product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse IL-12 Antibody
catalog :
AF-419-NA
quantity :
100 ug (also 25 ug)
price :
549 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
mouse
application :
western blot, neutralization
more info or order :
citations: 6
Reference
Zhong X, Wu H, Zhang W, Shi Y, Gwack Y, Xue H, et al. Distinct RORγt-dependent Th17 immune responses are required for autoimmune pathogenesis and protection against bacterial infection. Cell Rep. 2024;43:114951 pubmed publisher
Blanco T, Nakagawa H, Musayeva A, Krauthammer M, Singh R, Narimatsu A, et al. Acquired immunostimulatory phenotype of migratory CD103+ DCs promotes alloimmunity following corneal transplantation. JCI Insight. 2024;9: pubmed publisher
Tesfaye D, Bobic S, Lys xe9 n A, Huszthy P, Gudjonsson A, Braathen R, et al. Targeting Xcr1 on Dendritic Cells Rapidly Induce Th1-Associated Immune Responses That Contribute to Protection Against Influenza Infection. Front Immunol. 2022;13:752714 pubmed publisher
Sun L, Kees T, Almeida A, Liu B, He X, Ng D, et al. Activating a collaborative innate-adaptive immune response to control metastasis. Cancer Cell. 2021;39:1361-1374.e9 pubmed publisher
Gao K, Jin J, Huang C, Li J, Luo H, Li L, et al. Exosomes Derived From Septic Mouse Serum Modulate Immune Responses via Exosome-Associated Cytokines. Front Immunol. 2019;10:1560 pubmed publisher
Lei W, Zeng D, Liu G, Zhu Y, Wang J, Wu H, et al. Crucial role of OX40/OX40L signaling in a murine model of asthma. Mol Med Rep. 2018;17:4213-4220 pubmed publisher
product information
master code :
AF-419-NA
SKU :
AF-419-NA
product name :
Mouse IL-12 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse IL-12 Antibody from R&D Systems is a goat polyclonal antibody to IL-12. This antibody reacts with mouse. The Mouse IL-12 Antibody has been validated for the following applications: Neutralization,Bioassay,Western Blot,Functional Assay.
target :
IL-12
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
host :
Goat
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse IL-12, Mouse IL-12 heterodimer: Mouse IL-12 p40 (Met23-Ser335) Accession # P43432, Mouse IL-12 p35 (Arg23-Ala215) Accession # NP_032377
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Mouse
specificity :
Detects mouse IL-12 in direct ELISAs and Western blots. In direct ELISAs and Western blots (non-reducing and reducing conditions), this antibody shows less than 10% cross-reactivity with recombinant human IL-12.
gene symbol :
IL12A
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by IL-12 and Neutralization by Mouse IL-12 Antibody.
applications :
Neutralization,Bioassay,Western Blot,Functional Assay
USD :
549 USD
alt names :
CLMF p35, CLMF1, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL12, IL-12 subunit p35, IL-12, subunit p35, IL12A, interleukin 12, p35, interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocytematuration factor 1, p35), interleukin-12 alpha chain, interleukin-12 subunit alpha, natural killer cell stimulatory factor 1, 35 kD subunit, NF cell stimulatory factor chain 1, NK cell stimulatory factor chain 1, NKSF1, p35
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.