Human/Mouse/Rat RAGE/AGER Antibody | R&D Systems AF1145 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat RAGE/AGER Antibody

catalog :

AF1145

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 24

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:300; fig 5c	Dinnon K, Leist S, Okuda K, Dang H, Fritch E, Gully K, et al. SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice. Sci Transl Med. 2022;14:eabo5070 pubmed publisher
	Chang T, Lan K, Wu C, Sheu M, Yang R, Liu S. Nε-(1-Carboxymethyl)-L-lysine/RAGE Signaling Drives Metastasis and Cancer Stemness through ERK/NFκB axis in Osteosarcoma. Int J Biol Sci. 2024;20:880-896 pubmed publisher
	Schwertner K, Gelles K, Leitner J, Steinberger P, Gundacker C, Vrticka R, et al. Human intestine and placenta exhibit tissue-specific expression of RAGE isoforms. Heliyon. 2023;9:e18247 pubmed publisher
	Pujals M, Mayans C, Bellio C, M xe9 ndez O, Greco E, Fasani R, et al. RAGE/SNAIL1 signaling drives epithelial-mesenchymal plasticity in metastatic triple-negative breast cancer. Oncogene. 2023;42:2610-2628 pubmed publisher
	Kaiser A, Gatto A, Hanson K, Zhao R, Raj N, Ozawa M, et al. p53 governs an AT1 differentiation programme in lung cancer suppression. Nature. 2023;619:851-859 pubmed publisher
	Sucre J, Bock F, Negretti N, Benjamin J, Gulleman P, Dong X, et al. Alveolar repair following LPS-induced injury requires cell-ECM interactions. JCI Insight. 2023;8: pubmed publisher
	Konkimalla A, Konishi S, Kobayashi Y, Kadur Lakshminarasimha Murthy P, Macadlo L, Mukherjee A, et al. Multi-apical polarity of alveolar stem cells and their dynamics during lung development and regeneration. iScience. 2022;25:105114 pubmed publisher
	Konishi S, Tata A, Tata P. Defined conditions for long-term expansion of murine and human alveolar epithelial stem cells in three-dimensional cultures. STAR Protoc. 2022;3:101447 pubmed publisher
	Kadur Lakshminarasimha Murthy P, Sontake V, Tata A, Kobayashi Y, Macadlo L, Okuda K, et al. Human distal lung maps and lineage hierarchies reveal a bipotent progenitor. Nature. 2022;604:111-119 pubmed publisher
	Havas F, Krispin S, Cohen M, Loing E, Farge M, Suere T, et al. A Dunaliella salina Extract Counteracts Skin Aging under Intense Solar Irradiation Thanks to Its Antiglycation and Anti-Inflammatory Properties. Mar Drugs. 2022;20: pubmed publisher
	Sun X, Perl A, Li R, Bell S, Sajti E, Kalinichenko V, et al. A census of the lung: CellCards from LungMAP. Dev Cell. 2022;57:112-145.e2 pubmed publisher
	D Erminio D, Krishnamoorthy D, Lai A, Hoy R, Natelson D, Poeran J, et al. High fat diet causes inferior vertebral structure and function without disc degeneration in RAGE-KO mice. J Orthop Res. 2022;40:1672-1686 pubmed publisher
	Biswas I, Panicker S, Cai X, Giri H, Rezaie A. Extracellular Histones Bind Vascular Glycosaminoglycans and Inhibit the Anti-Inflammatory Function of Antithrombin. Cell Physiol Biochem. 2021;55:605-617 pubmed publisher
	Gokey J, Snowball J, Sridharan A, Sudha P, Kitzmiller J, Xu Y, et al. YAP regulates alveolar epithelial cell differentiation and AGER via NFIB/KLF5/NKX2-1. iScience. 2021;24:102967 pubmed publisher
	Scavello F, Zeni F, Milano G, Macrì F, Castiglione S, Zuccolo E, et al. Soluble Receptor for Advanced Glycation End-products regulates age-associated Cardiac Fibrosis. Int J Biol Sci. 2021;17:2399-2416 pubmed publisher
	Swami P, O Connell K, Thiyagarajan S, Crawford A, Patil P, Radhakrishnan P, et al. Inhibition of the Receptor for Advanced Glycation End Products Enhances the Cytotoxic Effect of Gemcitabine in Murine Pancreatic Tumors. Biomolecules. 2021;11: pubmed publisher
	Zhou G, Chen Z, Li J, Guo X, Qin K, Luo J, et al. Role of the Receptor for Advanced Glycation End Products in Heat Stress-Induced Endothelial Hyperpermeability in Acute Lung Injury. Front Physiol. 2020;11:1087 pubmed publisher
	Youk J, Kim T, Evans K, Jeong Y, Hur Y, Hong S, et al. Three-Dimensional Human Alveolar Stem Cell Culture Models Reveal Infection Response to SARS-CoV-2. Cell Stem Cell. 2020;27:905-919.e10 pubmed publisher
	Katsura H, Sontake V, Tata A, Kobayashi Y, Edwards C, Heaton B, et al. Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction. Cell Stem Cell. 2020;27:890-904.e8 pubmed publisher
	Scavello F, Zeni F, Tedesco C, Mensà E, Veglia F, Procopio A, et al. Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging. Aging (Albany NY). 2019;11:1648-1663 pubmed publisher
	Tang X, Snowball J, Xu Y, Na C, Weaver T, Clair G, et al. EMC3 coordinates surfactant protein and lipid homeostasis required for respiration. J Clin Invest. 2017;: pubmed publisher
	Tondera C, Laube M, Pietzsch J. Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity. Amino Acids. 2017;49:183-191 pubmed publisher
	Stock A, Kasus Jacobi A, Wren J, Sjoelund V, Prestwich G, Pereira H. The Role of Neutrophil Proteins on the Amyloid Beta-RAGE Axis. PLoS ONE. 2016;11:e0163330 pubmed publisher
	Di Maggio S, Gatti E, Liu J, Bertolotti M, Fritz G, Bianchi M, et al. The Mouse-Specific Splice Variant mRAGE_v4 Encodes a Membrane-Bound RAGE That Is Resistant to Shedding and Does Not Contribute to the Production of Soluble RAGE. PLoS ONE. 2016;11:e0153832 pubmed publisher

product information

brand :

R&D Systems

master code :

AF1145

SKU :

AF1145

product name :

Human/Mouse/Rat RAGE/AGER Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Rat RAGE/AGER Antibody from R&D Systems is a goat polyclonal antibody to AGER. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat RAGE/AGER Antibody has been validated for the following applications: Immunohistochemistry,Blocking,ELISA Development,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Blockade of Receptor-ligand Interaction.

target :

RAGE/AGER

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 0.5-15 ug/mL, Blockade of Receptor-ligand Interaction

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human RAGE, Gln24-Ala344, Accession # Q15109

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human RAGE in direct ELISAs and Western blots.

gene symbol :

AGER

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Human, Mouse, and Rat RAGE antibody by Western Blot.

accessionNumbers :

Q15109

applications :

Blockade of Receptor-ligand Interaction,Blocking,ELISA Development,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry

USD :

509 USD

alt names :

advanced glycosylation end product-specific receptor, AGER, RAGE isoform delta, RAGE isoform sRAGE-delta, Receptor for advanced glycosylation end products, receptor for advanced glycosylation end-products, SCARJ1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage