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company name :
R&D Systems
product type :
antibody
product name :
Mouse Endoglin/CD105 Antibody
catalog :
AF1320
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 27
Reference
Shabani Z, Do Prado L, Zhang R, Zhu W, Shaligram S, Yadav A, et al. Increasing Endoglin Deletion in Endothelial Cells Exacerbates the Severity of Brain Arteriovenous Malformation in Mouse. Biomedicines. 2024;12: pubmed publisher
Callewaert B, Gsell W, Himmelreich U, Jones E. Q-VAT: Quantitative Vascular Analysis Tool. Front Cardiovasc Med. 2023;10:1147462 pubmed publisher
Lee S, Toft N, Axelsen T, Espejo M, Pedersen T, Mele M, et al. Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer. Breast Cancer Res. 2023;25:46 pubmed publisher
Paul M, Chakraborty S, Islam S, Ain R. Trans-differentiation of trophoblast stem cells: implications in placental biology. Life Sci Alliance. 2023;6: pubmed publisher
Erices J, Niechi I, Uribe Ojeda A, Toro M, Garc xed a Romero N, Carri xf3 n Navarro J, et al. The low affinity A2B adenosine receptor enhances migratory and invasive capacity in vitro and angiogenesis in vivo of glioblastoma stem-like cells. Front Oncol. 2022;12:969993 pubmed publisher
Magalhães Novais S, Blecha J, Naraine R, Mikešová J, Abaffy P, Pecinova A, et al. Mitochondrial respiration supports autophagy to provide stress resistance during quiescence. Autophagy. 2022;:1-18 pubmed publisher
Videira R, Koop A, Ottaviani L, Poels E, Kocken J, dos Remedios C, et al. The adult heart requires baseline expression of the transcription factor Hand2 to withstand right ventricular pressure overload. Cardiovasc Res. 2022;118:2688-2702 pubmed publisher
Kalisch Smith J, Morris E, Strevens M, Redpath A, Klaourakis K, Szumska D, et al. Analysis of Placental Arteriovenous Formation Reveals New Insights Into Embryos With Congenital Heart Defects. Front Genet. 2021;12:806136 pubmed publisher
Mar xed n Llera J, Lorda Diez C, Hurle J, Chimal Monroy J. SCA-1/Ly6A Mesodermal Skeletal Progenitor Subpopulations Reveal Differential Commitment of Early Limb Bud Cells. Front Cell Dev Biol. 2021;9:656999 pubmed publisher
Morgani S, Su J, Nichols J, Massague J, Hadjantonakis A. The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos. elife. 2021;10: pubmed publisher
Garc xed a Cervera A, Chimal Monroy J, Mar xed n Llera J. The spatiotemporal expression patterns of MSC-associated markers contribute to the identification of progenitor subpopulations in developing limbs. Int J Dev Biol. 2020;64:499-506 pubmed publisher
Chen J, Lippo L, Labella R, Tan S, Marsden B, Dustin M, et al. Decreased blood vessel density and endothelial cell subset dynamics during ageing of the endocrine system. EMBO J. 2021;40:e105242 pubmed publisher
Garcia Romero N, Palacín Aliana I, Madurga R, Carrión Navarro J, Esteban Rubio S, Jimenez B, et al. Bevacizumab dose adjustment to improve clinical outcomes of glioblastoma. BMC Med. 2020;18:142 pubmed publisher
Yoon Y, Voloudakis G, Doran N, Zhang E, Dimovasili C, Chen L, et al. PS1 FAD mutants decrease ephrinB2-regulated angiogenic functions, ischemia-induced brain neovascularization and neuronal survival. Mol Psychiatry. 2021;26:1996-2012 pubmed publisher
Chen P, Qin L, Li G, Malagon Lopez J, Wang Z, Bergaya S, et al. Smooth Muscle Cell Reprogramming in Aortic Aneurysms. Cell Stem Cell. 2020;26:542-557.e11 pubmed publisher
He D, Tang X, Dong W, Cui G, Peng G, Yin X, et al. C-KIT Expression Distinguishes Fetal from Postnatal Skeletal Progenitors. Stem Cell Reports. 2020;14:614-630 pubmed publisher
