Human DPPIV/CD26 Antibody | R&D Systems AF1180 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human DPPIV/CD26 Antibody

catalog :

AF1180

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, other, immunohistochemistry knockout validation

more info or order :

R&D Systems product webpage

citations: 32

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry knockout validation; human; 1:200; loading ...; fig 3d	Beumer J, Geurts M, Lamers M, Puschhof J, Zhang J, van der Vaart J, et al. A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses. Nat Commun. 2021;12:5498 pubmed publisher
other; human; 1:10; loading ...; fig s4f, s4h	Hess M, Krainer I, Filipek P, Witting B, Gutleben K, Vietor I, et al. Advanced Microscopy for Liver and Gut Ultrastructural Pathology in Patients with MVID and PFIC Caused by MYO5B Mutations. J Clin Med. 2021;10: pubmed publisher
	Mayer C, Nehring S, K xfc cken M, Repnik U, Seifert S, Sljukic A, et al. Apical bulkheads accumulate as adaptive response to impaired bile flow in liver disease. EMBO Rep. 2023;24:e57181 pubmed publisher
	Chen J, Yang X, Si H, Gong Q, Que T, Li J, et al. A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry. Cell. 2023;186:850-863.e16 pubmed publisher
	Klee K, Hess M, Lohm xfc ller M, Herzog S, Pfaller K, M xfc ller T, et al. A CRISPR screen in intestinal epithelial cells identifies novel factors for polarity and apical transport. elife. 2023;12: pubmed publisher
	Beumer J, Bauz xe1 Martinez J, Veth T, Geurts V, Boot C, Gilliam Vigh H, et al. Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models. Proc Natl Acad Sci U S A. 2022;119:e2212057119 pubmed publisher
	Kadefors M, Berlin F, Wildt M, Dellgren G, Rolandsson Enes S, Aspberg A, et al. Dipeptidyl peptidase 4 expression is not associated with an activated fibroblast phenotype in idiopathic pulmonary fibrosis. Front Pharmacol. 2022;13:953771 pubmed publisher
	Patten J, Keiser P, Morselli Gysi D, Menichetti G, Mori H, Donahue C, et al. Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization. iScience. 2022;25:104925 pubmed publisher
	Turunen T, Magris M, Malinen M, Kek xe4 l xe4 inen J. Seminal-Plasma-Mediated Effects on Sperm Performance in Humans. Cells. 2022;11: pubmed publisher
	Li K, Wohlford Lenane C, Bartlett J, McCray P. Inter-individual Variation in Receptor Expression Influences MERS-CoV Infection and Immune Responses in Airway Epithelia. Front Public Health. 2021;9:756049 pubmed publisher
	Nadolny C, Zhang X, Chen Q, Hashmi S, Ali W, Hemme C, et al. Dysregulation and activities of ubiquitin specific peptidase 2b in the pathogenesis of hepatocellular carcinoma. Am J Cancer Res. 2021;11:4746-4767 pubmed
	Ogawa Y, Akimoto Y, Ikemoto M, Goto Y, Ishikawa A, Ohta S, et al. Stability of human salivary extracellular vesicles containing dipeptidyl peptidase IV under simulated gastrointestinal tract conditions. Biochem Biophys Rep. 2021;27:101034 pubmed publisher
	Kamada S, Namekawa T, Ikeda K, Suzuki T, Kagawa M, Takeshita H, et al. Functional inhibition of cancer stemness-related protein DPP4 rescues tyrosine kinase inhibitor resistance in renal cell carcinoma. Oncogene. 2021;40:3899-3913 pubmed publisher
	Coate K, Cha J, Shrestha S, Wang W, Gonçalves L, Almaca J, et al. SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in β Cells. Cell Metab. 2020;32:1028-1040.e4 pubmed publisher
	Takagi S, Hirokawa M, Nagashima K, Higuchi M, Kadota K, Ishikawa R, et al. Diagnostic significance of apical membranous and cytoplasmic dot-like CD26 expression in encapsulated follicular variant of papillary thyroid carcinoma: a useful marker for capsular invasion. Endocr J. 2020;67:1207-1214 pubmed publisher
	Kolanowski T, Rozwadowska N, Zimna A, Nowaczyk M, Siatkowski M, Łabędź W, et al. Chromatin and transcriptome changes in human myoblasts show spatio-temporal correlations and demonstrate DPP4 inhibition in differentiated myotubes. Sci Rep. 2020;10:14336 pubmed publisher
	Worthen C, Cui Y, Orringer J, Johnson T, Voorhees J, Fisher G. CD26 Identifies a Subpopulation of Fibroblasts that Produce the Majority of Collagen during Wound Healing in Human Skin. J Invest Dermatol. 2020;140:2515-2524.e3 pubmed publisher
	Peng W, Rao D, Zhang M, Shi Y, Wu J, Nie G, et al. Teneligliptin prevents doxorubicin-induced inflammation and apoptosis in H9c2 cells. Arch Biochem Biophys. 2020;683:108238 pubmed publisher
	Menachery V, Dinnon K, Yount B, McAnarney E, Gralinski L, Hale A, et al. Trypsin Treatment Unlocks Barrier for Zoonotic Bat Coronavirus Infection. J Virol. 2020;94: pubmed publisher
	Chen Y, Hsu H, Wang S, Lien H, Lu H, Peng S. Entry of Scotophilus Bat Coronavirus-512 and Severe Acute Respiratory Syndrome Coronavirus in Human and Multiple Animal Cells. Pathogens. 2019;8: pubmed publisher
	Schmid N, Flenkenthaler F, Stöckl J, Dietrich K, Köhn F, Schwarzer J, et al. Insights into replicative senescence of human testicular peritubular cells. Sci Rep. 2019;9:15052 pubmed publisher
	Hayashi M, Madokoro H, Yamada K, Nishida H, Morimoto C, Sakamoto M, et al. Novel Antibody-Drug Conjugate with Anti-CD26 Humanized Monoclonal Antibody and Transcription Factor IIH (TFIIH) Inhibitor, Triptolide, Inhibits Tumor Growth via Impairing mRNA Synthesis. Cancers (Basel). 2019;11: pubmed publisher
	Vazquez Iglesias L, Barcia Castro L, Rodríguez Quiroga M, Páez de la Cadena M, Rodríguez Berrocal J, Cordero O. Surface expression marker profile in colon cancer cell lines and sphere-derived cells suggests complexity in CD26+ cancer stem cells subsets. Biol Open. 2019;8: pubmed publisher
	Hatano R, Yamada T, Madokoro H, Otsuka H, Komiya E, Itoh T, et al. Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens. PLoS ONE. 2019;14:e0218330 pubmed publisher
	Iwata Yoshikawa N, Okamura T, Shimizu Y, Kotani O, Sato H, Sekimukai H, et al. Acute Respiratory Infection in Human Dipeptidyl Peptidase 4-Transgenic Mice Infected with Middle East Respiratory Syndrome Coronavirus. J Virol. 2019;93: pubmed publisher
	Cockrell A, Johnson J, Moore I, Liu D, Bock K, Douglas M, et al. A spike-modified Middle East respiratory syndrome coronavirus (MERS-CoV) infectious clone elicits mild respiratory disease in infected rhesus macaques. Sci Rep. 2018;8:10727 pubmed publisher
	Haverkamp A, Lehmbecker A, Spitzbarth I, Widagdo W, Haagmans B, Segales J, et al. Experimental infection of dromedaries with Middle East respiratory syndrome-Coronavirus is accompanied by massive ciliary loss and depletion of the cell surface receptor dipeptidyl peptidase 4. Sci Rep. 2018;8:9778 pubmed publisher
	Chu H, Chan C, Zhang X, Wang Y, Yuan S, Zhou J, et al. Middle East respiratory syndrome coronavirus and bat coronavirus HKU9 both can utilize GRP78 for attachment onto host cells. J Biol Chem. 2018;293:11709-11726 pubmed publisher
	Luo C, Wang N, Yang X, Liu H, Zhang W, Li B, et al. Discovery of Novel Bat Coronaviruses in South China That Use the Same Receptor as Middle East Respiratory Syndrome Coronavirus. J Virol. 2018;92: pubmed publisher
	Li W, Hulswit R, Widjaja I, Raj V, McBride R, Peng W, et al. Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein. Proc Natl Acad Sci U S A. 2017;114:E8508-E8517 pubmed publisher
	Mah W, Jiang G, Olver D, Gallant Behm C, Wiebe C, Hart D, et al. Elevated CD26 Expression by Skin Fibroblasts Distinguishes a Profibrotic Phenotype Involved in Scar Formation Compared to Gingival Fibroblasts. Am J Pathol. 2017;187:1717-1735 pubmed publisher
	Angevin E, Isambert N, Trillet Lenoir V, You B, Alexandre J, Zalcman G, et al. First-in-human phase 1 of YS110, a monoclonal antibody directed against CD26 in advanced CD26-expressing cancers. Br J Cancer. 2017;116:1126-1134 pubmed publisher

product information

brand :

R&D Systems

master code :

AF1180

SKU :

AF1180

product name :

Human DPPIV/CD26 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human DPPIV/CD26 Antibody from R&D Systems is a goat polyclonal antibody to DPPIV/CD26. This antibody reacts with bat,camelid,ferret,human,mouse,primate,rat. The Human DPPIV/CD26 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Western Blot,Blocking,Immunoprecipitation,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Simple Western.

target :

DPPIV/CD26

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.2 ug/mL, Simple Western 2 ug/mL, Immunohistochemistry 1-15 ug/mL, Immunocytochemistry 1-15 ug/mL

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human DPPIV/CD26 (Catalog # 1180-SE ), Asp34-Pro766, Accession # Q53TN1

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Bat,Camelid,Ferret,Human,Mouse,Primate,Rat

specificity :

Detects human DPPIV/CD26 in direct ELISAs and Western blots.

gene symbol :

DPP4

top caption :

Detection of Human DPPIV/CD26 antibody by Western Blot.

accessionNumbers :

Q53TN1

applications :

Simple Western,Blocking,Flow Cytometry,Immunohistochemistry,Immunoprecipitation,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry

USD :

489 USD

alt names :

ADABP, ADCP-2, ADCP2DPP IV, Adenosine deaminase complexing protein 2TP103, CD26, CD26 antigen, CD26T-cell activation antigen CD26, dipeptidyl peptidase 4, Dipeptidyl peptidase IV, dipeptidylpeptidase 4, dipeptidyl-peptidase 4, dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2), DPP4, DPPIV, EC 3.4.14.5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage