product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse Neogenin Antibody
catalog :
AF1079
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, chicken
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:200; loading ...; fig 5b
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3d
  • western blot; mouse; fig s4a
Robinson R, Griffiths S, van de Haar L, Malinauskas T, van Battum E, Zelina P, et al. Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell. 2021;184:2103-2120.e31 pubmed publisher
Sempert K, Shohayeb B, Lanoue V, O Brien E, Flores C, Cooper H. RGMa and Neogenin control dendritic spine morphogenesis via WAVE Regulatory Complex-mediated actin remodeling. Front Mol Neurosci. 2023;16:1253801 pubmed publisher
Untiveros G, Raskind A, Linares L, Dotti A, Strizzi L. Netrin-1 Stimulates Migration of Neogenin Expressing Aggressive Melanoma Cells. Int J Mol Sci. 2022;23: pubmed publisher
Guaiquil V, Xiao C, Lara D, Dimailig G, Zhou Q. Expression of axon guidance ligands and their receptors in the cornea and trigeminal ganglia and their recovery after corneal epithelium injury. Exp Eye Res. 2022;219:109054 pubmed publisher
Apóstolo N, Smukowski S, Vanderlinden J, Condomitti G, Rybakin V, Ten Bos J, et al. Synapse type-specific proteomic dissection identifies IgSF8 as a hippocampal CA3 microcircuit organizer. Nat Commun. 2020;11:5171 pubmed publisher
Hadi T, Boytard L, Silvestro M, Alebrahim D, Jacob S, Feinstein J, et al. Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells. Nat Commun. 2018;9:5022 pubmed publisher
Schlegel M, Körner A, Kaussen T, Knausberg U, Gerber C, Hansmann G, et al. Inhibition of neogenin fosters resolution of inflammation and tissue regeneration. J Clin Invest. 2018;128:4711-4726 pubmed publisher
Liu J, Reggiani J, Laboulaye M, Pandey S, Chen B, Rubenstein J, et al. Tbr1 instructs laminar patterning of retinal ganglion cell dendrites. Nat Neurosci. 2018;21:659-670 pubmed publisher
Frýdlová J, Prikryl P, Truksa J, Falke L, Du X, Gurieva I, et al. Effect of Erythropoietin, Iron Deficiency and Iron Overload on Liver Matriptase-2 (TMPRSS6) Protein Content in Mice and Rats. PLoS ONE. 2016;11:e0148540 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1079
SKU :
AF1079
product name :
Human/Mouse Neogenin Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse Neogenin Antibody from R&D Systems is a goat polyclonal antibody to Neogenin. This antibody reacts with avian - chicken,human,mouse,primate - chlorocebus pygerythrus (vervet monkey),transgenic mouse. The Human/Mouse Neogenin Antibody has been validated for the following applications: Immunohistochemistry,Apoptosis,Efferocytosis Assay,Stimulation,Transcriptional Analysis,Western Blot,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western,Blockade of Receptor-ligand Interaction.
target :
Neogenin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, Simple Western 10 ug/mL, Immunohistochemistry 5-15 ug/mL, Blockade of Receptor-ligand Interaction
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse Neogenin, Ala42-Ile1033 (Asp442-Leu461 del), Accession # NP_032710
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Avian - Chicken,Human,Mouse,Primate - Chlorocebus pygerythrus (Vervet Monkey),Transgenic Mouse
specificity :
Detects human and mouse Neogenin in direct ELISAs and Western blots.
gene symbol :
NEO1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human and Mouse Neogenin antibody by Western Blot.
accessionNumbers :
NP_032710
applications :
Simple Western,Blockade of Receptor-ligand Interaction,Apoptosis,Efferocytosis Assay,Stimulation,Transcriptional Analysis,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization
USD :
509 USD
alt names :
HsT17534, IGDCC2DKFZp547B146, Immunoglobulin superfamily DCC subclass member 2, NEO, NEO1, neogenin, neogenin (chicken) homolog 1, neogenin 1, neogenin homolog 1, NGN, NGNDKFZp547A066
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.