Mouse CCL7/MCP-3/MARC Antibody | R&D Systems AF-456-NA product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse CCL7/MCP-3/MARC Antibody

catalog :

AF-456-NA

quantity :

100 ug (also 25 ug)

price :

499 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

mouse

application :

western blot, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Reference
Takacs G, Kreiger C, Luo D, Tian G, Garcia J, Deleyrolle L, et al. Glioma-derived CCL2 and CCL7 mediate migration of immune suppressive CCR2+/CX3CR1+ M-MDSCs into the tumor microenvironment in a redundant manner. Front Immunol. 2022;13:993444 pubmed publisher
Komori T, Morikawa Y. Essential roles of the cytokine oncostatin M in crosstalk between muscle fibers and immune cells in skeletal muscle after aerobic exercise. J Biol Chem. 2022;298:102686 pubmed publisher
Kim H, Kim W, Shin H, Yoon H, Moon J, Lee E, et al. ROS-induced PADI2 downregulation accelerates cellular senescence via the stimulation of SASP production and NFκB activation. Cell Mol Life Sci. 2022;79:155 pubmed publisher
Xie C, Ye F, Zhang N, Huang Y, Pan Y, Xie X. CCL7 contributes to angiotensin II-induced abdominal aortic aneurysm by promoting macrophage infiltration and pro-inflammatory phenotype. J Cell Mol Med. 2021;25:7280-7293 pubmed publisher
Kurtz S, De Pascalis R, Meierovics A, Elkins K. Deficiency in CCR2 increases susceptibility of mice to infection with an intracellular pathogen, Francisella tularensis LVS, but does not impair development of protective immunity. PLoS ONE. 2021;16:e0249142 pubmed publisher
Bellomo A, Mondor I, Spinelli L, Lagueyrie M, Stewart B, Brouilly N, et al. Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages. Immunity. 2020;53:127-142.e7 pubmed publisher
Qi D, Wei M, Jiao S, Song Y, Wang X, Xie G, et al. Hypoxia inducible factor 1α in vascular smooth muscle cells promotes angiotensin II-induced vascular remodeling via activation of CCL7-mediated macrophage recruitment. Cell Death Dis. 2019;10:544 pubmed publisher
He J, Song Y, Li G, Xiao P, Liu Y, Xue Y, et al. Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation. J Clin Invest. 2019;129:3877-3893 pubmed publisher
Kwiatkowski K, Popiolek Barczyk K, Piotrowska A, Rojewska E, Ciapała K, Makuch W, et al. Chemokines CCL2 and CCL7, but not CCL12, play a significant role in the development of pain-related behavior and opioid-induced analgesia. Cytokine. 2019;119:202-213 pubmed publisher

product information

master code :

AF-456-NA

SKU :

AF-456-NA

product name :

Mouse CCL7/MCP-3/MARC Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse CCL7/MCP-3/MARC Antibody from R&D Systems is a goat polyclonal antibody to CCL7/MCP-3/MARC. This antibody reacts with mouse. The Mouse CCL7/MCP-3/MARC Antibody has been validated for the following applications: Bioassay,Flow Cytometry,Western Blot,Neutralization,In vivo assay.

target :

CCL7/MCP-3/MARC

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse CCL7/MCP-3/MARC, Gln24-Pro97, Accession # Q03366

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Mouse

specificity :

Detects mouse CCL7/MCP-3/MARC in direct ELISAs and Western blots. In direct ELISAs, approximately 15% cross-reactivity with recombinant human Eotaxin and recombinant mouse (rm) JE is observed and less than 5% cross-reactivity with rmMCP-5 is observed.

gene symbol :

CCL7

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Chemotaxis Induced by CCL7/MARC and Neutralization by Mouse CCL7/MARC Antibody.

accessionNumbers :

Q03366

applications :

Bioassay,Flow Cytometry,Western Blot,Neutralization,In vivo assay

USD :

499 USD

alt names :

C-C motif chemokine 7, chemokine (C-C motif) ligand 7, FIC, MARC, MCP-3, MCP3Monocyte chemotactic protein 3, MCP-3Small-inducible cytokine A7, MGC138465, Monocyte chemoattractant protein 3, NC28SCYA6, SCYA7MGC138463, small inducible cytokine A7 (monocyte chemotactic protein 3)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage