Mouse PD-1 Antibody | R&D Systems AF1021 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse PD-1 Antibody

catalog :

AF1021

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 19

Reference
Corria Osorio J, Carmona S, Stefanidis E, Andreatta M, Ortiz Miranda Y, Muller T, et al. Orthogonal cytokine engineering enables novel synthetic effector states escaping canonical exhaustion in tumor-rejecting CD8+ T cells. Nat Immunol. 2023;24:869-883 pubmed publisher
Kaya T, Mattugini N, Liu L, Ji H, Cantuti Castelvetri L, Wu J, et al. CD8+ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging. Nat Neurosci. 2022;25:1446-1457 pubmed publisher
Codarri Deak L, Nicolini V, Hashimoto M, Karagianni M, Schwalie P, Lauener L, et al. PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells. Nature. 2022;610:161-172 pubmed publisher
Martins C, Silva M, Rasbach E, Singh P, Itoh Y, Williams J, et al. Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells. Sci Rep. 2022;12:12491 pubmed publisher
Lee G, Jun Y, Jeon Y, Lee D, Lee S, Kim J. Mice transgenic for human CTLA4-CD28 fusion gene show proliferation and transformation of ATLL-like and AITL-like T cells. Oncoimmunology. 2022;11:2015170 pubmed publisher
Wu G, Murugesan G, Nagala M, McCraw A, Haslam S, Dell A, et al. Activation of regulatory T cells triggers specific changes in glycosylation associated with Siglec-1-dependent inflammatory responses. Wellcome Open Res. 2021;6:134 pubmed publisher
Tirado Gonzalez I, Descot A, Soetopo D, Nevmerzhitskaya A, Schaffer A, Kur I, et al. AXL Inhibition in Macrophages Stimulates Host-versus-Leukemia Immunity and Eradicates Naïve and Treatment-Resistant Leukemia. Cancer Discov. 2021;11:2924-2943 pubmed publisher
Dudek M, Pfister D, Donakonda S, Filpe P, Schneider A, Laschinger M, et al. Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH. Nature. 2021;592:444-449 pubmed publisher
Tan Z, Chiu M, Yan C, Man K, Chen Z. Eliminating mesothelioma by AAV-vectored, PD1-based vaccination in the tumor microenvironment. Mol Ther Oncolytics. 2021;20:373-386 pubmed publisher
Crute B, Sheraden R, Ott V, Harley I, Getahun A, Cambier J. Inhibitory Receptor Trap: A Platform for Discovery of Inhibitory Receptors That Utilize Inositol Lipid and Phosphotyrosine Phosphatase Effectors. Front Immunol. 2020;11:592329 pubmed publisher
Liu B, Cao Q, Zhao X, Liu H, Zhang Y. Inhibition of TRPV1 by SHP-1 in nociceptive primary sensory neurons is critical in PD-L1 analgesia. JCI Insight. 2020;5: pubmed publisher
Lee G, Jun Y, Yoo H, Jeon Y, Lee D, Lee S, et al. Angioimmunoblastic T-cell lymphoma-like lymphadenopathy in mice transgenic for human RHOA with p.Gly17Val mutation. Oncoimmunology. 2020;9:1746553 pubmed publisher
Lerbs T, Cui L, King M, Chai T, Muscat C, Chung L, et al. CD47 prevents the elimination of diseased fibroblasts in scleroderma. JCI Insight. 2020;5: pubmed publisher
Hoefflin R, Harlander S, Schäfer S, Metzger P, Kuo F, Schönenberger D, et al. HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice. Nat Commun. 2020;11:4111 pubmed publisher
Rao G, Latha K, Ott M, Sabbagh A, Marisetty A, Ling X, et al. Anti-PD-1 Induces M1 Polarization in the Glioma Microenvironment and Exerts Therapeutic Efficacy in the Absence of CD8 Cytotoxic T Cells. Clin Cancer Res. 2020;26:4699-4712 pubmed publisher
Liu Y, Yang Z, Lai P, Huang Z, Sun X, Zhou T, et al. Bcl-6-directed follicular helper T cells promote vascular inflammatory injury in diabetic retinopathy. Theranostics. 2020;10:4250-4264 pubmed publisher
Ritzmann F, Jungnickel C, Vella G, Kamyschnikow A, Herr C, Li D, et al. IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer. Sci Rep. 2019;9:10353 pubmed publisher
Lee W, Lee Y, Choi M, Yun K, Won C, Lee M, et al. Expression of lymphocyte-activating gene 3 and T-cell immunoreceptor with immunoglobulin and ITIM domains in cutaneous melanoma and their correlation with programmed cell death 1 expression in tumor-infiltrating lymphocytes. J Am Acad Dermatol. 2019;81:219-227 pubmed publisher
Ruscher R, Kummer R, Lee Y, Jameson S, Hogquist K. CD8αα intraepithelial lymphocytes arise from two main thymic precursors. Nat Immunol. 2017;18:771-779 pubmed publisher

product information

master code :

AF1021

SKU :

AF1021

product name :

Mouse PD-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse PD-1 Antibody from R&D Systems is a goat polyclonal antibody to PD-1. This antibody reacts with human,mouse,transgenic mouse,xenograft. The Mouse PD-1 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,ELISA Capture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Flow Cytometry,CyTOF-ready.

target :

PD-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse PD-1, Leu25-Gln167, Accession # Q02242

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Xenograft

specificity :

Detects mouse PD-1 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human PD-1 is observed.

gene symbol :

PDCD1

top caption :

Detection of Mouse PD-1 antibody by Western Blot.

accessionNumbers :

Q02242

applications :

Immunohistochemistry,Western Blot,ELISA Capture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Flow Cytometry,CyTOF-ready

USD :

509 USD

alt names :

CD279, CD279 antigen, hPD-1, PD1, PD1hPD-l, PDCD1, programmed cell death 1, programmed cell death protein 1, Protein PD-1, SLEB2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage