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company name :
R&D Systems
product type :
antibody
product name :
Mouse CXCL2/MIP-2 Antibody
catalog :
AF-452-NA
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 15
Reference
Chung K, Cheng C, Chen Y, Hsu C, Huang Y, Hsieh M, et al. Alveolar epithelial cells mitigate neutrophilic inflammation in lung injury through regulating mitochondrial fatty acid oxidation. Nat Commun. 2024;15:7241 pubmed publisher
B xe9 nard A, Mittelst xe4 dt A, Kl xf6 sch B, Glanz K, M xfc ller J, Schoen J, et al. IL-3 orchestrates ulcerative colitis pathogenesis by controlling the development and the recruitment of splenic reservoir neutrophils. Cell Rep. 2023;42:112637 pubmed publisher
Dong X, Zhang Q, Yu X, Wang D, Ma J, Ma J, et al. Metabolic lactate production coordinates vasculature development and progenitor behavior in the developing mouse neocortex. Nat Neurosci. 2022;: pubmed publisher
Mursalin M, Coburn P, Miller F, Livingston E, Astley R, Callegan M. C-X-C Chemokines Influence Intraocular Inflammation During Bacillus Endophthalmitis. Invest Ophthalmol Vis Sci. 2021;62:14 pubmed publisher
Urbantat R, Jelgersma C, Brandenburg S, Nieminen Kelhä M, Kremenetskaia I, Zollfrank J, et al. Tumor-Associated Microglia/Macrophages as a Predictor for Survival in Glioblastoma and Temozolomide-Induced Changes in CXCR2 Signaling with New Resistance Overcoming Strategy by Combination Therapy. Int J Mol Sci. 2021;22: pubmed publisher
Makino Y, Fujikawa K, Matsuki Fukushima M, Inoue S, Nakamura M. Role of Innate Inflammation in the Regulation of Tissue Remodeling during Tooth Eruption. Dent J (Basel). 2021;9: pubmed publisher
Song M, Chen L, Zhang L, Li C, Coffie J, Fang Z, et al. Cryptotanshinone enhances wound healing in type 2 diabetes with modulatory effects on inflammation, angiogenesis and extracellular matrix remodelling. Pharm Biol. 2020;58:845-853 pubmed publisher
Nakajima K, Ono M, Radović U, Dizdarevic S, Tomizawa S, Kuroha K, et al. Lack of whey acidic protein (WAP) four-disulfide core domain protease inhibitor 2 (WFDC2) causes neonatal death from respiratory failure in mice. Dis Model Mech. 2019;12: pubmed publisher
Hwang W, Lan H, Cheng W, Huang S, Yang M. Tumor stem-like cell-derived exosomal RNAs prime neutrophils for facilitating tumorigenesis of colon cancer. J Hematol Oncol. 2019;12:10 pubmed publisher
Zhou J, Li J, Yu Y, Liu Y, Li H, Liu Y, et al. Mannan-binding lectin deficiency exacerbates sterile liver injury in mice through enhancing hepatic neutrophil recruitment. J Leukoc Biol. 2019;105:177-186 pubmed publisher
Vikhe P, Purnell T, Brown S, Hood D. Cellular content plays a crucial role in Non-typeable Haemophilus influenzae infection of preinflamed Junbo mouse middle ear. Cell Microbiol. 2019;21:e12960 pubmed publisher
Stoolman J, Duncker P, Huber A, Giles D, Washnock Schmid J, Soulika A, et al. An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE. J Neuroinflammation. 2018;15:208 pubmed publisher
Tsubaki T, Kadonosono T, Sakurai S, Shiozawa T, Goto T, Sakai S, et al. Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment. Oncotarget. 2018;9:11209-11226 pubmed publisher
Inoue A, Matsumoto I, Tanaka Y, Umeda N, Takai C, Kawaguchi H, et al. TIARP attenuates autoantibody-mediated arthritis via the suppression of neutrophil migration by reducing CXCL2/CXCR2 and IL-6 expression. Sci Rep. 2016;6:38684 pubmed publisher
Boro M, Singh V, Balaji K. Mycobacterium tuberculosis-triggered Hippo pathway orchestrates CXCL1/2 expression to modulate host immune responses. Sci Rep. 2016;6:37695 pubmed publisher
product information
master code :
AF-452-NA
SKU :
AF-452-NA
product name :
Mouse CXCL2/MIP-2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse CXCL2/MIP-2 Antibody from R&D Systems is a goat polyclonal antibody to CXCL2/GRO beta/MIP-2/CINC-3. This antibody reacts with mouse,transgenic mouse. The Mouse CXCL2/MIP-2 Antibody has been validated for the following applications: Immunohistochemistry,Bioassay,Flow Cytometry,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry.
target :
CXCL2/GRO beta/MIP-2/CINC-3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant mouse CXCL2/MIP-2, Ala28-Asn100, Accession # P10889
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Transgenic Mouse
specificity :
Detects mouse CXCL2/MIP-2 in direct ELISAs and Western blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) GRO▀, recombinant mouse (rm) GRO gamma , rmKC and rmLIX is observed.
gene symbol :
CXCL2
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by CXCL2/MIP-2 and Neutral-ization by Mouse CXCL2/ MIP-2 Antibody.
accessionNumbers :
P10889
applications :
Immunohistochemistry,Bioassay,Flow Cytometry,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,In vivo assay,Immunocytochemistry
USD :
519 USD
alt names :
chemokine (C-X-C motif) ligand 2, CINC-2a, CINC3, CINC-3, C-X-C Motif Chemokine 2, GRO beta, GRO2, GRO2 oncogene, GROb, Gro-beta, Growth-regulated protein beta, Macrophage inflammatory protein 2-alpha, melanoma growth stimulatory activity beta, MGSA beta, MGSA-b, MGSA-beta, MIP2, MIP-2, MIP-2a, MIP2A, MIP2-alpha, SCYB2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.