Mouse/Rat Notch-1 Antibody | R&D Systems AF1057 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse/Rat Notch-1 Antibody

catalog :

AF1057

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 7

Reference
Giraldo E, Bonilla P, Mellado M, García Manau P, Rodó C, Alastrue A, et al. Transplantation of Human-Fetal-Spinal-Cord-Derived NPCs Primed with a Polyglutamate-Conjugated Rho/Rock Inhibitor in Acute Spinal Cord Injury. Cells. 2022;11: pubmed publisher
Filipovi x107 M, Flegar D, x160 u x107 ur A, x160 isl D, Kavazovi x107 I, Antica M, et al. Inhibition of Notch Signaling Stimulates Osteoclastogenesis From the Common Trilineage Progenitor Under Inflammatory Conditions. Front Immunol. 2022;13:902947 pubmed publisher
Bonilla P, Hernandez J, Giraldo E, González Pérez M, Alastrue Agudo A, Elkhenany H, et al. Human-Induced Neural and Mesenchymal Stem Cell Therapy Combined with a Curcumin Nanoconjugate as a Spinal Cord Injury Treatment. Int J Mol Sci. 2021;22: pubmed publisher
Davis R, Pahl K, Datto N, Smith S, Shawber C, Caron K, et al. Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations. Sci Rep. 2018;8:17987 pubmed publisher
Verma M, Asakura Y, Murakonda B, Pengo T, Latroche C, Chazaud B, et al. Muscle Satellite Cell Cross-Talk with a Vascular Niche Maintains Quiescence via VEGF and Notch Signaling. Cell Stem Cell. 2018;23:530-543.e9 pubmed publisher
Shaya O, Binshtok U, Hersch M, Rivkin D, Weinreb S, Amir Zilberstein L, et al. Cell-Cell Contact Area Affects Notch Signaling and Notch-Dependent Patterning. Dev Cell. 2017;40:505-511.e6 pubmed publisher
Pignatelli J, Bravo Cordero J, Roh Johnson M, Gandhi S, Wang Y, Chen X, et al. Macrophage-dependent tumor cell transendothelial migration is mediated by Notch1/MenaINV-initiated invadopodium formation. Sci Rep. 2016;6:37874 pubmed publisher

product information

master code :

AF1057

SKU :

AF1057

product name :

Mouse/Rat Notch-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse/Rat Notch-1 Antibody from R&D Systems is a goat polyclonal antibody to Notch-1. This antibody reacts with human,mouse,rat. The Mouse/Rat Notch-1 Antibody has been validated for the following applications: Neutralization,Bioassay,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry,Blockade of Receptor-ligand Interaction,CyTOF-ready.

target :

Notch-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant rat Notch-1, Arg20-Glu488 (Ala208Thr, Asp334Glu), Accession # Q07008

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects rat Notch-1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant rat Notch-2 and recombinant mouse Notch-3 is observed.

gene symbol :

NOTCH1

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Notch-1 antibody in Rat Cortical Stem Cells by Immunocytochemistry (ICC).

accessionNumbers :

Q07008

applications :

Neutralization,Bioassay,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,Immunohistochemistry,Blockade of Receptor-ligand Interaction,CyTOF-ready

USD :

469 USD

alt names :

EC 2.1.2.11, EC 3.4.21.68, hN1, Notch (Drosophila) homolog 1 (translocation-associated), notch 1Notch homolog 1, translocation-associated (Drosophila), Notch homolog 1, translocation-associated, Notch1, TAN1, TAN1neurogenic locus notch homolog protein 1, Translocation-associated notch protein TAN-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage