Human Fc gamma RII/CD32 Antibody | R&D Systems AF1330 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Fc gamma RII/CD32 Antibody

catalog :

AF1330

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, rhesus macaque

application :

western blot, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Grunst M, Grandea A, Janaka S, Hammad I, Grimes P, Karl J, et al. Functional Interactions of Common Allotypes of Rhesus Macaque FcγR2A and FcγR3A with Human and Macaque IgG Subclasses. J Immunol. 2020;205:3319-3332 pubmed publisher
Lemke Miltner C, Blackwell S, Yin C, Krug A, Morris A, Krieg A, et al. Antibody Opsonization of a TLR9 Agonist-Containing Virus-like Particle Enhances In Situ Immunization. J Immunol. 2020;204:1386-1394 pubmed publisher
Pandruvada S, Ebersole J, Huja S. Inhibition of osteoclastogenesis by opsonized Porphyromonas gingivalis. FASEB Bioadv. 2019;1:213-226 pubmed publisher
Kuzmina N, Younan P, Gilchuk P, Santos R, Flyak A, Ilinykh P, et al. Antibody-Dependent Enhancement of Ebola Virus Infection by Human Antibodies Isolated from Survivors. Cell Rep. 2018;24:1802-1815.e5 pubmed publisher
Qureshi O, Rowley T, Junker F, Peters S, Crilly S, Compson J, et al. Multivalent Fcγ-receptor engagement by a hexameric Fc-fusion protein triggers Fcγ-receptor internalisation and modulation of Fcγ-receptor functions. Sci Rep. 2017;7:17049 pubmed publisher
McWilliams E, Mele J, Cheney C, Timmerman E, Fiazuddin F, Strattan E, et al. Therapeutic CD94/NKG2A blockade improves natural killer cell dysfunction in chronic lymphocytic leukemia. Oncoimmunology. 2016;5:e1226720 pubmed

product information

brand :

R&D Systems

master code :

AF1330

SKU :

AF1330

product name :

Human Fc gamma RII/CD32 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human Fc gamma RII/CD32 Antibody from R&D Systems is a goat polyclonal antibody to Fc gamma RII/CD32. This antibody reacts with human,primate - macaca mulatta (rhesus macaque). The Human Fc gamma RII/CD32 Antibody has been validated for the following applications: Western Blot,Blocking,Flow Cytometry,Neutralization,Immunocytochemistry,Blockade of Receptor-ligand Interaction,CyTOF-ready.

target :

Fc gamma RII/CD32

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, Blockade of Receptor-ligand Interaction, Immunocytochemistry 5-15 ug/mL, CyTOF-ready

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Fc gamma RII/CD32, Ala46-Pro217, Accession # P31994

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Primate - Macaca mulatta (Rhesus Macaque)

specificity :

Detects human Fc gamma RII/CD32 in direct ELISAs and Western blots.

gene symbol :

FCGR2A

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Fc? RII/CD32 antibody in Human PBMCs by Immunocytochemistry (ICC).

accessionNumbers :

P31994

applications :

Blockade of Receptor-ligand Interaction,CyTOF-ready,Blocking,Flow Cytometry,Western Blot,Neutralization,Immunocytochemistry

USD :

489 USD

alt names :

CD32 antigen, CD32B, CD32Fc fragment of IgG, low affinity II, receptor for (CD32), CDw32, Fc fragment of IgG, low affinity IIb, receptor (CD32), Fc fragment of IgG, low affinity IIb, receptor for (CD32), Fc gamma RIIb, FCG2, Fc-gamma RII-b, fc-gamma-RIIb, FcgammaRIIb, FCGR2, FcgRII, FcgRIIB, fcRII-b, FcRII-c, IGFR2, IgG Fc receptor II-b, low affinity immunoglobulin gamma Fc region receptor II-b

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage