Human/Mouse/Rat Phospho-JNK (T183/Y185) Antibody | R&D Systems AF1205 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat Phospho-JNK (T183/Y185) Antibody

catalog :

AF1205

quantity :

50 ug (also 25 ug)

price :

399 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry

more info or order :

R&D Systems product webpage

citations: 12

Reference
Liou G, Fleming Martinez A, D xf6 ppler H, Bastea L, Storz P. Inflammatory and alternatively activated macrophages independently induce metaplasia but cooperatively drive pancreatic precancerous lesion growth. iScience. 2023;26:106820 pubmed publisher
Suyama K, Sakai D, Hayashi S, Qu N, Terayama H, Kiyoshima D, et al. Bag-1 Protects Nucleus Pulposus Cells from Oxidative Stress by Interacting with HSP70. Biomedicines. 2023;11: pubmed publisher
Niu T, Wei Z, Fu J, Chen S, Wang R, Wang Y, et al. Venlafaxine, an anti-depressant drug, induces apoptosis in MV3 human melanoma cells through JNK1/2-Nur77 signaling pathway. Front Pharmacol. 2022;13:1080412 pubmed publisher
Ishijima T, Nakajima K. Changes of signaling molecules in the axotomized rat facial nucleus. J Chem Neuroanat. 2022;126:102179 pubmed publisher
Alors Pérez E, Bl xe1 zquez Encinas R, Alcal xe1 S, Viyuela Garc xed a C, Pedraza Arevalo S, Herrero Aguayo V, et al. Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug. J Exp Clin Cancer Res. 2021;40:382 pubmed publisher
Dey S, Udari L, Riverahernandez P, Kwon J, Willis B, Easler J, et al. Loss of miR-29a/b1 promotes inflammation and fibrosis in acute pancreatitis. JCI Insight. 2021;6: pubmed publisher
Mantawy E, Said R, Kassem D, Abdel Aziz A, Badr A. Novel molecular mechanisms underlying the ameliorative effect of N-acetyl-L-cysteine against ϒ-radiation-induced premature ovarian failure in rats. Ecotoxicol Environ Saf. 2020;206:111190 pubmed publisher
Falero Perez J, Sheibani N, Sorenson C. Bim expression modulates the pro-inflammatory phenotype of retinal astroglial cells. PLoS ONE. 2020;15:e0232779 pubmed publisher
Jiménez Vacas J, Herrero Aguayo V, Montero Hidalgo A, Gómez Gómez E, Fuentes Fayos A, León González A, et al. Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer. EBioMedicine. 2020;51:102547 pubmed publisher
Suyama K, Sakai D, Hirayama N, Nakamura Y, Matsushita E, Terayama H, et al. Effects of interleukin-17A in nucleus pulposus cells and its small-molecule inhibitors for intervertebral disc disease. J Cell Mol Med. 2018;22:5539-5551 pubmed publisher
Janczar S, Nautiyal J, Xiao Y, Curry E, Sun M, Zanini E, et al. WWOX sensitises ovarian cancer cells to paclitaxel via modulation of the ER stress response. Cell Death Dis. 2017;8:e2955 pubmed publisher
Mantawy E, Esmat A, El Bakly W, Salah ElDin R, El Demerdash E. Mechanistic clues to the protective effect of chrysin against doxorubicin-induced cardiomyopathy: Plausible roles of p53, MAPK and AKT pathways. Sci Rep. 2017;7:4795 pubmed publisher

product information

master code :

AF1205

SKU :

AF1205

product name :

Human/Mouse/Rat Phospho-JNK (T183/Y185) Antibody

unit size :

50 ug (also 25 ug)

description :

The Human/Mouse/Rat Phospho-JNK (T183/Y185) Antibody from R&D Systems is a rabbit polyclonal antibody to JNK1/2/3. This antibody reacts with human,mouse,rat,transgenic mouse. The Human/Mouse/Rat Phospho-JNK (T183/Y185) Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Simple Western.

target :

JNK

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rabbit

immunogen :

Phosphopeptide containing human, rat, and mouse JNK1 T183/Y185 site

isotype :

IgG

purity :

Antigen and protein A Affinity-purified

species :

Human,Mouse,Rat,Transgenic Mouse

specificity :

Detects human, mouse and rat p46 and p54 JNK when dually phosphorylated at sites homologous to T183/Y185 of JNK1 and JNK2, and T221/Y223 of JNK3 in Western blots.

gene symbol :

MAPK8IP3

top caption :

Detection of Human and Mouse Phospho-JNK (T183/Y185) antibody by Western Blot.

applications :

Immunohistochemistry,Western Blot,Simple Western

USD :

399 USD

alt names :

c-Jun N-terminal kinase 1, EC 2.7.11, EC 2.7.11.24, JNK1 alpha protein kinase, JNK1 beta protein kinase, JNK1JNK1A2, JNK-46, JUN N-terminal kinase, MAP kinase 8, MAPK 8, MAPK10, MAPK8, MAPK9, mitogen-activated protein kinase 8, mitogen-activated protein kinase 8 isoform JNK1 alpha1, mitogen-activated protein kinase 8 isoform JNK1 beta2, PRKM8, PRKM8JNK, protein kinase JNK1, SAPK1, SAPK1 alpha, SAPK1 beta, SAPK1JNK21B1/2, Stress-activated protein kinase 1, Stress-activated protein kinase JNK1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage