product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CCL11/Eotaxin Antibody
catalog :
AF-420-NA
quantity :
100 ug (also 25 ug)
price :
519 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
R&D Systems product webpage
citations: 6
Reference
Cosway E, White A, Parnell S, Schweighoffer E, Jolin H, Bacon A, et al. Eosinophils are an essential element of a type 2 immune axis that controls thymus regeneration. Sci Immunol. 2022;7:eabn3286 pubmed publisher
Choi H, Won T, Hou X, Chen G, Bracamonte Baran W, Talor M, et al. Innate Lymphoid Cells Play a Pathogenic Role in Pericarditis. Cell Rep. 2020;30:2989-3003.e6 pubmed publisher
Boström M, Kalm M, Eriksson Y, Bull C, Ståhlberg A, Bjork Eriksson T, et al. A role for endothelial cells in radiation-induced inflammation. Int J Radiat Biol. 2018;94:259-271 pubmed publisher
Henschel A, Cabrera S, Kaldunski M, Jia S, Geoffrey R, Roethle M, et al. Modulation of the diet and gastrointestinal microbiota normalizes systemic inflammation and β-cell chemokine expression associated with autoimmune diabetes susceptibility. PLoS ONE. 2018;13:e0190351 pubmed publisher
Kindstedt E, Holm C, Sulniute R, Martinez Carrasco I, Lundmark R, Lundberg P. CCL11, a novel mediator of inflammatory bone resorption. Sci Rep. 2017;7:5334 pubmed publisher
Diny N, Hou X, Barin J, Chen G, Talor M, Schaub J, et al. Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart. Eur J Immunol. 2016;46:2749-2760 pubmed publisher
product information
brand :
R&D Systems
master code :
AF-420-NA
SKU :
AF-420-NA
product name :
Mouse CCL11/Eotaxin Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Mouse CCL11/Eotaxin Antibody from R&D Systems is a goat polyclonal antibody to CCL11/Eotaxin. This antibody reacts with human,mouse,rat. The Mouse CCL11/Eotaxin Antibody has been validated for the following applications: ELISA Development,Luminex Development,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,ELISA Capture (Matched Antibody Pair).
target :
CCL11/Eotaxin
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 0.1-0.5 ug/mL, ELISA Capture (Matched Antibody Pair) 0.2-0.8 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant mouse CCL11/Eotaxin, His24-Pro97, Accession # P48298
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human,Mouse,Rat
specificity :
Detects mouse CCL11/Eotaxin in ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human CCL11/Eotaxin is observed, and less than 5% cross-reactivity with recombinant mouse JE is observed.
gene symbol :
CCL11
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Chemotaxis Induced by CCL11/Eotaxin and Neutral-ization by Mouse CCL11/ Eotaxin Antibody.
accessionNumbers :
P48298
applications :
ELISA Capture (Matched Antibody Pair),ELISA Development,Luminex Development,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization
USD :
519 USD
alt names :
C-C motif chemokine 11, chemokine (C-C motif) ligand 11, Eosinophil chemotactic protein, Eotaxin, eotaxin-1, MGC22554, SCYA11Small-inducible cytokine A11, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.