Jacob F, Salinas R, Zhang D, Nguyen P, Schnoll J, Wong S, et al. A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity. Cell. 2020;180:188-204.e22 pubmed publisher
Dumas S, Meta E, Borri M, Goveia J, Rohlenova K, Conchinha N, et al. Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation. J Am Soc Nephrol. 2020;31:118-138 pubmed publisher
Meurer S, Wimmer A, Leur E, Weiskirchen R. Endoglin Trafficking/Exosomal Targeting in Liver Cells Depends on N-Glycosylation. Cells. 2019;8: pubmed publisher
Ishikawa M, Osaki M, Yamagishi M, Onuma K, Ito H, Okada F, et al. Correlation of two distinct metastasis-associated proteins, MTA1 and S100A4, in angiogenesis for promoting tumor growth. Oncogene. 2019;38:4715-4728 pubmed publisher
Eelen G, Dubois C, Cantelmo A, Goveia J, Bruning U, DeRan M, et al. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature. 2018;561:63-69 pubmed publisher
Bauer R, Udonta F, Wroblewski M, Ben Batalla I, Santos I, Taverna F, et al. Blockade of Myeloid-Derived Suppressor Cell Expansion with All-Trans Retinoic Acid Increases the Efficacy of Antiangiogenic Therapy. Cancer Res. 2018;78:3220-3232 pubmed publisher
Coutu D, Kokkaliaris K, Kunz L, Schroeder T. Multicolor quantitative confocal imaging cytometry. Nat Methods. 2018;15:39-46 pubmed publisher
Wroblewski M, Bauer R, Cubas Córdova M, Udonta F, Ben Batalla I, Legler K, et al. Mast cells decrease efficacy of anti-angiogenic therapy by secreting matrix-degrading granzyme B. Nat Commun. 2017;8:269 pubmed publisher
Palmieri E, Menga A, Martín Pérez R, Quinto A, Riera Domingo C, De Tullio G, et al. Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis. Cell Rep. 2017;20:1654-1666 pubmed publisher
Garcia Romero N, Carrión Navarro J, Esteban Rubio S, Lázaro Ibáñez E, Peris Celda M, Alonso M, et al. DNA sequences within glioma-derived extracellular vesicles can cross the intact blood-brain barrier and be detected in peripheral blood of patients. Oncotarget. 2017;8:1416-1428 pubmed publisher
Ola R, Dubrac A, Han J, Zhang F, Fang J, Larrivee B, et al. PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia. Nat Commun. 2016;7:13650 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1320
SKU :
AF1320
product name :
Mouse Endoglin/CD105 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse Endoglin/CD105 Antibody from R&D Systems is a goat polyclonal antibody to Endoglin/CD105. This antibody reacts with human,mouse,transgenic mouse,xenograft. The Mouse Endoglin/CD105 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Flow Cytometry,Simple Western,CyTOF-ready.
target :
Endoglin/CD105
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Simple Western 5 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, Immunohistochemistry 5-15 ug/mL, Immunocytochemistry 5-15 ug/mL, CyTOF-ready
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Endoglin/CD105, Glu27-Gly581, Accession # Q8K100
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse,Xenograft
specificity :
Detects mouse Endoglin in direct ELISAs and Western blots. In direct ELISAs, less than 20% cross-reactivity with recombinant rat Endoglin is observed and less than 5% cross-reactivity with recombinant human Endoglin is observed.
gene symbol :
ENG
top caption :
Detection of Mouse Endoglin/CD105 antibody by Western Blot.
accessionNumbers :
Q8K100
applications :
Flow Cytometry,Simple Western,CyTOF-ready,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
509 USD
alt names :
CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, ENG, HHT1FLJ41744, ORW, ORW1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.