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company name :
R&D Systems
product type :
antibody
product name :
Mouse CCL3/MIP-1 alpha Antibody
catalog :
AF-450-NA
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 13
Reference
Ciechanowska A, Pawlik K, Ciapa x142 a K, Mika J. Pharmacological Modulation of the MIP-1 Family and Their Receptors Reduces Neuropathic Pain Symptoms and Influences Morphine Analgesia: Evidence from a Mouse Model. Brain Sci. 2023;13: pubmed publisher
Do Thi V, Park S, Park S, Jeong H, Cho G, An H, et al. IL9 Polarizes Macrophages to M1 and Induces the Infiltration of Antitumor Immune Cells via MIP-1 and CXCR3 Chemokines. Cancer Res Commun. 2023;3:80-96 pubmed publisher
Yuan X, Xiong Z, Liu W, Li Y, Li H, Zhang X, et al. Novel Therapeutic Targeting of CCL3-CCR4 Axis Mediated Apoptotic Intesitnal Injury in Necrotizing Enterocolitis. Front Immunol. 2022;13:859398 pubmed publisher
Rosin J, Tretiakov N, Hanniman E, Hampton K, Kurrasch D. Gestational Bisphenol A Exposure Impacts Embryonic Hypothalamic Microglia Numbers, Ramification, and Phagocytic Cups. Front Neurosci. 2022;16:830399 pubmed publisher
Bhattacharya P, Ismail N, Saxena A, Gannavaram S, Dey R, Oljuskin T, et al. Neutrophil-dendritic cell interaction plays an important role in live attenuated Leishmania vaccine induced immunity. PLoS Negl Trop Dis. 2022;16:e0010224 pubmed publisher
Boutet M, Benet Z, Guillen E, Koch C, M Homa Soudja S, Delahaye F, et al. Memory CD8+ T cells mediate early pathogen-specific protection via localized delivery of chemokines and IFNγ to clusters of monocytes. Sci Adv. 2021;7:eabf9975 pubmed publisher
Galeano Niño J, Pageon S, Tay S, Colakoglu F, Kempe D, Hywood J, et al. Cytotoxic T cells swarm by homotypic chemokine signalling. elife. 2020;9: pubmed publisher
Osman A, Sun Y, Burns T, He L, Kee N, Oliva Vilarnau N, et al. Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain. Cell Rep. 2020;31:107699 pubmed publisher
Pajer K, Bellák T, Redl H, Nogradi A. Neuroectodermal stem cells grafted into the injured spinal cord induce both axonal regeneration and morphological restoration via multiple mechanisms. J Neurotrauma. 2019;: pubmed publisher
John B, Naczki C, Patel C, Ghoneum A, Qasem S, Salih Z, et al. Regulation of the bi-directional cross-talk between ovarian cancer cells and adipocytes by SPARC. Oncogene. 2019;38:4366-4383 pubmed publisher
Sun W, Meednu N, Rosenberg A, Rangel Moreno J, Wang V, Glanzman J, et al. B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation. Nat Commun. 2018;9:5127 pubmed publisher
Thaney V, O Neill A, Hoefer M, Maung R, Sanchez A, Kaul M. IFNβ Protects Neurons from Damage in a Murine Model of HIV-1 Associated Brain Injury. Sci Rep. 2017;7:46514 pubmed publisher
Laurent C, Dorothee G, Hunot S, Martin E, Monnet Y, Duchamp M, et al. Hippocampal T cell infiltration promotes neuroinflammation and cognitive decline in a mouse model of tauopathy. Brain. 2017;140:184-200 pubmed publisher
product information
brand :
R&D Systems
master code :
AF-450-NA
SKU :
AF-450-NA
product name :
Mouse CCL3/MIP-1 alpha Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse CCL3/MIP-1 alpha Antibody from R&D Systems is a goat polyclonal antibody to CCL3/MIP-1 alpha. This antibody reacts with mouse,rat. The Mouse CCL3/MIP-1 alpha Antibody has been validated for the following applications: In vivo assay,Neutralization,ELISA Development,ELISpot Development,Luminex Development,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunocytochemistry,Western Blot,ELISA Capture (Matched Antibody Pair).
target :
CCL3/MIP-1 alpha
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 0.05-0.2 ug/mL, Immunocytochemistry 5-15 ug/mL, ELISA Capture (Matched Antibody Pair) 0.2-0.8 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant mouse CCL3/MIP-1 alpha , Ala24-Ala92, Accession # Q5QNW0
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse,Rat
specificity :
Detects mouse CCL3/MIP-1 alpha in ELISAs and Western blots. In sandwich ELISAs, less than 0.03% cross-reactivity with recombinant human (rh) CCL3, recombinant mouse (rm) CCL9/10, and rmCCL4 and less than 0.4% cross-reactivity with rhCCL7.
gene symbol :
CCL3
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Mouse CCL3/MIP-1a antibody by Western Blot.
accessionNumbers :
Q5QNW0
applications :
Western Blot,ELISA Capture (Matched Antibody Pair),ELISA Development,ELISpot Development,Luminex Development,Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin,In vivo assay,Neutralization,Immunocytochemistry
USD :
519 USD
alt names :
C-C motif chemokine 3, MIP1-(a), AI323804, chemokine (C-C motif) ligand 3, G0S19-1, LD78a, LD78alpha, MIP1 alpha, MIP-1 alpha, Mip1a, MIP-1alpha, MIP1-alpha, PAT 464.1, SCYA3, SIS-beta
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.