Human Serpin C1/Antithrombin-III Antibody | R&D Systems AF1267 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Serpin C1/Antithrombin-III Antibody

catalog :

AF1267

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, neutralization, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Kraaijvanger R, Janssen Bon xe1 s M, Grutters J, Paspali I, Veltkamp M, de Kleijn D, et al. Decreased serpin C1 in extracellular vesicles predicts response to methotrexate treatment in patients with pulmonary sarcoidosis. Respir Res. 2024;25:166 pubmed publisher
Basu A, Champagne R, Patel N, Nicholson E, Weiss R. TFCP2 is a transcriptional regulator of heparan sulfate assembly and melanoma cell growth. J Biol Chem. 2023;299:104713 pubmed publisher
Xu D, Wu J, Chen J, Jiang L, Chen J, Bao W, et al. Cullin 2-RBX1 E3 ligase and USP2 regulate antithrombin ubiquitination and stability. FASEB J. 2021;35:e21800 pubmed publisher
Weiss R, Spahn P, Chiang A, Liu Q, Li J, Hamill K, et al. Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate. Nat Chem Biol. 2021;17:684-692 pubmed publisher
Gerasimov A, Golderman V, Gofrit S, Aharoni S, Zohar D, Itsekson Hayosh Z, et al. Markers for neural degeneration and regeneration: novel highly sensitive methods for the measurement of thrombin and activated protein C in human cerebrospinal fluid. Neural Regen Res. 2021;16:2086-2092 pubmed publisher

product information

master code :

AF1267

SKU :

AF1267

product name :

Human Serpin C1/Antithrombin-III Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Serpin C1/Antithrombin-III Antibody from R&D Systems is a goat polyclonal antibody to Serpin C1/Antithrombin-III. This antibody reacts with human. The Human Serpin C1/Antithrombin-III Antibody has been validated for the following applications: Western Blot,ELISA Capture,Flow Cytometry,Immunoprecipitation,Neutralization.

target :

Serpin C1/Antithrombin-III

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Serpin C1/Antithrombin-III, His33-Lys464, Accession # P01008

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human Serpin C1/Antithrombin-III in direct ELISAs and Western blots. In direct ELISAs, approximately 45% cross-reactivity with recombinant mouse (rm) Serpin C1 is observed and less than 2% cross-reactivity with recombinant human (rh) Serpin A1, rhSerpin A3, rhSerpin A4, rhSerpin A5, rhSerpin F2, rmSerpin D1 and rhPEDF is observed.

gene symbol :

SERPINC1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

accessionNumbers :

P01008

applications :

Western Blot,ELISA Capture,Flow Cytometry,Immunoprecipitation,Neutralization

USD :

479 USD

alt names :

Antithrombin-III, AT3antithrombin-III, ATIII, ATIIIantithrombin III, MGC22579, serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1, serine-cysteine proteinase inhibitor clade C member 1, Serpin C1, serpin peptidase inhibitor, clade C (antithrombin), member 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage