Mouse Oncostatin M/OSM Antibody | R&D Systems AF-495-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse Oncostatin M/OSM Antibody

catalog :

AF-495-NA

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse, rat

application :

western blot, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 10

Reference
Yaghi O, Hanna B, Langston P, Michelson D, Jayewickreme T, Marin Rodero M, et al. A discrete 'early-responder' stromal-cell subtype orchestrates immunocyte recruitment to injured tissue. Nat Immunol. 2023;24:2053-2067 pubmed publisher
Wang Z, Yan B, Tang M, Jin D, Lai P. Tuberous sclerosis complex 1 targeted depletion in macrophages promotes osteogenesis by modulating secretion of Oncostatin M in the inflammatory stage of bone healing. Int Immunopharmacol. 2023;124:110895 pubmed publisher
Haensel D, Dániel B, Gaddam S, Pan C, Fabo T, Bjelajac J, et al. Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche. Nat Commun. 2023;14:2685 pubmed publisher
Song Y, Yang J, Li T, Sun X, Lin R, He Y, et al. CD34+ cell-derived fibroblast-macrophage cross-talk drives limb ischemia recovery through the OSM-ANGPTL signaling axis. Sci Adv. 2023;9:eadd2632 pubmed publisher
Komori T, Morikawa Y. Essential roles of the cytokine oncostatin M in crosstalk between muscle fibers and immune cells in skeletal muscle after aerobic exercise. J Biol Chem. 2022;298:102686 pubmed publisher
Buelow L, Hoji A, Tat K, Schroeder Carter L, Carroll D, Cook Mills J. Mechanisms for Alternaria alternata Function in the Skin During Induction of Peanut Allergy in Neonatal Mice With Skin Barrier Mutations. Front Allergy. 2021;2:677019 pubmed publisher
L xf6 rchner H, Adrian Segarra J, Waechter C, Wagner R, G xf3 es M, Brachmann N, et al. Concomitant Activation of OSM and LIF Receptor by a Dual-Specific hlOSM Variant Confers Cardioprotection after Myocardial Infarction in Mice. Int J Mol Sci. 2021;23: pubmed publisher
An S, Raju I, Surenkhuu B, Kwon J, Gulati S, Karaman M, et al. Neutrophil extracellular traps (NETs) contribute to pathological changes of ocular graft-vs.-host disease (oGVHD) dry eye: Implications for novel biomarkers and therapeutic strategies. Ocul Surf. 2019;: pubmed publisher
Liu Q, Du Y, Li K, Zhang W, Feng X, Hao J, et al. Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis. Mediators Inflamm. 2017;2017:3038514 pubmed publisher
Pohin M, Guesdon W, Mekouo A, Rabeony H, Paris I, Atanassov H, et al. Oncostatin M overexpression induces skin inflammation but is not required in the mouse model of imiquimod-induced psoriasis-like inflammation. Eur J Immunol. 2016;46:1737-51 pubmed publisher

product information

master code :

AF-495-NA

SKU :

AF-495-NA

product name :

Mouse Oncostatin M/OSM Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse Oncostatin M/OSM Antibody from R&D Systems is a goat polyclonal antibody to Oncostatin M/OSM. This antibody reacts with mouse,rat. The Mouse Oncostatin M/OSM Antibody has been validated for the following applications: In vivo assay,Neutralizing,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen.

target :

Oncostatin M/OSM

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse OSM, Ala24-Arg206, Accession # P53347

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse,Rat

specificity :

Detects mouse OSM in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant human OSM is observed.

gene symbol :

OSM

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Oncostatin M/OSM antibody in Mouse Embryo by Immunohistochemistry (IHC-Fr).

accessionNumbers :

P53347

applications :

In vivo assay,Neutralizing,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen

USD :

509 USD

alt names :

MGC20461, oncostatin M, oncostatin-M

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage