Human BAFF/BLyS/TNFSF13B Antibody | R&D Systems AF124 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BAFF/BLyS/TNFSF13B Antibody

catalog :

AF124

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 7

Reference
Ansari A, Sachan S, Jit B, Sharma A, Coshic P, Sette A, et al. An efficient immunoassay for the B cell help function of SARS-CoV-2-specific memory CD4+ T cells. Cell Rep Methods. 2022;2:100224 pubmed publisher
Talbot H, Saada S, Barthout E, Gallet P, Gachard N, Abraham J, et al. BDNF belongs to the nurse-like cell secretome and supports survival of B chronic lymphocytic leukemia cells. Sci Rep. 2020;10:12572 pubmed publisher
Rothbauer M, H xf6 ll G, Eilenberger C, Kratz S, Farooq B, Schüller P, et al. Monitoring tissue-level remodelling during inflammatory arthritis using a three-dimensional synovium-on-a-chip with non-invasive light scattering biosensing. Lab Chip. 2020;20:1461-1471 pubmed publisher
Cao Y, Lu G, Chen X, Chen X, Guo N, Li W. BAFF is involved in the pathogenesis of IgA nephropathy by activating the TRAF6/NF‑κB signaling pathway in glomerular mesangial cells. Mol Med Rep. 2020;21:795-805 pubmed publisher
Imbrechts M, De Samblancx K, Fierens K, Brisse E, Vandenhaute J, Mitera T, et al. IFN-γ stimulates CpG-induced IL-10 production in B cells via p38 and JNK signalling pathways. Eur J Immunol. 2018;48:1506-1521 pubmed publisher
Berggren O, Hagberg N, Alexsson A, Weber G, Rönnblom L, Eloranta M. Plasmacytoid dendritic cells and RNA-containing immune complexes drive expansion of peripheral B cell subsets with an SLE-like phenotype. PLoS ONE. 2017;12:e0183946 pubmed publisher
Saulep Easton D, Vincent F, Quah P, Wei A, Ting S, Croce C, et al. The BAFF receptor TACI controls IL-10 production by regulatory B cells and CLL B cells. Leukemia. 2016;30:163-72 pubmed publisher

product information

brand :

R&D Systems

master code :

AF124

SKU :

AF124

product name :

Human BAFF/BLyS/TNFSF13B Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human BAFF/BLyS/TNFSF13B Antibody from R&D Systems is a goat polyclonal antibody to BAFF/BLyS/TNFSF13B. This antibody reacts with human,porcine. The Human BAFF/BLyS/TNFSF13B Antibody has been validated for the following applications: Neutralization,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry.

target :

BAFF/BLyS/TNFSF13B

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 3-12 ng/mL

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human BAFF/BLyS/TNFSF13B, Ala134-Leu285, Accession # Q9Y275

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Porcine

specificity :

Detects human BAFF/BLyS/TNFSF13B in direct ELISAs and Western blots. In direct ELISAs, less than 15% cross-reactivity with recombinant murine BAFF and less than 1% cross-reactivity with recombinant human (rh) APRIL is observed.

gene symbol :

TNFSF13B

endotoxin note :

<0.60 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced By BAFF/BLyS/TNFSF13B and Neutralization by Human BAFF/BLyS/TNFSF13B Antibody.

accessionNumbers :

Q9Y275

applications :

Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Neutralization,Immunocytochemistry

USD :

509 USD

alt names :

ApoL related ligand TALL-1, B lymphocyte stimulator, BAFFB-cell activating factor, B-cell-activating factor, BLyS, BLYSB-lymphocyte stimulator, CD257, CD257 antigen, Dendritic cell-derived TNF-like molecule, DTL, TALL1, TALL-1delta BAFF, TALL1Delta4 BAFF, THANK, TNF and ApoL-related leukocyte expressed ligand 1, TNF- and APOL-related leukocyte expressed ligand 1, TNF homolog that activates apoptosis, TNFSF13B, TNFSF20, tumor necrosis factor (ligand) superfamily, member 13b, tumor necrosis factor (ligand) superfamily, member 20, tumor necrosis factor ligand superfamily member 13B, tumor necrosis factor superfamily, member 13b, tumor necrosis factor-like protein ZTNF4, ZTNF4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage