product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse NGFR/TNFRSF16 Antibody
catalog :
AF1157
quantity :
100 ug (also 25 ug)
price :
499 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 18
Reference
Dasgupta S, Montroull L, Pandya M, Zanin J, Wang W, Wu Z, et al. Cortical Brain Injury Causes Retrograde Degeneration of Afferent Basal Forebrain Cholinergic Neurons via the p75NTR. Eneuro. 2023;10: pubmed publisher
Sharma S, Littman R, Tompkins J, Arneson D, Contreras J, Dajani A, et al. Tiered sympathetic control of cardiac function revealed by viral tracing and single cell transcriptome profiling. elife. 2023;12: pubmed publisher
Schmidbauer D, Fink S, Rousset F, L xf6 wenheim H, Senn P, Glueckert R. Closing the Gap between the Auditory Nerve and Cochlear Implant Electrodes: Which Neurotrophin Cocktail Performs Best for Axonal Outgrowth and Is Electrical Stimulation Beneficial?. Int J Mol Sci. 2023;24: pubmed publisher
Sharma S, Littman R, Tompkins J, Arneson D, Contreras J, Dajani A, et al. Tiered Sympathetic Control of Cardiac Function Revealed by Viral Tracing and Single Cell Transcriptome Profiling. bioRxiv. 2023;: pubmed publisher
Subirada P, Tovo A, Vaglienti M, Luna Pinto J, Saragovi H, S xe1 nchez M, et al. Etiological Roles of p75NTR in a Mouse Model of Wet Age-Related Macular Degeneration. Cells. 2023;12: pubmed publisher
Fan M, Shi H, Yao H, Wang W, Zhang Y, Jiang C, et al. BMSCs Promote Differentiation of Enteric Neural Precursor Cells to Maintain Neuronal Homeostasis in Mice With Enteric Nerve Injury. Cell Mol Gastroenterol Hepatol. 2023;15:511-531 pubmed publisher
Ariyasu Y, Sato Y, Isobe Y, Taniguchi K, Yanagita M, Arita M. Sterol O-Acyltransferase Inhibition Ameliorates High-Fat Diet-Induced Renal Fibrosis and Tertiary Lymphoid Tissue Maturation after Ischemic Reperfusion Injury. Int J Mol Sci. 2022;23: pubmed publisher
Morano N, Smith R, Danelon V, Schreiner R, Patel U, Herrera N, et al. Human immunomodulatory ligand B7-1 mediates synaptic remodeling via the p75 neurotrophin receptor. J Clin Invest. 2022;132: pubmed publisher
Simmons D, Mills B, Butler Iii R, Kuan J, McHugh T, Akers C, et al. Neuroimaging, Urinary, and Plasma Biomarkers of Treatment Response in Huntington's Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31. Neurotherapeutics. 2021;18:1039-1063 pubmed publisher
Asuni G, Speidell A, Mocchetti I. Neuronal apoptosis induced by morphine withdrawal is mediated by the p75 neurotrophin receptor. J Neurochem. 2021;158:169-181 pubmed publisher
Montroull L, Rothbard D, Kanal H, D Mello V, Dodson V, Troy C, et al. Proneurotrophins Induce Apoptotic Neuronal Death After Controlled Cortical Impact Injury in Adult Mice. ASN Neuro. 2020;12:1759091420930865 pubmed publisher
Groves N, O Keeffe I, Lee W, Toft A, Blackmore D, Bandhavkar S, et al. Blockade of TrkB but not p75NTR activates a subpopulation of quiescent neural precursor cells and enhances neurogenesis in the adult mouse hippocampus. Dev Neurobiol. 2019;79:868-879 pubmed publisher
Meier S, Alfonsi F, Kurniawan N, Milne M, Kasherman M, Delogu A, et al. The p75 neurotrophin receptor is required for the survival of neuronal progenitors and normal formation of the basal forebrain, striatum, thalamus and neocortex. Development. 2019;146: pubmed publisher
Saadipour K, Tiberi A, Lombardo S, Grajales E, Montroull L, Mañucat Tan N, et al. Regulation of BACE1 expression after injury is linked to the p75 neurotrophin receptor. Mol Cell Neurosci. 2019;99:103395 pubmed publisher
Baho E, Chattopadhyaya B, Lavertu Jolin M, Mazziotti R, Awad P, Chehrazi P, et al. p75 Neurotrophin Receptor Activation Regulates the Timing of the Maturation of Cortical Parvalbumin Interneuron Connectivity and Promotes Juvenile-like Plasticity in Adult Visual Cortex. J Neurosci. 2019;39:4489-4510 pubmed publisher
Greenwood S, Montroull L, Volosin M, Scharfman H, Teng K, Light M, et al. A Novel Neuroprotective Mechanism for Lithium That Prevents Association of the p75NTR-Sortilin Receptor Complex and Attenuates proNGF-Induced Neuronal Death In Vitro and In Vivo. Eneuro. 2018;5: pubmed publisher
Jia R, Shepheard S, Jin J, Hu F, Zhao X, Xue L, et al. Urinary Extracellular Domain of Neurotrophin Receptor p75 as a Biomarker for Amyotrophic Lateral Sclerosis in a Chinese cohort. Sci Rep. 2017;7:5127 pubmed publisher
Szklany K, Ruiter E, Mian F, Kunze W, Bienenstock J, Forsythe P, et al. Superior Cervical Ganglia Neurons Induce Foxp3+ Regulatory T Cells via Calcitonin Gene-Related Peptide. PLoS ONE. 2016;11:e0152443 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1157
SKU :
AF1157
product name :
Mouse NGFR/TNFRSF16 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse NGFR/TNFRSF16 Antibody from R&D Systems is a goat polyclonal antibody to NGFR/TNFRSF16/p75NTR. This antibody reacts with human,mouse,porcine,rat. The Mouse NGFR/TNFRSF16 Antibody has been validated for the following applications: Immunocytochemistry,ELISA Development (Detection),Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Frozen.
target :
NGFR/TNFRSF16
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 2 ug/mL, Immunohistochemistry 5-15 ug/mL
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse NGF R/TNFRSF16, Gly20-Asn243, Accession # Q9Z0W1
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Porcine,Rat
specificity :
Detects mouse NGF R/TNFRSF16 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human NGF R/TNFRSF16 is observed.
gene symbol :
NGFR
top caption :
Detection of Mouse NGF R/TNFRSF16 antibody by Western Blot.
accessionNumbers :
Q9Z0W1
applications :
ELISA Development (Detection),Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry
USD :
499 USD
alt names :
CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF R, NGF receptor, p75 ICD, p75 NTR, TNFRSF16, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.