product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Galectin-1 Antibody
catalog :
AF1245
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 9
Reference
Femel J, van Hooren L, Herre M, Cedervall J, Saupe F, Huijbers E, et al. Vaccination against galectin-1 promotes cytotoxic T-cell infiltration in melanoma and reduces tumor burden. Cancer Immunol Immunother. 2022;71:2029-2040 pubmed publisher
Morosi L, Cutine A, Cagnoni A, Manselle Cocco M, Croci D, Merlo J, et al. Control of intestinal inflammation by glycosylation-dependent lectin-driven immunoregulatory circuits. Sci Adv. 2021;7: pubmed publisher
Baloche V, Rivière J, Tran T, Gelin A, Bawa O, Signolle N, et al. Serial transplantation unmasks galectin-9 contribution to tumor immune escape in the MB49 murine model. Sci Rep. 2021;11:5227 pubmed publisher
Chiang M, Chen I, Hsu F, Chen Y, Tsai M, Hsu Y, et al. Gal-1 (Galectin-1) Upregulation Contributes to Abdominal Aortic Aneurysm Progression by Enhancing Vascular Inflammation. Arterioscler Thromb Vasc Biol. 2021;41:331-345 pubmed publisher
Ge J, Zheng Y, Tsuchida T, Furuya K, Isoda H, Taniguchi H, et al. Hepatic stellate cells contribute to liver regeneration through galectins in hepatic stem cell niche. Stem Cell Res Ther. 2020;11:425 pubmed publisher
Law H, Wright R, Iqbal A, Norling L, Cooper D. A Pro-resolving Role for Galectin-1 in Acute Inflammation. Front Pharmacol. 2020;11:274 pubmed publisher
Nambiar D, Aguilera T, Cao H, Kwok S, Kong C, Bloomstein J, et al. Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance. J Clin Invest. 2019;129:5553-5567 pubmed publisher
Tsai M, Chiang M, Tsai D, Yang C, Hou H, Li Y, et al. Galectin-1 Restricts Vascular Smooth Muscle Cell Motility Via Modulating Adhesion Force and Focal Adhesion Dynamics. Sci Rep. 2018;8:11497 pubmed publisher
Yang N, Zhang W, He T, Xing Y. Silencing of galectin-1 inhibits retinal neovascularization and ameliorates retinal hypoxia in a murine model of oxygen-induced ischemic retinopathy. Exp Eye Res. 2017;159:1-15 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1245
SKU :
AF1245
product name :
Mouse Galectin-1 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse Galectin-1 Antibody from R&D Systems is a goat polyclonal antibody to Galectin-1. This antibody reacts with mouse,rat. The Mouse Galectin-1 Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Western Blot,Neutralization,ELISA Capture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western,ELISA Capture (Matched Antibody Pair),Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
Galectin-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Simple Western 5 ug/mL, Immunohistochemistry 5-15 ug/mL, Intracellular Staining by Flow Cytometry 2.5 ug/10^6 cells, CyTOF-ready, ELISA Capture (Matched Antibody Pair) 0.2-0.8 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant mouse Galectin-1, Ala2-Glu135, Accession # P16045
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Rat
specificity :
Detects mouse Galectin-1 in ELISAs and Western blots. In sandwich ELISAs, less than 5% cross-reactivity with recombinant human (rh) Galectin-1 and less than 0.5% cross-reactivity with recombinant mouse (rm) Galectin-3, rhGalectin-4, rmGalectin-7, and rhGalectin-8 is observed.
gene symbol :
LGALS1
top caption :
Galectin-1 antibody in Mouse Thymus by Immunohistochemistry (IHC-Fr).
accessionNumbers :
P16045
applications :
Simple Western,ELISA Capture (Matched Antibody Pair),Intracellular Staining by Flow Cytometry,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry,ELISA Capture
USD :
489 USD
alt names :
14 kDa laminin-binding protein, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, BHL, DKFZp686E23103, gal-1, GAL1, Galaptin, galectin 1, galectin-1, Galectin1, GBP, HBL, HLBP14, HPL, L-14, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, lectin, galactoside-binding, soluble, 1, LGALS1, Putative MAPK-activating protein PM12, S-Lac lectin 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.