Human PD-L2/B7-DC Antibody | R&D Systems AF1224 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human PD-L2/B7-DC Antibody

catalog :

AF1224

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 5

Reference
Jeong S, Lee N, Park M, Jeon K, Song W. Currently Used Laboratory Methodologies for Assays Detecting PD-1, PD-L1, PD-L2 and Soluble PD-L1 in Patients with Metastatic Breast Cancer. Cancers (Basel). 2021;13: pubmed publisher
Tago Y, Kobayashi C, Ogura M, Wada J, Yamaguchi S, Yamaguchi T, et al. Human amnion-derived mesenchymal stem cells attenuate xenogeneic graft-versus-host disease by preventing T cell activation and proliferation. Sci Rep. 2021;11:2406 pubmed publisher
Baruah P, Bullenkamp J, Wilson P, Lee M, Kaski J, Dumitriu I. TLR9 Mediated Tumor-Stroma Interactions in Human Papilloma Virus (HPV)-Positive Head and Neck Squamous Cell Carcinoma Up-Regulate PD-L1 and PD-L2. Front Immunol. 2019;10:1644 pubmed publisher
Obeid J, Erdag G, Smolkin M, Deacon D, Patterson J, Chen L, et al. PD-L1, PD-L2 and PD-1 expression in metastatic melanoma: Correlation with tumor-infiltrating immune cells and clinical outcome. Oncoimmunology. 2016;5:e1235107 pubmed publisher
Davies L, Heldring N, Kadri N, Le Blanc K. Mesenchymal Stromal Cell Secretion of Programmed Death-1 Ligands Regulates T Cell Mediated Immunosuppression. Stem Cells. 2017;35:766-776 pubmed publisher

product information

master code :

AF1224

SKU :

AF1224

product name :

Human PD-L2/B7-DC Antibody

unit size :

100 ug (also 25 ug)

description :

The Human PD-L2/B7-DC Antibody from R&D Systems is a goat polyclonal antibody to PD-L2/B7-DC/PDCD1LG2. This antibody reacts with human. The Human PD-L2/B7-DC Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Western Blot,Blockade of Receptor-ligand Interaction.

target :

PD-L2/B7-DC

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human PD-L2/B7-DC, Leu20-Pro219, Accession # Q9BQ51

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human PD-L2/B7-DC in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse PD-L2 is observed and less than 1% cross-reactivity with recombinant human (rh) B7-1, rhB7-2, rhB7-H1, rhB7-H2, rhB7-H3, rhB7-H3b and recombinant rat B7-1 is observed.

gene symbol :

PDCD1LG2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Human PD-L2/B7-DC antibody by Western Blot.

accessionNumbers :

Q9BQ51

applications :

Flow Cytometry,Immunoprecipitation,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Western Blot,Blockade of Receptor-ligand Interaction

USD :

509 USD

alt names :

B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, Butyrophilin-like Protein, CD273, CD273 antigen, CD273PD-1 ligand 2, MGC142240, PD-1-ligand 2, PDCD1L2MGC142238, PDCD1LG2, PDL2, PDL2B7DC, PD-L2PDCD1 ligand 2, programmed cell death 1 ligand 2, Programmed death ligand 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage