Human Siglec-5/Siglec-14 Antibody | R&D Systems AF1072 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Siglec-5/Siglec-14 Antibody

catalog :

AF1072

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, bovine

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 4

Reference
Tseng Y, Chang C, Chang Y. Novel Virulence Role of Pneumococcal NanA in Host Inflammation and Cell Death Through the Activation of Inflammasome and the Caspase Pathway. Front Cell Infect Microbiol. 2021;11:613195 pubmed publisher
Vijayan M, Lee C, Wong V, Wang X, Bai K, Wu J, et al. Decidual glycodelin-A polarizes human monocytes into a decidual macrophage-like phenotype through Siglec-7. J Cell Sci. 2020;133: pubmed publisher
Alkhodair K, Almhanna H, McGetrick J, Gedair S, Gallagher M, Fernandez Fuertes B, et al. Siglec expression on the surface of human, bull and ram sperm. Reproduction. 2018;155:361-371 pubmed publisher
Pepin M, Mezouar S, Pegon J, Muczynski V, Adam F, Bianchini E, et al. Soluble Siglec-5 associates to PSGL-1 and displays anti-inflammatory activity. Sci Rep. 2016;6:37953 pubmed publisher

product information

master code :

AF1072

SKU :

AF1072

product name :

Human Siglec-5/Siglec-14 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Siglec-5/Siglec-14 Antibody from R&D Systems is a goat polyclonal antibody to Siglec-5/Siglec-14. This antibody reacts with bovine,human,mouse,ovine,rat. The Human Siglec-5/Siglec-14 Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry,Immunocytochemistry,Flow Cytometry,CyTOF-ready.

target :

Siglec-5/Siglec-14

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Siglec-5, Glu17-Thr434, Accession # O15389

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Bovine,Human,Mouse,Ovine,Rat

specificity :

Detects human Siglec-5/14 in direct ELISAs and Western blots. In direct ELISAs, approximately 5% cross-reactivity with recombinant human (rh) Siglec-7 and rhSiglec-9 is observed and less than 1% cross-reactivity with rhSiglec-2 and rhSiglec-3 is observed.

gene symbol :

SIGLEC5

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Adhesion Mediated by Siglec-5 and Neutralization by Human Siglec-5/14 Antibody.

accessionNumbers :

O15389

applications :

Western Blot,Neutralization,Immunohistochemistry,Immunocytochemistry,Flow Cytometry,CyTOF-ready

USD :

479 USD

alt names :

CD170, CD170;CD33L2;OBBP2;OB-BP2;Sialic acid-binding Ig-like lectin 5;SIGLEC5;SIGLEC-5, CD33L2, OBBP2, Siglec14, Siglec5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage