product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Endoglin/CD105 Antibody
catalog :
AF1097
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 17
Reference
Giorello M, Martinez L, Borzone F, Padin M, Mora M, Sevic I, et al. CD105 expression in cancer-associated fibroblasts: a biomarker for bone metastasis in early invasive ductal breast cancer patients. Front Cell Dev Biol. 2023;11:1250869 pubmed publisher
Gerrits T, Brouwer I, Dijkstra K, Wolterbeek R, Bruijn J, Scharpfenecker M, et al. Endoglin Is an Important Mediator in the Final Common Pathway of Chronic Kidney Disease to End-Stage Renal Disease. Int J Mol Sci. 2022;24: pubmed publisher
Mendez P, Obendorf L, Jatzlau J, Burdzinski W, Reichenbach M, Nageswaran V, et al. Atheroprone fluid shear stress-regulated ALK1-Endoglin-SMAD signaling originates from early endosomes. BMC Biol. 2022;20:210 pubmed publisher
Mitroi D, Tian M, Kawaguchi R, Lowry W, Carmichael S. Single-nucleus transcriptome analysis reveals disease- and regeneration-associated endothelial cells in white matter vascular dementia. J Cell Mol Med. 2022;26:3183-3195 pubmed publisher
Singh C, Wang H. Reversing pathology in a preclinical model of Alzheimer's disease by hacking cerebrovascular neoangiogenesis with advanced cancer therapeutics. EBioMedicine. 2021;71:103503 pubmed publisher
Galaris G, Montagne K, Thalgott J, Goujon G, van den Driesche S, Martin S, et al. Thresholds of Endoglin Expression in Endothelial Cells Explains Vascular Etiology in Hereditary Hemorrhagic Telangiectasia Type 1. Int J Mol Sci. 2021;22: pubmed publisher
Korpershoek J, Rikkers M, de Windt T, Tryfonidou M, Saris D, Vonk L. Selection of Highly Proliferative and Multipotent Meniscus Progenitors through Differential Adhesion to Fibronectin: A Novel Approach in Meniscus Tissue Engineering. Int J Mol Sci. 2021;22: pubmed publisher
Kenswil K, Pisterzi P, Sanchez Duffhues G, van Dijk C, Lolli A, Knuth C, et al. Endothelium-derived stromal cells contribute to hematopoietic bone marrow niche formation. Cell Stem Cell. 2021;28:653-670.e11 pubmed publisher
Gerrits T, Zandbergen M, Wolterbeek R, Bruijn J, Baelde H, Scharpfenecker M. Endoglin Promotes Myofibroblast Differentiation and Extracellular Matrix Production in Diabetic Nephropathy. Int J Mol Sci. 2020;21: pubmed publisher
Maring J, Lodder K, Mol E, Verhage V, Wiesmeijer K, Dingenouts C, et al. Cardiac Progenitor Cell-Derived Extracellular Vesicles Reduce Infarct Size and Associate with Increased Cardiovascular Cell Proliferation. J Cardiovasc Transl Res. 2019;12:5-17 pubmed publisher
Zhang Q, Yi D, Xue B, Wen W, Lu Y, Abdelmaksou A, et al. CD90 determined two subpopulations of glioma-associated mesenchymal stem cells with different roles in tumour progression. Cell Death Dis. 2018;9:1101 pubmed publisher
Moffett H, Coon M, Radtke S, Stephan S, McKnight L, Lambert A, et al. Hit-and-run programming of therapeutic cytoreagents using mRNA nanocarriers. Nat Commun. 2017;8:389 pubmed publisher
Garcia Hernandez M, Uribe Uribe N, Espinosa González R, Kast W, Khader S, Rangel Moreno J. A Unique Cellular and Molecular Microenvironment Is Present in Tertiary Lymphoid Organs of Patients with Spontaneous Prostate Cancer Regression. Front Immunol. 2017;8:563 pubmed publisher
Jin Y, Muhl L, Burmakin M, Wang Y, Duchez A, Betsholtz C, et al. Endoglin prevents vascular malformation by regulating flow-induced cell migration and specification through VEGFR2 signalling. Nat Cell Biol. 2017;19:639-652 pubmed publisher
Powner M, Sim D, Zhu M, Nobre Cardoso J, Jones R, Syed A, et al. Evaluation of Nonperfused Retinal Vessels in Ischemic Retinopathy. Invest Ophthalmol Vis Sci. 2016;57:5031-5037 pubmed publisher
Bolnick J, Kohan Ghadr H, Fritz R, Bolnick A, Kilburn B, Diamond M, et al. Altered Biomarkers in Trophoblast Cells Obtained Noninvasively Prior to Clinical Manifestation of Perinatal Disease. Sci Rep. 2016;6:32382 pubmed publisher
Klein S, Hinüber C, Hittatiya K, Schierwagen R, Uschner F, Strassburg C, et al. Novel Rat Model of Repetitive Portal Venous Embolization Mimicking Human Non-Cirrhotic Idiopathic Portal Hypertension. PLoS ONE. 2016;11:e0162144 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1097
SKU :
AF1097
product name :
Human Endoglin/CD105 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human Endoglin/CD105 Antibody from R&D Systems is a goat polyclonal antibody to Endoglin/CD105. This antibody reacts with human,mouse. The Human Endoglin/CD105 Antibody has been validated for the following applications: IHC-,Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Simple Western,CyTOF-ready,Knockout Validated.
target :
Endoglin/CD105
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.25 ug/mL, Simple Western 20 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 5-15 ug/mL, Immunocytochemistry 5-15 ug/mL, CyTOF-ready, Knockout Validated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Endoglin/CD105, Glu26-Gly586, Accession # Q5T9B9
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse
specificity :
Detects human Endoglin in direct ELISAs and Western blots.
gene symbol :
ENG
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Human Endoglin/CD105 antibody by Western Blot.
accessionNumbers :
Q5T9B9
applications :
Simple Western,CyTOF-ready,Knockout Validated,IHC-,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
519 USD
alt names :
CD105, CD105 antigen, endoglin, ENDOsler-Rendu-Weber syndrome 1, ENG, HHT1FLJ41744, ORW, ORW1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.