Human/Mouse Caspase-3 Antibody | R&D Systems AF-605-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse Caspase-3 Antibody

catalog :

AF-605-NA

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 13

Reference
Peng Z, Gillissen B, Richter A, Sinnberg T, Schlaak M, Eberle J. Enhanced Apoptosis and Loss of Cell Viability in Melanoma Cells by Combined Inhibition of ERK and Mcl-1 Is Related to Loss of Mitochondrial Membrane Potential, Caspase Activation and Upregulation of Proapoptotic Bcl-2 Proteins. Int J Mol Sci. 2023;24: pubmed publisher
Kushalan S, D souza L, Aloysius K, Sharma A, Hegde S. Toxicity Assessment of Curculigo orchioides Leaf Extract Using Drosophila melanogaster: A Preliminary Study. Int J Environ Res Public Health. 2022;19: pubmed publisher
Virgana R, Atik N, Gunadi J, Jonathan E, Ramadhani D, Soetadji R, et al. MitoTEMPOL Inhibits ROS-Induced Retinal Vascularization Pattern by Modulating Autophagy and Apoptosis in Rat-Injected Streptozotocin Model. Life (Basel). 2022;12: pubmed publisher
Montinaro A, Areso Zubiaur I, Saggau J, Kretz A, Ferreira R, Hassan O, et al. Potent pro-apoptotic combination therapy is highly effective in a broad range of cancers. Cell Death Differ. 2022;29:492-503 pubmed publisher
McKenzie B, Fernandes J, Doan M, Schmitt L, Branton W, Power C. Activation of the executioner caspases-3 and -7 promotes microglial pyroptosis in models of multiple sclerosis. J Neuroinflammation. 2020;17:253 pubmed publisher
Hadisaputri Y, Cahyana N, Muchtaridi M, Lesmana R, Rusdiana T, Chaerunisa A, et al. Apoptosis-mediated antiproliferation of A549 lung cancer cells mediated by Eugenia aquea leaf compound 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone and its molecular interaction with caspase receptor in molecular docking simulation. Oncol Lett. 2020;19:3551-3557 pubmed publisher
Khan M, Shamma T, Kazmi S, Altuhami A, Ahmed H, Assiri A, et al. Hypoxia-induced complement dysregulation is associated with microvascular impairments in mouse tracheal transplants. J Transl Med. 2020;18:147 pubmed publisher
Kaihola H, Yaldir F, Bohlin T, Samir R, Hreinsson J, Akerud H. Levels of caspase-3 and histidine-rich glycoprotein in the embryo secretome as biomarkers of good-quality day-2 embryos and high-quality blastocysts. PLoS ONE. 2019;14:e0226419 pubmed publisher
Ma X, Cheng F, Yuan K, Jiang K, Zhu T. Lipid storage droplet protein 5 reduces sodium palmitate‑induced lipotoxicity in human normal liver cells by regulating lipid metabolism‑related factors. Mol Med Rep. 2019;20:879-886 pubmed publisher
O Brien C, Santos P, Kulikowicz E, Reyes M, Koehler R, Martin L, et al. Hypoxia-Ischemia and Hypothermia Independently and Interactively Affect Neuronal Pathology in Neonatal Piglets with Short-Term Recovery. Dev Neurosci. 2019;:1-17 pubmed publisher
Liu Z, Li H, He L, Xiang Y, Tian C, Li C, et al. Discovery of Small-Molecule Inhibitors of the HSP90-Calcineurin-NFAT Pathway against Glioblastoma. Cell Chem Biol. 2019;26:352-365.e7 pubmed publisher
Biernacki M, Łuczaj W, Jarocka Karpowicz I, Ambrożewicz E, Toczek M, Skrzydlewska E. The Effect of Long-Term Administration of Fatty Acid Amide Hydrolase Inhibitor URB597 on Oxidative Metabolism in the Heart of Rats with Primary and Secondary Hypertension. Molecules. 2018;23: pubmed publisher
Einsele Scholz S, Malmsheimer S, Bertram K, Stehle D, Johänning J, Manz M, et al. Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak. J Cell Sci. 2016;129:2213-23 pubmed publisher

product information

brand :

R&D Systems

master code :

AF-605-NA

SKU :

AF-605-NA

product name :

Human/Mouse Caspase-3 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse Caspase-3 Antibody from R&D Systems is a goat polyclonal antibody to Caspase-3. This antibody reacts with human,insect - drosophila melanogaster,mouse,rat. The Human/Mouse Caspase-3 Antibody has been validated for the following applications: Immunohistochemistry,Proximity Extension Assay,Western Blot,Immunocytochemistry,Immunoprecipitation,Simple Western,Knockout Validated.

target :

Caspase-3

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 0.5 ug/mL, Simple Western 5 ug/mL, Immunoprecipitation 1 ug/10^6 cells, Knockout Validated

host :

Goat

immunogen :

E. coli -derived recombinant human Caspase-3, Met1-His277, Accession # AAA65015

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Insect - Drosophila melanogaster,Mouse,Rat

specificity :

Detects human Caspase-3.

gene symbol :

CASP3

Antibody validation :

Knockout/Knockdown

top caption :

Detection of Human and Mouse Caspase-3 antibody by Western Blot.

accessionNumbers :

AAA65015

applications :

Immunoprecipitation,Simple Western,Knockout Validated,Proximity Extension Assay,Immunohistochemistry,Western Blot,Immunocytochemistry

USD :

509 USD

alt names :

Apopain, apoptosis-related cysteine protease, CASP3, CASP-3, caspase 3, apoptosis-related cysteine peptidase, caspase-3, Caspase3, CPP32, CPP-32, CPP32B, CPP32SREBP cleavage activity 1, Cysteine protease CPP32, EC 3.4.22, EC 3.4.22.56, LICE-1, PARP cleavage protease, procaspase3, Protein Yama, SCA-1, Yama

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage