product summary
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company name :
R&D Systems
product type :
antibody
product name :
Rat UNC5H2/UNC5B Antibody
catalog :
AF1006
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 5
Reference
Xiao W, Pinilla Baquero A, Faulkner J, Song X, Prabhakar P, Qiu H, et al. Robo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis. Sci Rep. 2022;12:4352 pubmed publisher
Boyé K, Geraldo L, Furtado J, Pibouin Fragner L, Poulet M, Kim D, et al. Endothelial Unc5B controls blood-brain barrier integrity. Nat Commun. 2022;13:1169 pubmed publisher
Ta xef b S, Lamand xe9 N, Martin S, Coulpier F, Topilko P, Brunet I. Myelinating Schwann cells and Netrin-1 control intra-nervous vascularization of the developing mouse sciatic nerve. elife. 2022;11: pubmed publisher
Hadi T, Boytard L, Silvestro M, Alebrahim D, Jacob S, Feinstein J, et al. Macrophage-derived netrin-1 promotes abdominal aortic aneurysm formation by activating MMP3 in vascular smooth muscle cells. Nat Commun. 2018;9:5022 pubmed publisher
Yamahara K, Nakagawa T, Ito J, Kinoshita K, Omori K, Yamamoto N. Netrin 1 mediates protective effects exerted by insulin-like growth factor 1 on cochlear hair cells. Neuropharmacology. 2017;119:26-39 pubmed publisher
product information
master code :
AF1006
SKU :
AF1006
product name :
Rat UNC5H2/UNC5B Antibody
unit size :
100 ug (also 25 ug)
description :
The Rat UNC5H2/UNC5B Antibody from R&D Systems is a goat polyclonal antibody to UNC5H2/UNC5B. This antibody reacts with human,mouse,rat. The Rat UNC5H2/UNC5B Antibody has been validated for the following applications: Neutralization,Cell Migration,Immunoprecipitation,Western Blot,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Immunohistochemistry.
target :
UNC5H2/UNC5B
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant rat UNC5H2, Gly27-Asp373, Accession # O08722
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects rat UNC5H2 in direct ELISAs and Western blots.
gene symbol :
UNC5B
top caption :
Detection of Rat UNC5H2 antibody by Western Blot.
accessionNumbers :
O08722
applications :
Neutralization,Cell Migration,Immunoprecipitation,Western Blot,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,Immunohistochemistry
USD :
489 USD
alt names :
p53RDL1, p53-regulated receptor for death and life protein 1, Protein unc-5 homolog 2, Protein unc-5 homolog B, transmembrane receptor Unc5H2, unc5 (C.elegans homolog) b, unc-5 homolog 2, unc-5 homolog B (C. elegans), UNC5B, UNC5H2netrin receptor UNC5B
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.