Human HAI-1 Antibody | R&D Systems AF1048 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human HAI-1 Antibody

catalog :

AF1048

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 5

Reference
Hatzold J, Nett V, Brantsch S, Zhang J, Armistead J, Wessendorf H, et al. Matriptase-dependent epidermal pre-neoplasm in zebrafish embryos caused by a combination of hypotonic stress and epithelial polarity defects. PLoS Genet. 2023;19:e1010873 pubmed publisher
Wu C, Lu M, Feng X, Nakato G, Udey M. Matriptase Cleaves EpCAM and TROP2 in Keratinocytes, Destabilizing Both Proteins and Associated Claudins. Cells. 2020;9: pubmed publisher
Du X, Wu L, Ur Rahman M, Teng X, Teng L, Ye J, et al. Promoter Hypomethylation Is Responsible for Upregulated Expression of HAI-1 in Hepatocellular Carcinoma. Dis Markers. 2019;2019:9175215 pubmed publisher
Ishikawa T, Kimura Y, Hirano H, Higashi S. Matrix metalloproteinase-7 induces homotypic tumor cell aggregation via proteolytic cleavage of the membrane-bound Kunitz-type inhibitor HAI-1. J Biol Chem. 2017;292:20769-20784 pubmed publisher
Murray A, Varela F, Hyland T, Schoenbeck A, White J, Tanabe L, et al. Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization. J Biol Chem. 2017;292:14867-14884 pubmed publisher

product information

master code :

AF1048

SKU :

AF1048

product name :

Human HAI-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human HAI-1 Antibody from R&D Systems is a goat polyclonal antibody to HAI-1/HGFA Inhibitor 1. This antibody reacts with human. The Human HAI-1 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Simple Western.

target :

HAI-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

Mouse myeloma cell line NS0-derived recombinant human HAI-1, Pro37-Glu449, Accession # NP_003701

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human

specificity :

Detects human HAI-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant mouse HAI-1 is observed and less than 1% cross-reactivity with recombinant human HAI-2 is observed.

gene symbol :

SPINT1

top caption :

Detection of Human HAI-1 antibody by Western Blot.

accessionNumbers :

NP_003701

applications :

Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry,Simple Western

USD :

469 USD

alt names :

HAI, HAI1, HAI-1, hepatocyte growth factor activator inhibitor 1, Hepatocyte growth factor activator inhibitor type 1, kunitz-type protease inhibitor 1, MANSC2, serine peptidase inhibitor, Kunitz type 1, serine protease inhibitor, Kunitz type 1, SPINT1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage