Human Cathepsin S Antibody | R&D Systems AF1183 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Cathepsin S Antibody

catalog :

AF1183

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, chicken

application :

western blot, ELISA, immunohistochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:2000; loading ...; fig 7i	Wang S, Luke C, Pak S, Shi V, Chen L, Moore J, et al. SERPINB3 (SCCA1) inhibits cathepsin L and lysoptosis, protecting cervical cancer cells from chemoradiation. Commun Biol. 2022;5:46 pubmed publisher
western blot; human; 1:500; loading ...; fig 1a	Tu N, Inoue K, Chen E, Anderson B, Sawicki C, Scheff N, et al. Cathepsin S Evokes PAR2-Dependent Pain in Oral Squamous Cell Carcinoma Patients and Preclinical Mouse Models. Cancers (Basel). 2021;13: pubmed publisher
	Bararia D, Hildebrand J, Stolz S, Haebe S, Alig S, Trevisani C, et al. Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma. Cell Rep. 2020;31:107522 pubmed publisher
	Bailleul G, Kravtzoff A, Joulin Giet A, Lecaille F, Labas V, Meudal H, et al. The Unusual Resistance of Avian Defensin AvBD7 to Proteolytic Enzymes Preserves Its Antibacterial Activity. PLoS ONE. 2016;11:e0161573 pubmed publisher
	Huang C, Lee C, Lin H, Chang J. Cathepsin S attenuates endosomal EGFR signalling: A mechanical rationale for the combination of cathepsin S and EGFR tyrosine kinase inhibitors. Sci Rep. 2016;6:29256 pubmed publisher
	Liu W, Liu D, Cheng K, Liu Y, Xing S, Chi P, et al. Evaluating the diagnostic and prognostic value of circulating cathepsin S in gastric cancer. Oncotarget. 2016;7:28124-38 pubmed publisher
	Hamon Y, Legowska M, HervÃ© V, Dallet Choisy S, Marchand Adam S, Vanderlynden L, et al. Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases. J Biol Chem. 2016;291:8486-99 pubmed publisher

product information

master code :

AF1183

SKU :

AF1183

product name :

Human Cathepsin S Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Cathepsin S Antibody from R&D Systems is a goat polyclonal antibody to Cathepsin S. This antibody reacts with avian - chicken,human,mouse. The Human Cathepsin S Antibody has been validated for the following applications: Luminex Development,Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoprecipitation,Neutralization,ELISA Capture (Matched Antibody Pair).

target :

Cathepsin S

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Cathepsin S, Gln17-Ile331, Accession # P25774

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Avian - Chicken,Human,Mouse

specificity :

Detects human Cathepsin S in ELISAs and Western blots. In sandwich ELISAs, less than 0.05% cross-reactivity with recombinant human Cathepsin A, B, C, D, E, L, V, and X/Z/P is observed.

gene symbol :

CTSS

Antibody validation :

Knockout/Knockdown

top caption :

Cathepsin S antibody in Human Lymph Node by Immunohistochemistry (IHC-P).

accessionNumbers :

P25774

applications :

Luminex Development,Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoprecipitation,Neutralization,ELISA Capture (Matched Antibody Pair)

USD :

499 USD

alt names :

cathepsin S, CTSS, EC 3.4.22, EC 3.4.22.27, FLJ50259, MGC3886

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage