Human ADAM8 Ectodomain Antibody | R&D Systems AF1031 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human ADAM8 Ectodomain Antibody

catalog :

AF1031

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 2a	Jaworek C, Verel Yilmaz Y, Driesch S, Ostgathe S, Cook L, Wagner S, et al. Cohort Analysis of ADAM8 Expression in the PDAC Tumor Stroma. J Pers Med. 2021;11: pubmed publisher
	Mineva N, Pianetti S, Das S, Srinivasan S, Billiald N, Sonenshein G. A Novel Class of Human ADAM8 Inhibitory Antibodies for Treatment of Triple-Negative Breast Cancer. Pharmaceutics. 2024;16: pubmed publisher
	Mi Z, Kuo M, Kuo P. RNA Aptamer Targeting of Adam8 in Cancer Growth and Metastasis. Cancers (Basel). 2023;15: pubmed publisher
	Conrad C, Yildiz D, Cleary S, Margraf A, Cook L, Schlomann U, et al. ADAM8 signaling drives neutrophil migration and ARDS severity. JCI Insight. 2022;7: pubmed publisher
	Li Y, Guo S, Zhao K, Conrad C, Driescher C, Rothbart V, et al. ADAM8 affects glioblastoma progression by regulating osteopontin-mediated angiogenesis. Biol Chem. 2021;402:195-206 pubmed publisher
	Theodorou K, van der Vorst E, Gijbels M, Wolfs I, Jeurissen M, Theelen T, et al. Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression. Sci Rep. 2017;7:11670 pubmed publisher

product information

master code :

AF1031

SKU :

AF1031

product name :

Human ADAM8 Ectodomain Antibody

unit size :

100 ug (also 25 ug)

description :

The Human ADAM8 Ectodomain Antibody from R&D Systems is a goat polyclonal antibody to ADAM8. This antibody reacts with human,n/a. The Human ADAM8 Ectodomain Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Native SDS-PAGE,Immunoprecipitation,Neutralization,Immunohistochemistry,Immunocytochemistry.

target :

ADAM8

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human ADAM8 Ectodomain, Glu158-Ser653, Accession # P78325

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,N/A

specificity :

Detects human ADAM8 Ectodomain in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse ADAM8 is observed and less than 1% cross-reactivity with recombinant human (rh) ADAM12, rhADAM19, and rhADAM33 is observed.

gene symbol :

ADAM8

top caption :

ADAM8 antibody in Human PBMCs by Immunocytochemistry (ICC).

accessionNumbers :

P78325

applications :

Flow Cytometry,Native SDS-PAGE,Immunoprecipitation,Western Blot,Neutralization,Immunohistochemistry,Immunocytochemistry

USD :

499 USD

alt names :

a disintegrin and metalloproteinase domain 8, ADAM 8, ADAM metallopeptidase domain 8, CD156a, CD156a antigen, CD156human leukocyte differentiation antigen, Cell surface antigen MS2, EC 3.4.24, EC 3.4.24.-, MGC134985, MS2, MS2disintegrin and metalloproteinase domain-containing protein 8

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage