product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat JNK Pan Specific Antibody
catalog :
AF1387
quantity :
100 ug (also 25 ug)
price :
409 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
citations: 10
Reference
Hiraide S, Machida T, Takihana S, Ohshita M, Iizuka K. Pressure stress delays cyclooxygenase-2 expression induced by interleukin-1β in cultured human pulmonary artery smooth muscle cells. Heliyon. 2023;9:e21008 pubmed publisher
Xia Q, Mao M, Zhan G, Luo Z, Zhao Y, Li X. SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury. iScience. 2023;26:106953 pubmed publisher
Liou G, Fleming Martinez A, D xf6 ppler H, Bastea L, Storz P. Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth. iScience. 2023;26:106820 pubmed publisher
Alors Pérez E, Bl xe1 zquez Encinas R, Alcal xe1 S, Viyuela Garc xed a C, Pedraza Arevalo S, Herrero Aguayo V, et al. Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug. J Exp Clin Cancer Res. 2021;40:382 pubmed publisher
Aguado J, Chaggar H, Gómez Inclán C, Shaker M, Leeson H, Mackay Sim A, et al. Inhibition of the cGAS-STING pathway ameliorates the premature senescence hallmarks of Ataxia-Telangiectasia brain organoids. Aging Cell. 2021;20:e13468 pubmed publisher
Falero Perez J, Sheibani N, Sorenson C. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells. PLoS ONE. 2020;15:e0232779 pubmed publisher
Jiménez Vacas J, Herrero Aguayo V, Montero Hidalgo A, Gómez Gómez E, Fuentes Fayos A, León González A, et al. Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer. EBioMedicine. 2020;51:102547 pubmed publisher
Barutcu S, Girnius N, Vernia S, Davis R. Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy. Autophagy. 2018;14:1586-1595 pubmed publisher
Girnius N, Davis R. JNK Promotes Epithelial Cell Anoikis by Transcriptional and Post-translational Regulation of BH3-Only Proteins. Cell Rep. 2017;21:1910-1921 pubmed publisher
Courtial L, Picco V, Grover R, Cormerais Y, Rottier C, Labbe A, et al. The c-Jun N-terminal kinase prevents oxidative stress induced by UV and thermal stresses in corals and human cells. Sci Rep. 2017;7:45713 pubmed publisher
product information
master code :
AF1387
SKU :
AF1387
product name :
Human/Mouse/Rat JNK Pan Specific Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat JNK Pan Specific Antibody from R&D Systems is a rabbit polyclonal antibody to JNK1/2/3. This antibody reacts with human,mouse,rat,transgenic mouse,coral - stylophora pistillata (hood coral). The Human/Mouse/Rat JNK Pan Specific Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Simple Western.
target :
JNK
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rabbit
immunogen :
E. coli -derived recombinant human JNK1, Met1-Gln384, Accession # P45983
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse,Coral - Stylophora pistillata (Hood Coral)
specificity :
Detects human, mouse, and rat p46 and p54 JNK in Western blots. Detects recombinant human (rh) JNK1, rhJNK2, and rhJNK3.
gene symbol :
MAPK8IP3
top caption :
Detection of Human/Mouse/Rat JNK antibody by Western Blot.
accessionNumbers :
P45983
applications :
Western Blot,Immunohistochemistry,Simple Western
USD :
409 USD
alt names :
c-Jun N-terminal kinase 1, EC 2.7.11, EC 2.7.11.24, JNK1 alpha protein kinase, JNK1 beta protein kinase, JNK1JNK1A2, JNK-46, JUN N-terminal kinase, MAP kinase 8, MAPK 8, MAPK10, MAPK8, MAPK9, mitogen-activated protein kinase 8, mitogen-activated protein kinase 8 isoform JNK1 alpha1, mitogen-activated protein kinase 8 isoform JNK1 beta2, PRKM8, PRKM8JNK, protein kinase JNK1, SAPK1, SAPK1 alpha, SAPK1 beta, SAPK1JNK21B1/2, Stress-activated protein kinase 1, Stress-activated protein kinase JNK1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.