Human Dkk-3 Antibody | R&D Systems AF1118 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Dkk-3 Antibody

catalog :

AF1118

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 4

Reference
Martín Flores N, Podpolny M, McLeod F, Workman I, Crawford K, Ivanov D, et al. Downregulation of Dickkopf-3, a Wnt antagonist elevated in Alzheimer's disease, restores synapse integrity and memory in a disease mouse model. elife. 2024;12: pubmed publisher
Nguyen Q, Park H, Lee T, Choi K, Park J, Kim D, et al. DKK3, Downregulated in Invasive Epithelial Ovarian Cancer, Is Associated with Chemoresistance and Enhanced Paclitaxel Susceptibility via Inhibition of the β-Catenin-P-Glycoprotein Signaling Pathway. Cancers (Basel). 2022;14: pubmed publisher
Chiyonobu N, Shimada S, Akiyama Y, Mogushi K, Itoh M, Akahoshi K, et al. Fatty Acid Binding Protein 4 (FABP4) Overexpression in Intratumoral Hepatic Stellate Cells within Hepatocellular Carcinoma with Metabolic Risk Factors. Am J Pathol. 2018;188:1213-1224 pubmed publisher
Lorsy E, Topuz A, Geisler C, Stahl S, Garczyk S, von Stillfried S, et al. Loss of Dickkopf 3 Promotes the Tumorigenesis of Basal Breast Cancer. PLoS ONE. 2016;11:e0160077 pubmed publisher

product information

brand :

R&D Systems

master code :

AF1118

SKU :

AF1118

product name :

Human Dkk-3 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human Dkk-3 Antibody from R&D Systems is a goat polyclonal antibody to Dkk-3. This antibody reacts with human,mouse. The Human Dkk-3 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,ELISA.

target :

Dkk-3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

ELISA, Immunohistochemistry 3-15 ug/mL

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Dkk-3, Ala22-Ile350, Accession # Q9UBP4

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects human Dkk-3 in direct ELISAs. In direct ELISAs, approximately 35% cross-reactivity with recombinant mouse Dkk-3 is observed.

gene symbol :

DKK3

accessionNumbers :

Q9UBP4

applications :

ELISA,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry

USD :

489 USD

alt names :

dickkopf (Xenopus laevis) homolog 3, dickkopf 3, dickkopf homolog 3 (Xenopus laevis), Dickkopf-3, dickkopf-related protein 3, Dkk3, Dkk-3, hDkk-3, regulated in glioma, REIC, REICdkk-3, RIG, RIG-like 5-6, RIG-like 7-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage