Mouse Neprilysin/CD10 Antibody | R&D Systems AF1126 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Neprilysin/CD10 Antibody

catalog :

AF1126

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, ELISA, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:500; loading ...; fig 12	Alawi L, Dhakal S, Emberesh S, Sawant H, Hosawi A, Thanekar U, et al. Effects of Angiotensin II Type 1A Receptor on ACE2, Neprilysin and KIM-1 in Two Kidney One Clip (2K1C) Model of Renovascular Hypertension. Front Pharmacol. 2020;11:602985 pubmed publisher
	Kim N, Ju I, Jeon S, Lee Y, Jung M, Gee M, et al. Inhibition of microfold cells ameliorates early pathological phenotypes by modulating microglial functions in Alzheimer's disease mouse model. J Neuroinflammation. 2023;20:282 pubmed publisher
	Williams D, Yan B, Wang H, Negm L, Sackmann C, Verkuyl C, et al. Somatostatin slows Aβ plaque deposition in aged APPNL-F/NL-F mice by blocking Aβ aggregation. Sci Rep. 2023;13:2337 pubmed publisher
	Kisler K, Sagare A, Lazic D, Bazzi S, Lawson E, Hsu C, et al. Anti-malaria drug artesunate prevents development of amyloid-β pathology in mice by upregulating PICALM at the blood-brain barrier. Mol Neurodegener. 2023;18:7 pubmed publisher
	Fitzgerald G, Turiel G, Gorski T, Soro Arnaiz I, Zhang J, Casartelli N, et al. MME+ fibro-adipogenic progenitors are the dominant adipogenic population during fatty infiltration in human skeletal muscle. Commun Biol. 2023;6:111 pubmed publisher
	Qu C, Li Q, Su Z, Ip S, Yuan Q, Xie Y, et al. Nano-Honokiol ameliorates the cognitive deficits in TgCRND8 mice of Alzheimer's disease via inhibiting neuropathology and modulating gut microbiota. J Adv Res. 2022;35:231-243 pubmed publisher
	Wang L, Tang Y, Buckley A, Spurney R. Blockade of the natriuretic peptide clearance receptor attenuates proteinuria in a mouse model of focal segmental glomerulosclerosis. Physiol Rep. 2021;9:e15095 pubmed publisher
	Thanabalasuriar A, Chiang A, Morehouse C, Camara M, Hawkins S, Keller A, et al. PD-L1+ neutrophils contribute to injury-induced infection susceptibility. Sci Adv. 2021;7: pubmed publisher
	Jeon S, Kim N, Ju Y, Gee M, Lee D, Lee J. Phytohormone Abscisic Acid Improves Memory Impairment and Reduces Neuroinflammation in 5xFAD Mice by Upregulation of LanC-Like Protein 2. Int J Mol Sci. 2020;21: pubmed publisher
	Ji H, de Souza A, Bajaj B, Zheng W, Wu X, Speth R, et al. Sex-Specific Modulation of Blood Pressure and the Renin-Angiotensin System by ACE (Angiotensin-Converting Enzyme) 2. Hypertension. 2020;76:478-487 pubmed publisher
	Gee M, Son S, Jeon S, Do J, Kim N, Ju Y, et al. A selective p38α/β MAPK inhibitor alleviates neuropathology and cognitive impairment, and modulates microglia function in 5XFAD mouse. Alzheimers Res Ther. 2020;12:45 pubmed publisher
	Alawi L, Emberesh S, Owuor B, Chodavarapu H, Fadnavis R, El Amouri S, et al. Effect of hyperglycemia and rosiglitazone on renal and urinary neprilysin in db/db diabetic mice. Physiol Rep. 2020;8:e14364 pubmed publisher
	Kim N, Do J, Ju I, Jeon S, Lee J, Oh M. Picrorhiza kurroa Prevents Memory Deficits by Inhibiting NLRP3 Inflammasome Activation and BACE1 Expression in 5xFAD Mice. Neurotherapeutics. 2020;17:189-199 pubmed publisher
	de Dios C, Bartolessis I, Roca Agujetas V, Barbero Camps E, Mari M, Morales A, et al. Oxidative inactivation of amyloid beta-degrading proteases by cholesterol-enhanced mitochondrial stress. Redox Biol. 2019;26:101283 pubmed publisher
	Reichenbach N, Delekate A, Plescher M, Schmitt F, Krauss S, Blank N, et al. Inhibition of Stat3-mediated astrogliosis ameliorates pathology in an Alzheimer's disease model. EMBO Mol Med. 2019;11: pubmed publisher
	Corpas R, Griñan Ferré C, Rodríguez Farré E, Pallas M, Sanfeliu C. Resveratrol Induces Brain Resilience Against Alzheimer Neurodegeneration Through Proteostasis Enhancement. Mol Neurobiol. 2019;56:1502-1516 pubmed publisher
	Kidana K, Tatebe T, Ito K, Hara N, Kakita A, Saito T, et al. Loss of kallikrein-related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice. EMBO Mol Med. 2018;10: pubmed publisher

product information

master code :

AF1126

SKU :

AF1126

product name :

Mouse Neprilysin/CD10 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Neprilysin/CD10 Antibody from R&D Systems is a goat polyclonal antibody to Neprilysin/CD10. This antibody reacts with mouse,rat,transgenic mouse,xenograft. The Mouse Neprilysin/CD10 Antibody has been validated for the following applications: Western Blot,ELISA Capture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation,ELISA Capture (Matched Antibody Pair).

target :

Neprilysin/CD10

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Neprilysin/CD10, Tyr52-Trp750, Accession # AAA37386

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Rat,Transgenic Mouse

specificity :

Detects mouse Neprilysin/CD10 in ELISAs and Western blots. In sandwich immunoassays, less than 35% cross-reactivity with recombinant human (rh) Neprilysin is observed and less than 0.2% cross-reactivity with rhNeprilysin-2 is observed.

gene symbol :

MME

top caption :

Neprilysin/CD10 antibody in Mouse Brain by Immunohistochemistry (IHC-Fr).

accessionNumbers :

AAA37386

applications :

Western Blot,ELISA Capture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunoprecipitation,ELISA Capture (Matched Antibody Pair)

USD :

499 USD

alt names :

Atriopeptidase, CALLA, CALLAmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase), CD10, CD10 antigen, CD10), CD10membrane metallo-endopeptidase variant 1, Common acute lymphocytic leukemia antigen, DKFZp686O16152, EC 3.4.24, EC 3.4.24.11, Enkephalinase, EPN, Leu-19, membrane metallo-endopeptidase, membrane metallo-endopeptidase variant 2, MGC126681, MGC126707, MME, NEPmembrane metallo-endopeptidase (neutral endopeptidase, enkephalinase, CALLA, neprilysin, Neutral endopeptidase, Neutral Endopeptidase 24.11, NKH1, SFE, Skin fibroblast elastase

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage