product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ULBP-2/5/6 Antibody
catalog :
AF1298
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 1
  • western blot; human; loading ...; fig 5b
Sturgill E, Malouli D, Hansen S, Burwitz B, Seo S, Schneider C, et al. Natural Killer Cell Evasion Is Essential for Infection by Rhesus Cytomegalovirus. PLoS Pathog. 2016;12:e1005868 pubmed publisher
Fielding C, Sabberwal P, Williamson J, Greenwood E, Crozier T, Zelek W, et al. SARS-CoV-2 host-shutoff impacts innate NK cell functions, but antibody-dependent NK activity is strongly activated through non-spike antibodies. elife. 2022;11: pubmed publisher
Joung J, Kirchgatterer P, Singh A, Cho J, Nety S, Larson R, et al. CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nat Commun. 2022;13:1606 pubmed publisher
Jeon S, Kim H, Kwon J, Baek S, Ri H, Choi H, et al. Role of Sevoflurane on Natural Killer Group 2, Member D-Mediated Immune Response in Non-Small-Cell Lung Cancer: An In Vitro Study. Med Sci Monit. 2020;26:e926395 pubmed publisher
Okita R, Maeda A, Shimizu K, Nojima Y, Saisho S, Nakata M. Clinicopathological relevance of tumor expression of NK group 2 member D ligands in resected non-small cell lung cancer. Oncotarget. 2019;10:6805-6815 pubmed publisher
Leung W, Vong Q, Lin W, Bouck D, Wendt S, Sullivan E, et al. PRL-3 mediates the protein maturation of ULBP2 by regulating the tyrosine phosphorylation of HSP60. J Immunol. 2015;194:2930-41 pubmed publisher
product information
master code :
AF1298
SKU :
AF1298
product name :
Human ULBP-2/5/6 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human ULBP-2/5/6 Antibody from R&D Systems is a goat polyclonal antibody to ULBP-2/5/6. This antibody reacts with human. The Human ULBP-2/5/6 Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Blockade of Receptor-ligand Interaction.
target :
ULBP-2/5/6
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human ULBP-2, Gly26-Ser217, Accession # Q9BZM5
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human ULBP-2, ULBP-5, and RAET1L/ULBP-6 in Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human (rh) ULBP-1, rhULBP-3, and rhULBP-4 is observed.
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
ULBP-2/5/6 antibody in Human Colon Cancer Tissue by Immunohistochemistry (IHC-P).
accessionNumbers :
Q9BZM5
applications :
Flow Cytometry,Immunoprecipitation,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Blockade of Receptor-ligand Interaction
USD :
519 USD
alt names :
ALCAN-alpha, N2DL2, NKG2DL2, RAET1G, RAET1H, RAET1L, UL16 binding protein 2, ULBP2, ULBP5, ULBP6
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.