product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Notch-3 Antibody
catalog :
AF1308
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 5
Reference
Meah A, Vedarethinam V, Bronstein R, Gujarati N, Jain T, Mallipattu S, et al. Single-Cell Spatial MIST for Versatile, Scalable Detection of Protein Markers. Biosensors (Basel). 2023;13: pubmed publisher
Wei K, Korsunsky I, Marshall J, Gao A, Watts G, Major T, et al. Notch signalling drives synovial fibroblast identity and arthritis pathology. Nature. 2020;582:259-264 pubmed publisher
Diéguez Hurtado R, Kato K, Giaimo B, Nieminen Kelhä M, Arf H, Ferrante F, et al. Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes. Nat Commun. 2019;10:2817 pubmed publisher
Kato K, Diéguez Hurtado R, Park D, Hong S, Kato Azuma S, Adams S, et al. Pulmonary pericytes regulate lung morphogenesis. Nat Commun. 2018;9:2448 pubmed publisher
Zhang Y, Dong S, Wang J, Wang M, Chen M, Huang H. Involvement of Notch2 in all‑trans retinoic acid‑induced inhibition of mouse embryonic palate mesenchymal cell proliferation. Mol Med Rep. 2017;16:2538-2546 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1308
SKU :
AF1308
product name :
Mouse Notch-3 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse Notch-3 Antibody from R&D Systems is a goat polyclonal antibody to Notch-3. This antibody reacts with mouse. The Mouse Notch-3 Antibody has been validated for the following applications: Immunohistochemistry,Immunofluorescence,Western Blot,Immunohistochemistry-Paraffin,Flow Cytometry,Blockade of Receptor-ligand Interaction,CyTOF-ready.
target :
Notch-3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 1-15 ug/mL, Blockade of Receptor-ligand Interaction, Immunofluorescence 1-15 ug/mL, CyTOF-ready
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Notch-3, Ala40-Glu468, Accession # Q61982
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse Notch-3 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human Notch-3 is observed and less than 5% cross-reactivity with recombinant rat (rr) Notch-1 and rrNotch-2 is observed.
gene symbol :
NOTCH3
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
accessionNumbers :
Q61982
applications :
Flow Cytometry,Blockade of Receptor-ligand Interaction,Immunofluorescence,CyTOF-ready,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin
USD :
499 USD
alt names :
CADASIL, CASILneurogenic locus notch homolog protein 3, Notch (Drosophila) homolog 3, notch 3Notch homolog 3 (Drosophila), Notch homolog 3, Notch3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.