrandsen O, Mellgren A, et al. Absence of the proteoglycan decorin reduces glucose tolerance in overfed male mice. Sci Rep. 2019;9:4614 pubmed publisher
Kolb A, Shupp A, Mukhopadhyay D, Marini F, Bussard K. Osteoblasts are "educated" by crosstalk with metastatic breast cancer cells in the bone tumor microenvironment. Breast Cancer Res. 2019;21:31 pubmed publisher
Goncalves M, Wu Y, Clarke E, Grist J, Hobbs C, Trigo D, et al. Regulation of Myelination by Exosome Associated Retinoic Acid Release from NG2-Positive Cells. J Neurosci. 2019;39:3013-3027 pubmed publisher
Menon R, Otto E, Kokoruda A, Zhou J, Zhang Z, Yoon E, et al. Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney. Development. 2018;145: pubmed publisher
Yoon A, Hong J, Yun C. Adenovirus-mediated decorin expression induces cancer cell death through activation of p53 and mitochondrial apoptosis. Oncotarget. 2017;8:76666-76685 pubmed publisher
Perdu S, Castellana B, Kim Y, Chan K, DeLuca L, Beristain A. Maternal obesity drives functional alterations in uterine NK cells. JCI Insight. 2016;1:e85560 pubmed publisher
Reine T, Jenssen T, Kolset S. Glucosamine exposure reduces proteoglycan synthesis in primary human endothelial cells in vitro. Food Nutr Res. 2016;60:32615 pubmed publisher
product information
master code :
AF143
SKU :
AF143
product name :
Human Decorin Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Decorin Antibody from R&D Systems is a goat polyclonal antibody to Decorin. This antibody reacts with bovine,hamster,human,mouse,rat. The Human Decorin Antibody has been validated for the following applications: Immunohistochemistry,Co-IP,ELISA Development,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.
target :
Decorin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human Decorin, Gly17-Lys359, Accession # P07585
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Bovine,Hamster,Human,Mouse,Rat
specificity :
Detects human Decorin in direct ELISAs and Western blots.
gene symbol :
DCN
top caption :
Detection of Human Decorin antibody by Western Blot.
accessionNumbers :
P07585
applications :
Immunohistochemistry,Co-IP,ELISA Development,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western
USD :
479 USD
alt names :
Bone proteoglycan II, CSCD, DCN, decorin, decorin proteoglycan, dermatan sulphate proteoglycans II, DSPG2, PG40, PGII, PG-II, PGS2, PG-S2, proteoglycan core protein, SLRR1B, SLRR1BPGS2, small leucine-rich protein 1B
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.