product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse B7-H3 Antibody
catalog :
AF1397
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, neutralization
more info or order :
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; fig 2c
Picarda E, Galbo P, Zong H, Rajan M, Wallenius V, Zheng D, et al. The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development. Sci Adv. 2022;8:eabm7012 pubmed publisher
Liu H, Du H, Khabibullin D, Zarei M, Wei K, Freeman G, et al. mTORC1 upregulates B7-H3/CD276 to inhibit antitumor T cells and drive tumor immune evasion. Nat Commun. 2023;14:1214 pubmed publisher
product information
master code :
AF1397
SKU :
AF1397
product name :
Mouse B7-H3 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse B7-H3 Antibody from R&D Systems is a goat polyclonal antibody to B7-H3/CD276. This antibody reacts with mouse. The Mouse B7-H3 Antibody has been validated for the following applications: Western Blot,Neutralization.
target :
B7-H3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse B7-H3, Val29-Phe244, Accession # Q8VE98
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse B7-H3 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human (rh) B7-H3 is observed, and less than 1% cross-reactivity with recombinant mouse (rm) B7-H1, rmB7-H2 and rmB7-1 is observed.
gene symbol :
CD276
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Mouse B7-H3 antibody by Western Blot.
accessionNumbers :
Q8VE98
applications :
Western Blot,Neutralization
USD :
479 USD
alt names :
B7H3, B7H34Ig-B7-H3, B7-H3B7 homolog 3, CD276, CD276 antigen, CD276 molecule, Costimulatory molecule
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.