product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse Adiponectin/Acrp30 Antibody
catalog :
AF1119
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 17
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 4a
Hülser M, Luo Y, Frommer K, Hasseli R, Köhler K, Diller M, et al. Systemic versus local adipokine expression differs in a combined obesity and osteoarthritis mouse model. Sci Rep. 2021;11:17001 pubmed publisher
Fujii K, Fujishima Y, Kita S, Kawada K, Fukuoka K, Sakaue T, et al. Pharmacological HIF-1 activation upregulates extracellular vesicle production synergistically with adiponectin through transcriptional induction and protein stabilization of T-cadherin. Sci Rep. 2024;14:3620 pubmed publisher
Tee J, Vijayakumar U, Shanmugasundaram M, Lam T, Liao W, Yang Y, et al. Isthmin-1 attenuates allergic Asthma by stimulating adiponectin expression and alveolar macrophage efferocytosis in mice. Respir Res. 2023;24:269 pubmed publisher
Fukuoka K, Mineo R, Kita S, Fukuda S, Okita T, Kawada Horitani E, et al. ER stress decreases exosome production through adiponectin/T-cadherin-dependent and -independent pathways. J Biol Chem. 2023;299:105114 pubmed publisher
Okita T, Kita S, Fukuda S, Fukuoka K, Kawada Horitani E, Iioka M, et al. Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling. iScience. 2022;25:105404 pubmed publisher
You J, Sun L, Wang J, Sun F, Wang W, Wang D, et al. Role of Adiponectin-Notch pathway in cognitive dysfunction associated with depression and in the therapeutic effect of physical exercise. Aging Cell. 2021;20:e13387 pubmed publisher
Guan H, Zheng H, Zhang J, Xiang A, Li Y, Zheng H, et al. Secreted frizzled-related protein 4 promotes brown adipocyte differentiation. Exp Ther Med. 2021;21:637 pubmed publisher
Nakamura Y, Kita S, Tanaka Y, Fukuda S, Obata Y, Okita T, et al. Adiponectin Stimulates Exosome Release to Enhance Mesenchymal Stem-Cell-Driven Therapy of Heart Failure in Mice. Mol Ther. 2020;28:2203-2219 pubmed publisher
Quiroga D, Miquet J, Gonzalez L, Sotelo A, Muñoz M, Geraldes P, et al. Mice lacking angiotensin type 2 receptor exhibit a sex-specific attenuation of insulin sensitivity. Mol Cell Endocrinol. 2019;498:110587 pubmed publisher
Quiroga D, Muñoz M, Gil C, Pffeifer M, Toblli J, Steckelings U, et al. Chronic administration of the angiotensin type 2 receptor agonist C21 improves insulin sensitivity in C57BL/6 mice. Physiol Rep. 2018;6:e13824 pubmed publisher
Sun F, Lei Y, You J, Li C, Sun L, GARZA J, et al. Adiponectin modulates ventral tegmental area dopamine neuron activity and anxiety-related behavior through AdipoR1. Mol Psychiatry. 2019;24:126-144 pubmed publisher
Obata Y, Kita S, Koyama Y, Fukuda S, Takeda H, Takahashi M, et al. Adiponectin/T-cadherin system enhances exosome biogenesis and decreases cellular ceramides by exosomal release. JCI Insight. 2018;3: pubmed publisher
Shin J, Fukuhara A, Onodera T, Kita S, Yokoyama C, Otsuki M, et al. SDF-1 Is an Autocrine Insulin-Desensitizing Factor in Adipocytes. Diabetes. 2018;67:1068-1078 pubmed publisher
Hu C, Keen H, Lu K, Liu X, Wu J, Davis D, et al. Retinol-binding protein 7 is an endothelium-specific PPARγ cofactor mediating an antioxidant response through adiponectin. JCI Insight. 2017;2:e91738 pubmed publisher
Fukuda S, Kita S, Obata Y, Fujishima Y, Nagao H, Masuda S, et al. The unique prodomain of T-cadherin plays a key role in adiponectin binding with the essential extracellular cadherin repeats 1 and 2. J Biol Chem. 2017;292:7840-7849 pubmed publisher
Munoz M, Burghi V, Miquet J, Cervino I, Quiroga D, Mazziotta L, et al. Chronic blockade of the AT2 receptor with PD123319 impairs insulin signaling in C57BL/6 mice. Peptides. 2017;88:37-45 pubmed publisher
Guo M, Li C, Lei Y, Xu S, Zhao D, Lu X. Role of the adipose PPAR?-adiponectin axis in susceptibility to stress and depression/anxiety-related behaviors. Mol Psychiatry. 2017;22:1056-1068 pubmed publisher
product information
master code :
AF1119
SKU :
AF1119
product name :
Mouse Adiponectin/Acrp30 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse Adiponectin/Acrp30 Antibody from R&D Systems is a goat polyclonal antibody to Adiponectin/Acrp30. This antibody reacts with human,mouse,transgenic mouse. The Mouse Adiponectin/Acrp30 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
Adiponectin/Acrp30
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Adiponectin/Acrp30, Glu18-Asn247, Accession # Q60994
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects mouse Adiponectin/Acrp30 in direct ELISAs and Western blots.
gene symbol :
ADIPOQ
top caption :
Adiponectin/Acrp30 antibody in ST-2 mouse bone marrow-derived stromal cell line differentiated to adipocytes by Immunocytochemistry (ICC).
accessionNumbers :
Q60994
applications :
Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
509 USD
alt names :
ACDC, Acrp30, ACRP30ADPN, adipocyte, C1Q and collagen domain containing, adiponectin, adiponectin, C1Q and collagen domain containing, AdipoQ, ADIPQTL1, apM-1, ApM1, APM1APM-1, C1q and collagen domain-containing protein, GBP28, GBP28apM1, Gelatin-binding protein
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.