Mouse Netrin-1 Antibody | R&D Systems AF1109 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Netrin-1 Antibody

catalog :

AF1109

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 10

Reference
Kathiriya I, Dominguez M, Rao K, Muncie Vasic J, Devine W, Hu K, et al. A disrupted compartment boundary underlies abnormal cardiac patterning and congenital heart defects. bioRxiv. 2024;: pubmed publisher
Alvarez S, Gupta S, Honeychurch K, Mercado Ayon Y, Kawaguchi R, Butler S. Netrin1 patterns the dorsal spinal cord through modulation of Bmp signaling. bioRxiv. 2023;: pubmed publisher
Ramalingam P, Gutkin M, Poulos M, Tillery T, Doughty C, Winiarski A, et al. Restoring bone marrow niche function rejuvenates aged hematopoietic stem cells by reactivating the DNA Damage Response. Nat Commun. 2023;14:2018 pubmed publisher
Xia X, Mao Z, Wang W, Ma J, Tian J, Wang S, et al. Netrin-1 Promotes the Immunosuppressive Activity of MDSCs in Colorectal Cancer. Cancer Immunol Res. 2023;11:600-613 pubmed publisher
Chan E, Ge Y, So Y, Bai Y, Liu L, Wang Y. Allosteric potentiation of GABAA receptor single-channel conductance by netrin-1 during neuronal-excitation-induced inhibitory synaptic homeostasis. Cell Rep. 2022;41:111584 pubmed publisher
Boyé K, Geraldo L, Furtado J, Pibouin Fragner L, Poulet M, Kim D, et al. Endothelial Unc5B controls blood-brain barrier integrity. Nat Commun. 2022;13:1169 pubmed publisher
Xiao M, Hu Z, Jiang H, Li C, Guo H, Fang W, et al. The expression of Netrin-1 in the MIA-induced osteoarthritic temporomandibular joint in mice. Sci Rep. 2021;11:15695 pubmed publisher
Morcom L, Gobius I, Marsh A, Suárez R, Lim J, Bridges C, et al. DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. elife. 2021;10: pubmed publisher
Yamahara K, Nakagawa T, Ito J, Kinoshita K, Omori K, Yamamoto N. Netrin 1 mediates protective effects exerted by insulin-like growth factor 1 on cochlear hair cells. Neuropharmacology. 2017;119:26-39 pubmed publisher
Lahlali T, Plissonnier M, Romero López C, Michelet M, Ducarouge B, Berzal Herranz A, et al. Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response. Cell Mol Gastroenterol Hepatol. 2016;2:281-301.e9 pubmed publisher

product information

master code :

AF1109

SKU :

AF1109

product name :

Mouse Netrin-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Netrin-1 Antibody from R&D Systems is a goat polyclonal antibody to Netrin-1. This antibody reacts with human,mouse. The Mouse Netrin-1 Antibody has been validated for the following applications: Neutralization,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Blockade of Receptor-ligand Interaction.

target :

Netrin-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse Netrin-1, Val22-Ala603, Accession # AAC52971

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse

specificity :

Detects mouse Netrin-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 10% cross-reactivity with recombinant chicken (rch) Netrin-1 and recombinant human Netrin-1 is observed and less than 1% cross-reactivity with recombinant mouse (rm) Netrin-G1a and rmNetrin-4 is observed.

gene symbol :

NTN1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human Netrin-1 by Western Blot

accessionNumbers :

AAC52971

applications :

Neutralization,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Blockade of Receptor-ligand Interaction

USD :

479 USD

alt names :

netrin 1, netrin-1, Netrin1, NTN1, NTN1Lnetrin 1, mouse, homolog of

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage