Human/Mouse/Rat p53 Antibody | R&D Systems AF1355 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat p53 Antibody

catalog :

AF1355

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:2000; fig 6f	Plácido L, Romero Y, Maldonado M, Toscano Marquez F, Ramirez R, Calyeca J, et al. Loss of MT1-MMP in Alveolar Epithelial Cells Exacerbates Pulmonary Fibrosis. Int J Mol Sci. 2021;22: pubmed publisher
	Oppezzo A, Monney L, Kilian H, Slimani L, Maczkowiak Chartois F, Rosselli F. Fanca deficiency is associated with alterations in osteoclastogenesis that are rescued by TNFα. Cell Biosci. 2023;13:115 pubmed publisher
	Matsumoto C, Sekine H, Zhang N, Mogami S, Fujitsuka N, Takeda H. Role of p53 in Cisplatin-Induced Myotube Atrophy. Int J Mol Sci. 2023;24: pubmed publisher
	Nakayama T, Sunaoshi M, Shang Y, Takahashi M, Saito T, Blyth B, et al. Calorie restriction alters the mechanisms of radiation-induced mouse thymic lymphomagenesis. PLoS ONE. 2023;18:e0280560 pubmed publisher
	Filippone M, Freddi S, Zecchini S, Restelli S, Colaluca I, Bertalot G, et al. Aberrant phosphorylation inactivates Numb in breast cancer causing expansion of the stem cell pool. J Cell Biol. 2022;221: pubmed publisher
	Czarnek M, Sarad K, Karaś A, Kochan J, Bereta J. Non-targeting control for MISSION shRNA library silences SNRPD3 leading to cell death or permanent growth arrest. Mol Ther Nucleic Acids. 2021;26:711-731 pubmed publisher
	Haberl E, Pohl R, Rein Fischboeck L, Höring M, Krautbauer S, Liebisch G, et al. Accumulation of cholesterol, triglycerides and ceramides in hepatocellular carcinomas of diethylnitrosamine injected mice. Lipids Health Dis. 2021;20:135 pubmed publisher
	Rodriguez A, Zhang K, Färkkilä A, Filiatrault J, Yang C, Velázquez M, et al. MYC Promotes Bone Marrow Stem Cell Dysfunction in Fanconi Anemia. Cell Stem Cell. 2021;28:33-47.e8 pubmed publisher
	Xie B, H xe4 nsel J, Mundorf V, Betz J, Reimche I, Erkan M, et al. Pseudopterosin and O-Methyltylophorinidine Suppress Cell Growth in a 3D Spheroid Co-Culture Model of Pancreatic Ductal Adenocarcinoma. Bioengineering (Basel). 2020;7: pubmed publisher
	Toufektchan E, Lejour V, Durand R, Giri N, Draskovic I, Bardot B, et al. Germline mutation of MDM4, a major p53 regulator, in a familial syndrome of defective telomere maintenance. Sci Adv. 2020;6:eaay3511 pubmed publisher
	Besztercei B, Vancsik T, Benedek A, Major E, Thomas M, Schvarcz C, et al. Stress-Induced, p53-Mediated Tumor Growth Inhibition of Melanoma by Modulated Electrohyperthermia in Mouse Models without Major Immunogenic Effects. Int J Mol Sci. 2019;20: pubmed publisher
	Vancsik T, Forika G, Balogh A, Kiss E, Krenacs T. Modulated electro-hyperthermia induced p53 driven apoptosis and cell cycle arrest additively support doxorubicin chemotherapy of colorectal cancer in vitro. Cancer Med. 2019;8:4292-4303 pubmed publisher
	You Z, Yu M, Zhang Y, Shi K. Progranulin protects the mouse retina under hypoxic conditions via inhibition of the Toll‑like receptor‑4‑NADPH oxidase 4 signaling pathway. Mol Med Rep. 2019;19:382-390 pubmed publisher
	Wang J, He G, Yang Q, Bai L, Jian B, Li Q, et al. B-cell lymphoma 2 is associated with advanced tumor grade and clinical stage, and reduced overall survival in young Chinese patients with colorectal carcinoma. Oncol Lett. 2018;15:9009-9016 pubmed publisher
	Conde M, Michen S, Wiedemuth R, Klink B, Schrock E, Schackert G, et al. Chromosomal instability induced by increased BIRC5/Survivin levels affects tumorigenicity of glioma cells. BMC Cancer. 2017;17:889 pubmed publisher
	Lessel D, Wu D, Trujillo C, Ramezani T, Lessel I, Alwasiyah M, et al. Dysfunction of the MDM2/p53 axis is linked to premature aging. J Clin Invest. 2017;127:3598-3608 pubmed publisher
	Van Roosbroeck K, Fanini F, Setoyama T, Ivan C, Rodriguez Aguayo C, Fuentes Mattei E, et al. Combining Anti-Mir-155 with Chemotherapy for the Treatment of Lung Cancers. Clin Cancer Res. 2017;23:2891-2904 pubmed publisher
	Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher

product information

brand :

R&D Systems

master code :

AF1355

SKU :

AF1355

product name :

Human/Mouse/Rat p53 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Rat p53 Antibody from R&D Systems is a goat polyclonal antibody to p53. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat p53 Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Simple Western,Immunohistochemistry-Paraffin,Immunoprecipitation,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry,Knockout Validated.

target :

p53

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.25 ug/mL, Simple Western 2.5 ug/mL, Immunoprecipitation 1-2 ug/500 ug cell lysate, Chromatin Immunoprecipitation (ChIP) 5 ug/5 x 10^6 cells, Immunocytochemistry 5-15 ug/mL, Knockout Validated

host :

Goat

immunogen :

E. coli -derived recombinant human p53, Asp7-Asp393, Accession # P04637

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human, mouse, and rat p53.

gene symbol :

TP53

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human p53 antibody by Western Blot.

accessionNumbers :

P04637

applications :

Immunoprecipitation,Chromatin Immunoprecipitation (ChIP),Immunocytochemistry,Knockout Validated,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Simple Western

USD :

489 USD

alt names :

Antigen NY-CO-13, BCC7, FLJ92943, LFS1, LFS1TRP53, p53, p53 tumor suppressor, P53cellular tumor antigen p53, Phosphoprotein p53, TP53, transformation-related protein 53, TRP53, tumor protein p53, Tumor suppressor p53

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage