product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse VE-Cadherin Antibody
catalog :
AF1002
quantity :
100 ug (also 25 ug)
price :
549 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 100
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 5b
Maderna C, Pisati F, Tripodo C, Dejana E, Malinverno M. A murine model of cerebral cavernous malformations with acute hemorrhage. iScience. 2022;25:103943 pubmed publisher
  • immunocytochemistry; human; fig 1c
Sáinz Jaspeado M, Smith R, Plunde O, Pawelzik S, Jin Y, Nordling S, et al. Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium. Circulation. 2021;144:1629-1645 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 3e
Qin Z, Liu F, Blair R, Wang C, Yang H, Mudd J, et al. Endothelial cell infection and dysfunction, immune activation in severe COVID-19. Theranostics. 2021;11:8076-8091 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig s4a, s5a
An X, Ogawa Wong A, Carmody C, Ambrosio R, Cicatiello A, Luongo C, et al. A Type 2 Deiodinase-Dependent Increase in Vegfa Mediates Myoblast-Endothelial Cell Crosstalk During Skeletal Muscle Regeneration. Thyroid. 2021;31:115-127 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:300; loading ...; fig 1a
Engelbrecht E, Lévesque M, He L, Vanlandewijck M, Nitzsche A, Niazi H, et al. Sphingosine 1-phosphate-regulated transcriptomes in heterogenous arterial and lymphatic endothelium of the aorta. elife. 2020;9: pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 3b
Yanagida K, Liu C, Faraco G, Galvani S, Smith H, Burg N, et al. Size-selective opening of the blood-brain barrier by targeting endothelial sphingosine 1-phosphate receptor 1. Proc Natl Acad Sci U S A. 2017;114:4531-4536 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig s3d
Tian L, Goldstein A, Wang H, Ching Lo H, Sun Kim I, Welte T, et al. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming. Nature. 2017;544:250-254 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3
  • immunocytochemistry; mouse; loading ...; fig 3c
Kasaai B, Caolo V, Peacock H, Lehoux S, Gomez Perdiguero E, Luttun A, et al. Erythro-myeloid progenitors can differentiate from endothelial cells and modulate embryonic vascular remodeling. Sci Rep. 2017;7:43817 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig s2a
Pu W, Zhang H, Huang X, Tian X, He L, Wang Y, et al. Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration. Nat Commun. 2016;7:13369 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; fig 5
Chen Q, Zhang H, Liu Y, Adams S, Eilken H, Stehling M, et al. Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells. Nat Commun. 2016;7:12422 pubmed publisher
  • immunohistochemistry; mouse; 1:200; fig s1
Liu Q, Yang R, Huang X, Zhang H, He L, Zhang L, et al. Genetic lineage tracing identifies in situ Kit-expressing cardiomyocytes. Cell Res. 2016;26:119-30 pubmed publisher
Xue L, Zhao G, Gong N, Han X, Shepherd S, Xiong X, et al. Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery. Nat Nanotechnol. 2025;20:132-143 pubmed publisher
Park H, Song J, Jeong H, Gr xf6 nloh M, Koh B, Bovay E, et al. Apelin modulates inflammation and leukocyte recruitment in experimental autoimmune encephalomyelitis. Nat Commun. 2024;15:6282 pubmed publisher
Halder S, Sapkota A, Milner R. β1 integrins play a critical role maintaining vascular integrity in the hypoxic spinal cord, particularly in white matter. Acta Neuropathol Commun. 2024;12:45 pubmed publisher
Chen D, Wiggins D, Sevick E, Davis M, King P. An EPHB4-RASA1 signaling complex inhibits shear stress-induced Ras-MAPK activation in lymphatic endothelial cells to promote the development of lymphatic vessel valves. bioRxiv. 2023;: pubmed publisher
Kizhatil K, Clark G, Sunderland D, Bhandari A, Horbal L, Balasubramanian R, et al. FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-cadherin. bioRxiv. 2023;: pubmed publisher
Kaneko K, Liang Y, Liu Q, Zhang S, Scheiter A, Song D, et al. Identification of CD133+ intercellsomes in intercellular communication to offset intracellular signal deficit. elife. 2023;12: pubmed publisher
He S, Guo Z, Zhou M, Wang H, Zhang Z, Shi M, et al. Spatial-temporal proliferation of hepatocytes during pregnancy revealed by genetic lineage tracing. Cell Stem Cell. 2023;30:1549-1558.e5 pubmed publisher
Chovatiya G, Li K, Li J, Ghuwalewala S, Tumbar T. Alk1 acts in non-endothelial VE-cadherin+ perineurial cells to maintain nerve branching during hair homeostasis. Nat Commun. 2023;14:5623 pubmed publisher
Thatcher K, Mattern C, Chaparro D, Goveas V, McDermott M, Fulton J, et al. Temporal Progression of Aortic Valve Pathogenesis in a Mouse Model of Osteogenesis Imperfecta. J Cardiovasc Dev Dis. 2023;10: pubmed publisher
Zhang T, Xu D, Liu J, Wang M, Duan L, Liu M, et al. Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation. Nat Cell Biol. 2023;25:950-962 pubmed publisher
Cornuault L, H xe9 rion F, Bourguignon C, Rouault P, Foussard N, Alzieu P, et al. Partial Mural Cell Ablation Disrupts Coronary Vasculature Integrity and Induces Systolic Dysfunction. J Am Heart Assoc. 2023;12:e029279 pubmed publisher
Park M, Lee H, Jang H, Kim N, Lee J, Jeong Y, et al. Cytarabine induces cachexia with lipid malabsorption via zippering the junctions of lacteal in murine small intestine. J Lipid Res. 2023;64:100387 pubmed publisher
Hao X, Shen Y, Chen N, Zhang W, Valverde E, Wu L, et al. Osteoprogenitor-GMP crosstalk underpins solid tumor-induced systemic immunosuppression and persists after tumor removal. Cell Stem Cell. 2023;30:648-664.e8 pubmed publisher
Wang R, Ni C, Lou X, Zhang L, Wang L, Yao X, et al. IFNγ blockade in capillary leak site improves tumour chemotherapy by inhibiting lactate-induced endocytosis of vascular endothelial-cadherins. Int J Biol Sci. 2023;19:1490-1508 pubmed publisher
Jiang H, Bai L, Song S, Yin Q, Shi A, Zhou B, et al. EZH2 controls epicardial cell migration during heart development. Life Sci Alliance. 2023;6: pubmed publisher
Liu H, Duan R, He X, Qi J, Xing T, Wu Y, et al. Endothelial deletion of PTBP1 disrupts ventricular chamber development. Nat Commun. 2023;14:1796 pubmed publisher
Niaudet C, Jung B, Kuo A, Swendeman S, Bull E, Seno T, et al. Therapeutic activation of endothelial sphingosine-1-phosphate receptor 1 by chaperone-bound S1P suppresses proliferative retinal neovascularization. EMBO Mol Med. 2023;15:e16645 pubmed publisher
Lee E, Lee E, Kong E, Chon H, Llaiqui Condori M, Park C, et al. An agonistic anti-Tie2 antibody suppresses the normal-to-tumor vascular transition in the glioblastoma invasion zone. Exp Mol Med. 2023;55:470-484 pubmed publisher
Shirakura K, Baluk P, Nottebaum A, Ipe U, Peters K, McDonald D, et al. Shear stress control of vascular leaks and atheromas through Tie2 activation by VE-PTP sequestration. EMBO Mol Med. 2023;15:e16128 pubmed publisher
Kazenwadel J, Venugopal P, Oszmiana A, Toubia J, Arriola Martinez L, Panara V, et al. A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature. Nature. 2023;614:343-348 pubmed publisher
Paul M, Chakraborty S, Islam S, Ain R. Trans-differentiation of trophoblast stem cells: implications in placental biology. Life Sci Alliance. 2023;6: pubmed publisher
Zhang W, Xu Z, Hao X, He T, Li J, Shen Y, et al. Bone Metastasis Initiation Is Coupled with Bone Remodeling through Osteogenic Differentiation of NG2+ Cells. Cancer Discov. 2023;13:474-495 pubmed publisher
Long Y, Chen H, Deng J, Ning J, Yang P, Qiao L, et al. Deficiency of endothelial FGFR1 alleviates hyperoxia-induced bronchopulmonary dysplasia in neonatal mice. Front Pharmacol. 2022;13:1039103 pubmed publisher
Baganha F, Sluiter T, de Jong R, van Alst L, Peters H, Jukema J, et al. Phosphorylcholine Monoclonal Antibody Therapy Decreases Intraplaque Angiogenesis and Intraplaque Hemorrhage in Murine Vein Grafts. Int J Mol Sci. 2022;23: pubmed publisher
Zhao B, Ni Y, Zhang H, Zhao Y, Li L. Endothelial deletion of TBK1 contributes to BRB dysfunction via CXCR4 phosphorylation suppression. Cell Death Discov. 2022;8:429 pubmed publisher
Corti F, Ristori E, Rivera Molina F, Toomre D, Zhang J, Mihailovic J, et al. Syndecan-2 selectively regulates VEGF-induced vascular permeability. Nat Cardiovasc Res. 2022;1:518-528 pubmed publisher
Maeso Alonso L, Alonso Olivares H, Mart xed nez Garc xed a N, L xf3 pez Ferreras L, Villoch Fern xe1 ndez J, Puente Santamar xed a L, et al. p73 is required for vessel integrity controlling endothelial junctional dynamics through Angiomotin. Cell Mol Life Sci. 2022;79:535 pubmed publisher
Hashimoto R, Takahashi J, Shirakura K, Funatsu R, Kosugi K, Deguchi S, et al. SARS-CoV-2 disrupts respiratory vascular barriers by suppressing Claudin-5 expression. Sci Adv. 2022;8:eabo6783 pubmed publisher
Hong M, Wu Y, Zhang H, Gu J, Chen J, Guan Y, et al. Network pharmacology and experimental analysis to reveal the mechanism of Dan-Shen-Yin against endothelial to mesenchymal transition in atherosclerosis. Front Pharmacol. 2022;13:946193 pubmed publisher
Belcher J, Nguyen J, Chen C, Abdulla F, Conglin R, Ivy Z, et al. MASP-2 and MASP-3 inhibitors block complement activation, inflammation, and microvascular stasis in a murine model of vaso-occlusion in sickle cell disease. Transl Res. 2022;249:1-12 pubmed publisher
Moulis M, Runser S, Glorieux L, Dauguet N, Vanderaa C, Gatto L, et al. Identification and implication of tissue-enriched ligands in epithelial-endothelial crosstalk during pancreas development. Sci Rep. 2022;12:12498 pubmed publisher
Richards M, Nwadozi E, Pal S, Martinsson P, Kaakinen M, Gloger M, et al. Claudin5 protects the peripheral endothelial barrier in an organ and vessel-type-specific manner. elife. 2022;11: pubmed publisher
Kataru R, Park H, Shin J, Baik J, Sarker A, Brown S, et al. Structural and Functional Changes in Aged Skin Lymphatic Vessels. Front Aging. 2022;3:864860 pubmed publisher
Tisch N, Mogler C, Stojanovic A, Luck R, Korhonen E, Ellerkmann A, et al. Caspase-8 in endothelial cells maintains gut homeostasis and prevents small bowel inflammation in mice. EMBO Mol Med. 2022;14:e14121 pubmed publisher
Tarafdar A, Wolska N, Krisp C, Schluter H, Pula G. The amyloid peptide β disrupts intercellular junctions and increases endothelial permeability in a NADPH oxidase 1-dependent manner. Redox Biol. 2022;52:102287 pubmed publisher
Hadland B, Varnum Finney B, Dozono S, Dignum T, Nourigat Mckay C, Heck A, et al. Engineering a niche supporting hematopoietic stem cell development using integrated single-cell transcriptomics. Nat Commun. 2022;13:1584 pubmed publisher
Duong C, Brückner R, Schmitt M, Nottebaum A, Braun L, Meyer Zu Brickwedde M, et al. Force-induced changes of α-catenin conformation stabilize vascular junctions independently of vinculin. J Cell Sci. 2021;134: pubmed publisher
Arpino J, Yin H, Prescott E, Staples S, Nong Z, Li F, et al. Low-flow intussusception and metastable VEGFR2 signaling launch angiogenesis in ischemic muscle. Sci Adv. 2021;7:eabg9509 pubmed publisher
Heino S, Fang S, Lähde M, Högström J, Nassiri S, Campbell A, et al. Lef1 restricts ectopic crypt formation and tumor cell growth in intestinal adenomas. Sci Adv. 2021;7:eabj0512 pubmed publisher
Koch P, Sandorski K, Heil J, Schmid C, K xfc rschner S, Hoffmann J, et al. Imbalanced Activation of Wnt-/β-Catenin-Signaling in Liver Endothelium Alters Normal Sinusoidal Differentiation. Front Physiol. 2021;12:722394 pubmed publisher
Nordquist E, Dutta P, Kodigepalli K, Mattern C, McDermott M, Trask A, et al. Tgfβ1-Cthrc1 Signaling Plays an Important Role in the Short-Term Reparative Response to Heart Valve Endothelial Injury. Arterioscler Thromb Vasc Biol. 2021;41:2923-2942 pubmed publisher
Mesnieres M, Böhm A, Peredo N, Trompet D, Valle Tenney R, Bajaj M, et al. Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches. Cell Rep. 2021;36:109618 pubmed publisher
Kataru R, Baik J, Park H, Ly C, Shin J, Schwartz N, et al. Lymphatic-specific intracellular modulation of receptor tyrosine kinase signaling improves lymphatic growth and function. Sci Signal. 2021;14: pubmed publisher
Chen Q, Zhou X, Hou R, Zhou Z, Wang Z, Chen Y, et al. Aminophylline modulates the permeability of endothelial cells via the Slit2-Robo4 pathway in lipopolysaccharide-induced inflammation. Exp Ther Med. 2021;22:1042 pubmed publisher
Selbonne S, Madjene C, Salmon B, Boulaftali Y, Bouton M, Arocas V. Protease nexin-1 deficiency increases mouse hindlimb neovascularisation following ischemia and accelerates femoral artery perfusion. Sci Rep. 2021;11:13412 pubmed publisher
Richards M, Pal S, Sjöberg E, Martinsson P, Venkatraman L, Claesson Welsh L. Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin α5. Cell Rep. 2021;35:109268 pubmed publisher
Ninchoji T, Love D, Smith R, Hedlund M, Vestweber D, Sessa W, et al. eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin. elife. 2021;10: pubmed publisher
Zhang W, Bado I, Hu J, Wan Y, Wu L, Wang H, et al. The bone microenvironment invigorates metastatic seeds for further dissemination. Cell. 2021;184:2471-2486.e20 pubmed publisher
Baganha F, de Jong R, Peters E, Voorham W, Jukema J, Delibegovic M, et al. Atorvastatin pleiotropically decreases intraplaque angiogenesis and intraplaque haemorrhage by inhibiting ANGPT2 release and VE-Cadherin internalization. Angiogenesis. 2021;24:567-581 pubmed publisher
Russo E, Runge P, Jahromi N, Naboth H, Landtwing A, Montecchi R, et al. CD112 Regulates Angiogenesis and T Cell Entry into the Spleen. Cells. 2021;10: pubmed publisher
Nitzsche A, Pietilä R, Love D, Testini C, Ninchoji T, Smith R, et al. Paladin is a phosphoinositide phosphatase regulating endosomal VEGFR2 signalling and angiogenesis. EMBO Rep. 2021;22:e50218 pubmed publisher
Zhao G, Weiner A, Neupauer K, De Mello Costa M, Palashikar G, Adams Tzivelekidis S, et al. Regeneration of the pulmonary vascular endothelium after viral pneumonia requires COUP-TF2. Sci Adv. 2020;6: pubmed publisher
Hollier P, Chapouly C, Diop A, Guimbal S, Cornuault L, Gadeau A, et al. Full-length Dhh and N-terminal Shh act as competitive antagonists to regulate angiogenesis and vascular permeability. Cardiovasc Res. 2021;117:2489-2501 pubmed publisher
Chapouly C, Hollier P, Guimbal S, Cornuault L, Gadeau A, Renault M. Desert Hedgehog-Driven Endothelium Integrity Is Enhanced by Gas1 (Growth Arrest-Specific 1) but Negatively Regulated by Cdon (Cell Adhesion Molecule-Related/Downregulated by Oncogenes). Arterioscler Thromb Vasc Biol. 2020;40:e336-e349 pubmed publisher
Propson N, Roy E, Litvinchuk A, Köhl J, Zheng H. Endothelial C3a receptor mediates vascular inflammation and blood-brain barrier permeability during aging. J Clin Invest. 2021;131: pubmed publisher
Jeong S, Cho M, Ko N, Kim S, Jung I, Min J, et al. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm. Exp Mol Med. 2020;52:1587-1601 pubmed publisher
Tabibian A, Ghaffari S, Vargas D, Van Oosterwyck H, Jones E. Simulating flow induced migration in vascular remodelling. PLoS Comput Biol. 2020;16:e1007874 pubmed publisher
Hong S, Yang M, Cho H, Park I, Bae H, Choe K, et al. Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi. Nat Commun. 2020;11:4102 pubmed publisher
Lee B, Shin H, Oh J, Park J, Park M, Yang S, et al. An autophagic deficit in the uterine vessel microenvironment provokes hyperpermeability through deregulated VEGFA, NOS1, and CTNNB1. Autophagy. 2021;17:1649-1666 pubmed publisher
Norden P, Sabine A, Wang Y, Demir C, Liu T, Petrova T, et al. Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation. elife. 2020;9: pubmed publisher
Krambs J, Abou Ezzi G, Yao J, Link D. Canonical signaling by TGF family members in mesenchymal stromal cells is dispensable for hematopoietic niche maintenance under basal and stress conditions. PLoS ONE. 2020;15:e0233751 pubmed publisher
Wang Z, Wang F, Zhong J, Zhu T, Zheng Y, Zhao T, et al. Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors. Nat Commun. 2020;11:2163 pubmed publisher
Betterman K, Sutton D, Secker G, Kazenwadel J, Oszmiana A, Lim L, et al. Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow. J Clin Invest. 2020;130:3315-3328 pubmed publisher
Schimmel L, Fukuhara D, Richards M, Jin Y, Essebier P, Frampton E, et al. c-Src controls stability of sprouting blood vessels in the developing retina independently of cell-cell adhesion through focal adhesion assembly. Development. 2020;147: pubmed publisher
Yanagida K, Engelbrecht E, Niaudet C, Jung B, Gaengel K, Holton K, et al. Sphingosine 1-Phosphate Receptor Signaling Establishes AP-1 Gradients to Allow for Retinal Endothelial Cell Specialization. Dev Cell. 2020;52:779-793.e7 pubmed publisher
Darling T, Mimche P, Bray C, Umaru B, Brady L, Stone C, et al. EphA2 contributes to disruption of the blood-brain barrier in cerebral malaria. PLoS Pathog. 2020;16:e1008261 pubmed publisher
Pu W, Han X, He L, Li Y, Huang X, Zhang M, et al. A genetic system for tissue-specific inhibition of cell proliferation. Development. 2020;147: pubmed publisher
Wu J, Li Y, Chen A, Hong C, Zhang C, Wang H, et al. Inhibition of Sema4D/PlexinB1 signaling alleviates vascular dysfunction in diabetic retinopathy. EMBO Mol Med. 2020;12:e10154 pubmed publisher
Luck R, Urban S, Karakatsani A, Harde E, Sambandan S, Nicholson L, et al. VEGF/VEGFR2 signaling regulates hippocampal axon branching during development. elife. 2019;8: pubmed publisher
Duong C, Nottebaum A, Butz S, Volkery S, Zeuschner D, Stehling M, et al. Interference With ESAM (Endothelial Cell-Selective Adhesion Molecule) Plus Vascular Endothelial-Cadherin Causes Immediate Lethality and Lung-Specific Blood Coagulation. Arterioscler Thromb Vasc Biol. 2020;40:378-393 pubmed publisher
Chiaverina G, di Blasio L, Monica V, Accardo M, Palmiero M, Peracino B, et al. Dynamic Interplay between Pericytes and Endothelial Cells during Sprouting Angiogenesis. Cells. 2019;8: pubmed publisher
Qu X, Violette K, Sewell Loftin M, Soslow J, Saint Jean L, Hinton R, et al. Loss of flow responsive Tie1 results in Impaired
Aortic valve remodeling. Dev Biol. 2019;455:73-84 pubmed publisher
Zhang J, Supakorndej T, Krambs J, Rao M, Abou Ezzi G, Ye R, et al. Bone marrow dendritic cells regulate hematopoietic stem/progenitor cell trafficking. J Clin Invest. 2019;129:2920-2931 pubmed publisher
Han X, Wang Y, Pu W, Huang X, Qiu L, Li Y, et al. Lineage Tracing Reveals the Bipotency of SOX9+ Hepatocytes during Liver Regeneration. Stem Cell Reports. 2019;12:624-638 pubmed publisher
Eelen G, Dubois C, Cantelmo A, Goveia J, Bruning U, DeRan M, et al. Role of glutamine synthetase in angiogenesis beyond glutamine synthesis. Nature. 2018;561:63-69 pubmed publisher
Niland S, Komljenovic D, Macas J, Bracht T, Bauerle T, Liebner S, et al. Rhodocetin-αβ selectively breaks the endothelial barrier of the tumor vasculature in HT1080 fibrosarcoma and A431 epidermoid carcinoma tumor models. Oncotarget. 2018;9:22406-22422 pubmed publisher
Blecharz Lang K, Prinz V, Burek M, Frey D, Schenkel T, Krug S, et al. Gelatinolytic activity of autocrine matrix metalloproteinase-9 leads to endothelial de-arrangement in Moyamoya disease. J Cereb Blood Flow Metab. 2018;38:1940-1953 pubmed publisher
Milo I, Blecher Gonen R, Barnett Itzhaki Z, Bar Ziv R, Tal O, Gurevich I, et al. The bone marrow is patrolled by NK cells that are primed and expand in response to systemic viral activation. Eur J Immunol. 2018;48:1137-1152 pubmed publisher
Guo L, Akahori H, Harari E, Smith S, Polavarapu R, Karmali V, et al. CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis. J Clin Invest. 2018;128:1106-1124 pubmed publisher
Cao J, Ehling M, März S, Seebach J, Tarbashevich K, Sixta T, et al. Polarized actin and VE-cadherin dynamics regulate junctional remodelling and cell migration during sprouting angiogenesis. Nat Commun. 2017;8:2210 pubmed publisher
Hu J, Dziumbla S, Lin J, Bibli S, Zukunft S, de Mos J, et al. Inhibition of soluble epoxide hydrolase prevents diabetic retinopathy. Nature. 2017;552:248-252 pubmed publisher
Tsang K, Hyun J, Cheng K, Vargas M, Mehta D, Ushio Fukai M, et al. Embryonic Stem Cell Differentiation to Functional Arterial Endothelial Cells through Sequential Activation of ETV2 and NOTCH1 Signaling by HIF1?. Stem Cell Reports. 2017;9:796-806 pubmed publisher
Luo M, Flood E, Almeida D, Yan L, Berlin D, Heerdt P, et al. Annexin A2 supports pulmonary microvascular integrity by linking vascular endothelial cadherin and protein tyrosine phosphatases. J Exp Med. 2017;214:2535-2545 pubmed publisher
Mead A, Neo W, Barkas N, Matsuoka S, Giustacchini A, Facchini R, et al. Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation. J Exp Med. 2017;214:2005-2021 pubmed publisher
Ding B, Liu C, Sun Y, Chen Y, Swendeman S, Jung B, et al. HDL activation of endothelial sphingosine-1-phosphate receptor-1 (S1P1) promotes regeneration and suppresses fibrosis in the liver. JCI Insight. 2016;1:e87058 pubmed publisher
Zhang J, Link D. Targeting of Mesenchymal Stromal Cells by Cre-Recombinase Transgenes Commonly Used to Target Osteoblast Lineage Cells. J Bone Miner Res. 2016;31:2001-2007 pubmed publisher
Shen Y, Cheng F, Sharma M, Merkulova Y, Raithatha S, Parkinson L, et al. Granzyme B Deficiency Protects against Angiotensin II-Induced Cardiac Fibrosis. Am J Pathol. 2016;186:87-100 pubmed publisher
Yin H, Frontini M, Arpino J, Nong Z, O Neil C, Xu Y, et al. Fibroblast Growth Factor 9 Imparts Hierarchy and Vasoreactivity to the Microcirculation of Renal Tumors and Suppresses Metastases. J Biol Chem. 2015;290:22127-42 pubmed publisher
Zang G, Gustafsson K, Jamalpour M, Hong J, Genové G, Welsh M. Vascular dysfunction and increased metastasis of B16F10 melanomas in Shb deficient mice as compared with their wild type counterparts. BMC Cancer. 2015;15:234 pubmed publisher
product information
master code :
AF1002
SKU :
AF1002
product name :
Mouse VE-Cadherin Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse VE-Cadherin Antibody from R&D Systems is a goat polyclonal antibody to VE-Cadherin. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse VE-Cadherin Antibody has been validated for the following applications: Immunohistochemistry,Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western,Dual RNAscope ISH-IHC Compatible.
target :
VE-Cadherin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse VE-Cadherin, Asp46-Gln592, Accession # 2208309A
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat,Transgenic Mouse
specificity :
Detects mouse VE-Cadherin in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant human VE-Cadherin is observed.
gene symbol :
CDH5
top caption :
Detection of Mouse VE-Cadherin antibody by Western Blot.
accessionNumbers :
2208309A
applications :
Immunocytochemistry,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Simple Western,Dual RNAscope ISH-IHC Compatible
USD :
549 USD
alt names :
7B4, 7B4 antigen, cadherin 5, type 2 (vascular endothelium), cadherin 5, type 2, VE-cadherin (vascular epithelium), cadherin-5, CD144, CD144 antigen, CDH5, endothelial-specific cadherin, FLJ17376, Vascular endothelial cadherin, VE-cadherin, VECadherin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.