Mouse TNF RI/TNFRSF1A Antibody | R&D Systems AF-425-PB product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse TNF RI/TNFRSF1A Antibody

catalog :

AF-425-PB

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunoprecipitation; mouse; loading ...; fig 3a	Meng H, Liu Z, Li X, Wang H, Jin T, Wu G, et al. Death-domain dimerization-mediated activation of RIPK1 controls necroptosis and RIPK1-dependent apoptosis. Proc Natl Acad Sci U S A. 2018;115:E2001-E2009 pubmed publisher
	Huynh P, Hoffmann J, Gerhardt T, Kiss M, Zuraikat F, Cohen O, et al. Myocardial infarction augments sleep to limit cardiac inflammation and damage. Nature. 2024;635:168-177 pubmed publisher
	Renz P, Ghoshdastider U, Baghai Sain S, Valdivia Francia F, Khandekar A, Ormiston M, et al. In vivo single-cell CRISPR uncovers distinct TNF programmes in tumour evolution. Nature. 2024;632:419-428 pubmed publisher
	Knizkova D, Pribikova M, Draberova H, Semberova T, Trivic T, Synackova A, et al. CMTM4 is a subunit of the IL-17 receptor and mediates autoimmune pathology. Nat Immunol. 2022;23:1644-1652 pubmed publisher
	Wu G, Li D, Liang W, Sun W, Xie X, Tong Y, et al. PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIPL to promote TNFα-mediated cell death. Cell Death Dis. 2022;13:773 pubmed publisher
	Akagi T, Hiramatsu Asano S, Ikeda K, Hirano H, Tsuji S, Yahagi A, et al. TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1. Front Immunol. 2022;13:926175 pubmed publisher
	Yin H, Guo X, Chen Y, Zeng Y, Mo X, Hong S, et al. TAB2 deficiency induces dilated cardiomyopathy by promoting RIPK1-dependent apoptosis and necroptosis. J Clin Invest. 2022;132: pubmed publisher
	Won M, Park K, Kim S, Ju E, Ko Y, Yoo H, et al. ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-κB. Cell Death Differ. 2022;29:1152-1163 pubmed publisher
	Polykratis A, Martens A, Eren R, Shirasaki Y, Yamagishi M, Yamaguchi Y, et al. A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain. Nat Cell Biol. 2019;21:731-742 pubmed publisher
	Wu Z, Geng Y, Lu X, Shi Y, Wu G, Zhang M, et al. Chaperone-mediated autophagy is involved in the execution of ferroptosis. Proc Natl Acad Sci U S A. 2019;116:2996-3005 pubmed publisher
	Martens S, Jeong M, Tonnus W, Feldmann F, Hofmans S, Goossens V, et al. Sorafenib tosylate inhibits directly necrosome complex formation and protects in mouse models of inflammation and tissue injury. Cell Death Dis. 2017;8:e2904 pubmed publisher
	Arokiasamy S, Zakian C, Dilliway J, Wang W, Nourshargh S, Voisin M. Endogenous TNFα orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation. Sci Rep. 2017;7:44189 pubmed publisher

product information

master code :

AF-425-PB

SKU :

AF-425-PB

product name :

Mouse TNF RI/TNFRSF1A Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse TNF RI/TNFRSF1A Antibody from R&D Systems is a goat polyclonal antibody to TNF RI/TNFRSF1A. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse TNF RI/TNFRSF1A Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Immunohistochemistry,Complex Application,ELISA Development,IP Western,Immunoprecipitation,Immunohistochemistry-Frozen,Immunocytochemistry,Agonist Activity,CyTOF-ready.

target :

TNF RI/TNFRSF1A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

E. coli -derived recombinant mouse TNF RI, Ile22-Ala212, Accession # P25118

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Mouse,Rat,Transgenic Mouse

specificity :

Detects mouse TNF RI/TNFRSF1A in direct ELISAs and Western blots. In direct ELISAs and Western blots (non-reducing conditions), less than 5% cross-reactivity with recombinant human TNF RI is observed.

gene symbol :

TNFRSF1A

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Mouse TNF RI/TNFRSF1A antibody by Western Blot.

accessionNumbers :

P25118

applications :

Flow Cytometry,Immunohistochemistry,Complex Application,ELISA Development,IP Western,Immunoprecipitation,Western Blot,Immunohistochemistry-Frozen,Immunocytochemistry,Agonist Activity,CyTOF-ready

USD :

509 USD

alt names :

CD120a, CD120a antigen, FPF, p55, p55-R, p60, TNFARMGC19588, TNF-R, TNF-R1, TNFR1TBP1, TNFR55, TNF-R55, TNFR60, TNFRI, TNF-RI, TNF-R-I, TNFR-I, TNFRSF1A, tumor necrosis factor binding protein 1, Tumor necrosis factor receptor 1, tumor necrosis factor receptor 1A isoform beta, tumor necrosis factor receptor superfamily member 1A, tumor necrosis factor receptor superfamily, member 1A, tumor necrosis factor receptor type 1, Tumor necrosis factor receptor type I, tumor necrosis factor-alpha receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage