product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat Growth Hormone Antibody
catalog :
AF1067
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, neutralization, immunohistochemistry - paraffin section
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; fig 3m
Duan S, Sawyer T, Sontz R, Wieland B, Diaz A, Merchant J. GFAP-directed Inactivation of Men1 Exploits Glial Cell Plasticity in Favor of Neuroendocrine Reprogramming. Cell Mol Gastroenterol Hepatol. 2022;14:1025-1051 pubmed publisher
Liu K, Hunter T, Taverner A, Yin K, MacKay J, Colebrook K, et al. GRP75 as a functional element of cholix transcytosis. Tissue Barriers. 2023;11:2039003 pubmed publisher
Akiba K, Hasegawa Y, Katoh Fukui Y, Terao M, Takada S, Hasegawa T, et al. POU1F1/Pou1f1 c.143-83A > G Variant Disrupts the Branch Site in Pre-mRNA and Leads to Dwarfism. Endocrinology. 2022;164: pubmed publisher
Chesnokova V, Zonis S, Apostolou A, Estrada H, Knott S, Wawrowsky K, et al. Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage. Cell Rep. 2021;37:110068 pubmed publisher
Li R, Laurent F, Taverner A, MacKay J, De Bank P, Mrsny R. Intestinal Transcytosis of a Protein Cargo and Nanoparticles Mediated by a Non-Toxic Form of Pseudomonas aeruginosa Exotoxin A. Pharmaceutics. 2021;13: pubmed publisher
Vélez E, Unniappan S. Nesfatin-1 and nesfatin-1-like peptide suppress growth hormone synthesis via the AC/PKA/CREB pathway in mammalian somatotrophs. Sci Rep. 2020;10:16686 pubmed publisher
Abboud D, Daly A, Dupuis N, Bahri M, Inoue A, Chevigné A, et al. GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11. Nat Commun. 2020;11:4752 pubmed publisher
Taverner A, MacKay J, Laurent F, Hunter T, Liu K, Mangat K, et al. Cholix protein domain I functions as a carrier element for efficient apical to basal epithelial transcytosis. Tissue Barriers. 2020;8:1710429 pubmed publisher
Takesue Y, Wei F, Fukuda H, Tanoue Y, Yamamoto T, Chujo T, et al. Regulation of growth hormone biosynthesis by Cdk5 regulatory subunit associated protein 1-like 1 (CDKAL1) in pituitary adenomas. Endocr J. 2019;: pubmed publisher
Sasanuma H, Nakata M, Parmila K, Nakae J, Yada T. PDK1-FoxO1 pathway in AgRP neurons of arcuate nucleus promotes bone formation via GHRH-GH-IGF1 axis. Mol Metab. 2017;6:428-439 pubmed publisher
Recouvreux M, Wu J, Gao A, Zonis S, Chesnokova V, Bhowmick N, et al. Androgen Receptor Regulation of Local Growth Hormone in Prostate Cancer Cells. Endocrinology. 2017;158:2255-2268 pubmed publisher
Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed publisher
product information
brand :
R&D Systems
master code :
AF1067
SKU :
AF1067
product name :
Human/Mouse/Rat Growth Hormone Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human/Mouse/Rat Growth Hormone Antibody from R&D Systems is a goat polyclonal antibody to Growth Hormone. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat Growth Hormone Antibody has been validated for the following applications: Electrochemiluminescent Assay,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,ELISA.
target :
Growth Hormone
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.5 ug/mL, ELISA, Immunohistochemistry 5-15 ug/mL, Neutralization 1.5-7.5 ng/mL
host :
Goat
immunogen :
E. coli -derived recombinant human Growth Hormone, Phe27-Phe217, Accession # CAA23779
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects human Growth Hormone in direct ELISAs and Western blots.
gene symbol :
GH1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Human, Mouse, and Rat Growth Hormone antibody by Western Blot.
accessionNumbers :
CAA23779
applications :
ELISA,Electrochemiluminescent Assay,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Neutralization
USD :
489 USD
alt names :
GH1, GHB5, GHIGHD1B, GHN, GH-N, GHNGrowth hormone, GH-Nsomatotropin, growth hormone 1Pituitary growth hormone, hGH-N, IGHD1A, IGHD2, Somatotropin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.