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company name :
R&D Systems
product type :
antibody
product name :
Human Aggrecan G1-IGD-G2 Domains Antibody
catalog :
AF1220
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section
more info or order :
citations: 15
Reference
Gómez Sequeda N, Mendivil Perez M, Jimenez Del Rio M, Lopera F, Velez Pardo C. Cholinergic-like neurons and cerebral spheroids bearing the PSEN1 p.Ile416Thr variant mirror Alzheimer's disease neuropathology. Sci Rep. 2023;13:12833 pubmed publisher
Chen M, Hu C, Hsu Y, Chiu Y, Chen K, Ueng S, et al. Characterization and Advancement of an Evaluation Method for the Treatment of Spontaneous Osteoarthritis in STR/ort Mice: GRGDS Peptides as a Potential Treatment for Osteoarthritis. Biomedicines. 2023;11: pubmed publisher
Wu J, Yeager K, Tavakol D, Morsink M, Wang B, Soni R, et al. Directed differentiation of human iPSCs into mesenchymal lineages by optogenetic control of TGF-β signaling. Cell Rep. 2023;42:112509 pubmed publisher
Yamazaki S, Hirayama R, Ikeda Y, Iseki S, Yoda T, Ikeda M. Hyaluronic acid hydrogels support to generate integrated bone formation through endochondral ossification in vivo using mesenchymal stem cells. PLoS ONE. 2023;18:e0281345 pubmed publisher
Jiang W, Glaeser J, Salehi K, Kaneda G, Mathkar P, Wagner A, et al. Single-cell atlas unveils cellular heterogeneity and novel markers in human neonatal and adult intervertebral discs. iScience. 2022;25:104504 pubmed publisher
Kondo M, Kameishi S, Kim K, Metzler N, Maak T, Hutchinson D, et al. Safety and efficacy of human juvenile chondrocyte-derived cell sheets for osteochondral defect treatment. NPJ Regen Med. 2021;6:65 pubmed publisher
Mikłosz A, Łukaszuk B, Supruniuk E, Grubczak K, Moniuszko M, Choromańska B, et al. Does TBC1D4 (AS160) or TBC1D1 Deficiency Affect the Expression of Fatty Acid Handling Proteins in the Adipocytes Differentiated from Human Adipose-Derived Mesenchymal Stem Cells (ADMSCs) Obtained from Subcutaneous and Visceral Fat Depots?. Cells. 2021;10: pubmed publisher
Liang C, Liu Z, Song M, Li W, Wu Z, Wang Z, et al. Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration. Cell Res. 2021;31:187-205 pubmed publisher
Asega A, Menezes M, Trevisan Silva D, Cajado Carvalho D, Bertholim L, Oliveira A, et al. Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases. Sci Rep. 2020;10:12912 pubmed publisher
Lopez Perez R, Brauer J, Rühle A, Trinh T, Sisombath S, Wuchter P, et al. Human mesenchymal stem cells are resistant to UV-B irradiation. Sci Rep. 2019;9:20000 pubmed publisher
Vander Beken S, de Vries J, Meier Schiesser B, Meyer P, Jiang D, Sindrilaru A, et al. Newly Defined ATP-Binding Cassette Subfamily B Member 5 Positive Dermal Mesenchymal Stem Cells Promote Healing of Chronic Iron-Overload Wounds via Secretion of Interleukin-1 Receptor Antagonist. Stem Cells. 2019;37:1057-1074 pubmed publisher
Yin W, Kim H, Wang S, Gunawan F, Li R, Buettner C, et al. Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis. Eur Respir J. 2019;53: pubmed publisher
Srisuthtayanont W, Pruksakorn D, Kongtawelert P, Pothacharoen P. Effects of sesamin on chondroitin sulfate proteoglycan synthesis induced by interleukin-1beta in human chondrocytes. BMC Complement Altern Med. 2017;17:286 pubmed publisher
Tatebayashi K, Tanaka Y, Nakano Doi A, Sakuma R, Kamachi S, Shirakawa M, et al. Identification of Multipotent Stem Cells in Human Brain Tissue Following Stroke. Stem Cells Dev. 2017;26:787-797 pubmed publisher
Rolandsson Enes S, Andersson Sjöland A, Skog I, Hansson L, Larsson H, Le Blanc K, et al. MSC from fetal and adult lungs possess lung-specific properties compared to bone marrow-derived MSC. Sci Rep. 2016;6:29160 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1220
SKU :
AF1220
product name :
Human Aggrecan G1-IGD-G2 Domains Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Aggrecan G1-IGD-G2 Domains Antibody from R&D Systems is a goat polyclonal antibody to Aggrecan. This antibody reacts with human,mouse,rat. The Human Aggrecan G1-IGD-G2 Domains Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
Aggrecan
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Immunocytochemistry 5-15 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Aggrecan, Val20-Arg675, Accession # NP_037359
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human Aggrecan in direct ELISAs and Western blots.
gene symbol :
ACAN
top caption :
Aggrecan antibody in Rat Mesenchymal Stem Cells by Immunocytochemistry (ICC).
accessionNumbers :
NP_037359
applications :
Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
519 USD
alt names :
ACAN, AGC1, AGC1SEDK, aggrecan, aggrecan core protein, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan 1, Chondroitin sulfate proteoglycan core protein 1, CSPCP, CSPG1, CSPG1aggrecan 1, CSPGCP, large aggregating proteoglycan, MSK16, MSK16AGCAN, SEDK
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.