product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CCL4/MIP-1▀ Antibody
catalog :
AF-451-NA
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section
more info or order :
R&D Systems product webpage
citations: 8
Reference
Gern B, Klas J, Foster K, Cohen S, Plumlee C, Duffy F, et al. CD4-mediated immunity shapes neutrophil-driven tuberculous pathology. bioRxiv. 2024;: pubmed publisher
Do Thi V, Park S, Park S, Jeong H, Cho G, An H, et al. IL9 Polarizes Macrophages to M1 and Induces the Infiltration of Antitumor Immune Cells via MIP-1 and CXCR3 Chemokines. Cancer Res Commun. 2023;3:80-96 pubmed publisher
Rosin J, Tretiakov N, Hanniman E, Hampton K, Kurrasch D. Gestational Bisphenol A Exposure Impacts Embryonic Hypothalamic Microglia Numbers, Ramification, and Phagocytic Cups. Front Neurosci. 2022;16:830399 pubmed publisher
Boutet M, Benet Z, Guillen E, Koch C, M Homa Soudja S, Delahaye F, et al. Memory CD8+ T cells mediate early pathogen-specific protection via localized delivery of chemokines and IFNγ to clusters of monocytes. Sci Adv. 2021;7:eabf9975 pubmed publisher
Osman A, Sun Y, Burns T, He L, Kee N, Oliva Vilarnau N, et al. Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain. Cell Rep. 2020;31:107699 pubmed publisher
Williford J, Ishihara J, Ishihara A, Mansurov A, Hosseinchi P, Marchell T, et al. Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy. Sci Adv. 2019;5:eaay1357 pubmed publisher
Hammond T, Dufort C, Dissing Olesen L, Giera S, Young A, Wysoker A, et al. Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes. Immunity. 2019;50:253-271.e6 pubmed publisher
Thaney V, O Neill A, Hoefer M, Maung R, Sanchez A, Kaul M. IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury. Sci Rep. 2017;7:46514 pubmed publisher
product information
master code :
AF-451-NA
SKU :
AF-451-NA
product name :
Mouse CCL4/MIP-1▀ Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse CCL4/MIP-1ß Antibody from R&D Systems is a goat polyclonal antibody to CCL4/MIP-1 beta. This antibody reacts with mouse,rat,transgenic mouse. The Mouse CCL4/MIP-1ß Antibody has been validated for the following applications: Immunohistochemistry,Flow Cytometry,Neutralization,ELISA Development,Immunohistochemistry-Paraffin,Immunocytochemistry,Western Blot.
target :
CCL4/MIP-1 beta
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
E. coli -derived recombinant mouse CCL4/MIP-1▀, Ala24-Asn92, Accession # Q5QNV9
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Rat,Transgenic Mouse
specificity :
Detects CCL4/MIP-1▀ in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human (rh) MIP-1▀ and recombinant mouse (rm) MIP-1 alpha is observed. This antibody will not neutralize the biological activity of rmMIP-1 alpha . In the chemotaxis assay this antibody will partially neutralize rhMIP-1 alpha and rhMIP-1▀ at a 10-30 fold higher IgG concentration.
gene symbol :
CCL4
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Mouse CCL4/MIP-1ss antibody by Western Blot.
accessionNumbers :
Q5QNV9
applications :
Flow Cytometry,Immunohistochemistry,Neutralization,ELISA Development,Immunohistochemistry-Paraffin,Immunocytochemistry,Western Blot
USD :
519 USD
alt names :
ACT2, ACT-2, AT744.1, C-C motif chemokine 4, chemokine (C-C motif) ligand 4, Exodus-3, G-26, G-26 T-lymphocyte-secreted protein, HC21, LAG1, LAG-1, Lymphocyte activation gene 1 protein, Macrophage inflammatory protein 1-beta, MIP1 beta, MIP-1 beta, MIP1B, MIP1B1, MIP-1-beta, MIP-1-beta(1-69), PAT 744, Protein H400, SCYA2, SCYA4, secreted protein G-26, SIS-gamma, small inducible cytokine A4 (homologous to mouse Mip-1b), Small-inducible cytokine A4, T-cell activation protein 2
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.