product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse TREM-1 Antibody
catalog :
AF1187
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 5
Reference
Wu K, Liu Y, Shao S, Song W, Chen X, Dong Y, et al. The microglial innate immune receptors TREM-1 and TREM-2 in the anterior cingulate cortex (ACC) drive visceral hypersensitivity and depressive-like behaviors following DSS-induced colitis. Brain Behav Immun. 2023;112:96-117 pubmed publisher
Seo D, Che X, Kim S, Kim D, Ma H, Kim J, et al. Triggering Receptor Expressed on Myeloid Cells-1 Agonist Regulates Intestinal Inflammation via Cd177+ Neutrophils. Front Immunol. 2021;12:650864 pubmed publisher
Vandestienne M, Zhang Y, Santos Zas I, Al Rifai R, Joffre J, Giraud A, et al. TREM-1 orchestrates angiotensin II-induced monocyte trafficking and promotes experimental abdominal aortic aneurysm. J Clin Invest. 2021;131: pubmed publisher
Schlepckow K, Monroe K, Kleinberger G, Cantuti Castelvetri L, Parhizkar S, Xia D, et al. Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region. EMBO Mol Med. 2020;12:e11227 pubmed publisher
Denning N, Aziz M, Murao A, Gurien S, Ochani M, Prince J, et al. Extracellular CIRP as an endogenous TREM-1 ligand to fuel inflammation in sepsis. JCI Insight. 2020;5: pubmed publisher
product information
master code :
AF1187
SKU :
AF1187
product name :
Mouse TREM-1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse TREM-1 Antibody from R&D Systems is a goat polyclonal antibody to TREM1. This antibody reacts with mouse. The Mouse TREM-1 Antibody has been validated for the following applications: Bioassay,Immunohistochemistry,Western Blot,Flow Cytometry,Agonist Activity,ELISA Capture (Matched Antibody Pair),Immunocytochemistry,CyTOF-ready.
target :
TREM-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse TREM-1, Ala21-Ser202, Accession # Q9JKE2
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse TREM-1 in ELISAs and Western blots. In sandwich immunoassays, less than 0.2% cross-reactivity with recombinant human (rh) TREM-1 is observed.
gene symbol :
TREM1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
TREM-1 antibody in Mouse Splenocytes by Immunocytochemistry (ICC).
accessionNumbers :
Q9JKE2
applications :
Bioassay,Immunohistochemistry,Western Blot,Flow Cytometry,Agonist Activity,ELISA Capture (Matched Antibody Pair),Immunocytochemistry,CyTOF-ready
USD :
489 USD
alt names :
CD354, CD354 antigen, TREM1, TREM-1Triggering receptor expressed on monocytes 1, triggering receptor expressed on myeloid cells 1, triggering-receptor TREM1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.