Mouse JAM-A Antibody | R&D Systems AF1077 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse JAM-A Antibody

catalog :

AF1077

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Rizzo G, Pineda Chavez S, Vandenkoornhuyse E, C xe1 rdenas Rinc xf3 n C, Cento V, Garlatti V, et al. Pomegranate Extract Affects Gut Biofilm Forming Bacteria and Promotes Intestinal Mucosal Healing Regulating the Crosstalk between Epithelial Cells and Intestinal Fibroblasts. Nutrients. 2023;15: pubmed publisher
Fan S, Smith M, Keeney J, O Leary M, Nusrat A, Parkos C. JAM-A signals through the Hippo pathway to regulate intestinal epithelial proliferation. iScience. 2022;25:104316 pubmed publisher
Yamani A, Wu D, Ahrens R, Waggoner L, Noah T, García Hernández V, et al. Dysregulation of intestinal epithelial CFTR-dependent Cl- ion transport and paracellular barrier function drives gastrointestinal symptoms of food-induced anaphylaxis in mice. Mucosal Immunol. 2021;14:135-143 pubmed publisher
Azcutia V, Kelm M, Luissint A, Boerner K, Flemming S, Quirós M, et al. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo. Mucosal Immunol. 2020;: pubmed publisher
Luissint A, Williams H, Kim W, Flemming S, Azcutia V, Hilgarth R, et al. Macrophage-dependent neutrophil recruitment is impaired under conditions of increased intestinal permeability in JAM-A-deficient mice. Mucosal Immunol. 2019;12:668-678 pubmed publisher
Flemming S, Luissint A, Nusrat A, Parkos C. Analysis of leukocyte transepithelial migration using an in vivo murine colonic loop model. JCI Insight. 2018;3: pubmed publisher
Chopyk D, Kumar P, Raeman R, Liu Y, Smith T, Anania F. Dysregulation of junctional adhesion molecule-A contributes to ethanol-induced barrier disruption in intestinal epithelial cell monolayers. Physiol Rep. 2017;5: pubmed publisher
Hintermann E, Bayer M, Ehser J, Aurrand Lions M, Pfeilschifter J, Imhof B, et al. Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis. Cell Adh Migr. 2016;10:419-33 pubmed publisher

product information

master code :

AF1077

SKU :

AF1077

product name :

Mouse JAM-A Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse JAM-A Antibody from R&D Systems is a goat polyclonal antibody to JAM-A. This antibody reacts with mouse. The Mouse JAM-A Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development,Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair).

target :

JAM-A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse JAM-A, Lys27-Ala242, Accession # O88792

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse

specificity :

Detects mouse JAM-A in ELISAs and Western blots. In sandwich immunoassays, less than 1% cross-reactivity with recombinant human JAM-A, recombinant mouse (rm) JAM-B, and rmJAM-C is observed.

gene symbol :

F11R

accessionNumbers :

O88792

applications :

Immunohistochemistry,ELISA Development,Flow Cytometry,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair)

USD :

459 USD

alt names :

CD321, CD321 antigen, F11 receptor, F11R, JAM-1, JAM1CD321, JAMA, JAM-A, JCAMJAM, Junctional adhesion molecule 1Platelet F11 receptor, junctional adhesion molecule A, PAM-1, PAM-1KAT, Platelet adhesion molecule 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage