Human/Mouse/Rat Phospho-ERK1(T202/Y204)/ERK2 (T185/Y187) Antibody

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Rat Phospho-ERK1(T202/Y204)/ERK2 (T185/Y187) Antibody

catalog :

AF1018

quantity :

100 ug (also 25 ug)

price :

399 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 25

Reference
Zhang J, Lu Y, Jia M, Bai Y, Sun L, Dong Z, et al. Kappa opioid receptor in nucleus accumbens regulates depressive-like behaviors following prolonged morphine withdrawal in mice. iScience. 2023;26:107536 pubmed publisher
Xia Q, Mao M, Zhan G, Luo Z, Zhao Y, Li X. SENP3-mediated deSUMOylation of c-Jun facilitates microglia-induced neuroinflammation after cerebral ischemia and reperfusion injury. iScience. 2023;26:106953 pubmed publisher
Stulpinas A, Sereika M, Vitkeviciene A, Imbrasaite A, Krestnikova N, Kalvelyte A. Crosstalk between protein kinases AKT and ERK1/2 in human lung tumor-derived cell models. Front Oncol. 2022;12:1045521 pubmed publisher
Okada M, Fukuyama K, Motomura E. Dose-Dependent Biphasic Action of Quetiapine on AMPK Signalling via 5-HT7 Receptor: Exploring Pathophysiology of Clinical and Adverse Effects of Quetiapine. Int J Mol Sci. 2022;23: pubmed publisher
Ishigamori R, Naruse M, Hirata A, Maru Y, Hippo Y, Imai T. The potential of organoids in toxicologic pathology: Histopathological and immunohistochemical evaluation of a mouse normal tissue-derived organoid-based carcinogenesis model. J Toxicol Pathol. 2022;35:211-223 pubmed publisher
Fukuyama K, Motomura E, Okada M. Brexpiprazole Reduces 5-HT7 Receptor Function on Astroglial Transmission Systems. Int J Mol Sci. 2022;23: pubmed publisher
Chang H, Sun J, Cheng C, Liang Y, Chen Y. High Mobility Group A 1 Expression as a Poor Prognostic Marker Associated with Tumor Invasiveness in Gastric Cancer. Life (Basel). 2022;12: pubmed publisher
Shiroyama T, Fukuyama K, Okada M. Distinct Effects of Escitalopram and Vortioxetine on Astroglial L-Glutamate Release Associated with Connexin43. Int J Mol Sci. 2021;22: pubmed publisher
Machida Y, Imai T. Different properties of mammary carcinogenesis induced by two chemical carcinogens, DMBA and PhIP, in heterozygous BALB/c Trp53 knockout mice. Oncol Lett. 2021;22:738 pubmed publisher
Massman L, Pereckas M, Zwagerman N, Olivier Van Stichelen S. O-GlcNAcylation Is Essential for Rapid Pomc Expression and Cell Proliferation in Corticotropic Tumor Cells. Endocrinology. 2021;162: pubmed publisher
Liu S, An G, Cao Q, Li T, Jia X, Lei L. The miR-106b/NR2F2-AS1/PLEKHO2 Axis Regulates Migration and Invasion of Colorectal Cancer through the MAPK Pathway. Int J Mol Sci. 2021;22: pubmed publisher
Soleimanpour E, Bergado Acosta J, Landgraf P, Mayer D, Dankert E, Dieterich D, et al. Regulation of CREB Phosphorylation in Nucleus Accumbens after Relief Conditioning. Cells. 2021;10: pubmed publisher
Rao L, Wang Y, Zhang L, Wu G, Zhang L, Wang F, et al. IL-24 deficiency protects mice against bleomycin-induced pulmonary fibrosis by repressing IL-4-induced M2 program in macrophages. Cell Death Differ. 2021;28:1270-1283 pubmed publisher
Fukuyama K, Okada M. Age-Dependent and Sleep/Seizure-Induced Pathomechanisms of Autosomal Dominant Sleep-Related Hypermotor Epilepsy. Int J Mol Sci. 2020;21: pubmed publisher
Liu J, Liu J, Bai M, Wang H. Protective effect of puerarin against burn-induced heart injury in rats. Exp Ther Med. 2020;20:275-282 pubmed publisher
S xe1 nchez A, Garc xed a Acero M, Paredes A, Quero R, Ortega R, Rojas J, et al. Immunodeficiency in a Patient with 22q11.2 Distal Deletion Syndrome and a p.Ala7dup Variant in the MAPK1 Gene. Mol Syndromol. 2020;11:15-23 pubmed publisher
Niersmann C, Röhrig K, Bluher M, Roden M, Herder C, Carstensen Kirberg M. Increased Release of Proinflammatory Proteins in Primary Human Adipocytes and Activation of the Inflammatory NFĸB, p38, and ERK Pathways upon Omentin Treatment. Obes Facts. 2020;13:221-236 pubmed publisher
Burgueño J, Lang J, Santander A, Fernandez I, Fernandez E, Zaias J, et al. Fluid supplementation accelerates epithelial repair during chemical colitis. PLoS ONE. 2019;14:e0215387 pubmed publisher
Herbrich S, Kannan S, Nolo R, Hornbaker M, Chandra J, Zweidler McKay P. Characterization of TRKA signaling in acute myeloid leukemia. Oncotarget. 2018;9:30092-30105 pubmed publisher
Wan Z, Xu C, Chen X, Xie H, Li Z, Wang J, et al. PI(4,5)P2 determines the threshold of mechanical force-induced B cell activation. J Cell Biol. 2018;217:2565-2582 pubmed publisher
Scheers N, Pereira D, Faria N, Powell J. Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells. Oncotarget. 2018;9:17066-17077 pubmed publisher
Wilson K, Jagger A, Walker M, Seinkmane E, Fox J, Kröger R, et al. Glycans modify mesenchymal stem cell differentiation to impact on the function of resulting osteoblasts. J Cell Sci. 2018;131: pubmed publisher
Rodrigues B, Muñoz V, Kuga G, Gaspar R, Nakandakari S, Crisol B, et al. Obesity Increases Mitogen-Activated Protein Kinase Phosphatase-3 Levels in the Hypothalamus of Mice. Front Cell Neurosci. 2017;11:313 pubmed publisher
Montoya A, Amaya C, Belmont A, Diab N, Trevino R, Villanueva G, et al. Use of non-selective β-blockers is associated with decreased tumor proliferative indices in early stage breast cancer. Oncotarget. 2017;8:6446-6460 pubmed publisher
Li Y, Choi D, Lee E, Seo S, Lee S, Cho E. Sirtuin 3 (SIRT3) Regulates Î±-Smooth Muscle Actin (Î±-SMA) Production through the Succinate Dehydrogenase-G Protein-coupled Receptor 91 (GPR91) Pathway in Hepatic Stellate Cells. J Biol Chem. 2016;291:10277-92 pubmed publisher

product information

brand :

R&D Systems

master code :

AF1018

SKU :

AF1018

product name :

Human/Mouse/Rat Phospho-ERK1(T202/Y204)/ERK2 (T185/Y187) Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse/Rat Phospho-ERK1(T202/Y204)/ERK2 (T185/Y187) Antibody from R&D Systems is a rabbit polyclonal antibody to ERK1/ERK2. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat Phospho-ERK1(T202/Y204)/ERK2 (T185/Y187) Antibody has been validated for the following applications: Multiplex Immunofluorescence,Western Blot,Simple Western,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Flow Cytometry,CyTOF-ready.

target :

ERK1/ERK2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.1 ug/mL, Simple Western 5 ug/mL, Flow Cytometry 2.5 ug/10^6 cells, Immunohistochemistry 5-15 ug/mL, CyTOF-ready

host :

Rabbit

immunogen :

Phosphopeptide containing ERK1 T202/Y204 sites

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat

specificity :

Detects human, mouse and rat Phospho-ERK1/ERK2 when dually phosphorylated at T202/Y204 and T185/Y187, respectively.

top caption :

Detection of Human Phospho-ERK1 (T202/Y204) and ERK2 (T185/Y187) antibody by Western Blot.

applications :

Flow Cytometry,CyTOF-ready,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Simple Western,Immunocytochemistry

USD :

399 USD

alt names :

ERK1, ERK-1, ERT1, ERT2, Extracellular signal-regulated kinase 1, extracellular signal-related kinase 1, HS44KDAP, HUMKER1A, Insulin-stimulated MAP2 kinase, MAPK 1, MAPK1, MAPK2, MAPK3, Microtubule-associated protein 2 kinase, mitogen-activated protein kinase 3, p41mapk, p42mapk, p44erk1, p44-ERK1, p44mapk, p44-MAPK, PRKM1, PRKM2, PRKM3

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage