product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human NRG1┐▀1/HRG1┐▀1 EGF Domain Antibody
catalog :
AF-396-NA
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
polyclonal
host :
domestic goat
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, neutralization
more info or order :
R&D Systems product webpage
citations: 2
Reference
Kundumani Sridharan V, Subramani J, Owens C, Das K. Nrg1β Released in Remote Ischemic Preconditioning Improves Myocardial Perfusion and Decreases Ischemia/Reperfusion Injury via ErbB2-Mediated Rescue of Endothelial Nitric Oxide Synthase and Abrogation of Trx2 Autophagy. Arterioscler Thromb Vasc Biol. 2021;41:2293-2314 pubmed publisher
Liao H, Zhang C, Chen Z, Gao Y, Li Z, Wang L, et al. CAN017, a novel anti-HER3 antibody, exerted great potency in mouse avatars of esophageal squamous cell carcinoma with NRG1 as a biomarker. Am J Cancer Res. 2021;11:1697-1708 pubmed
product information
brand :
R&D Systems
master code :
AF-396-NA
SKU :
AF-396-NA
product name :
Human NRG1┐▀1/HRG1┐▀1 EGF Domain Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human NRG1¿ß1/HRG1¿ß1 EGF Domain Antibody from R&D Systems is a goat polyclonal antibody to Neuregulin-1 beta 1/NRG1 beta 1. This antibody reacts with human. The Human NRG1¿ß1/HRG1¿ß1 EGF Domain Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Neutralization.
target :
Neuregulin-1 beta 1/NRG1 beta 1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Polyclonal
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 0.1 ug/mL, Immunohistochemistry 5-15 ug/mL, Neutralization 0.5-2.0 ug/mL
host :
Goat
immunogen :
E. coli -derived recombinant human NRG1┐▀1/HRG1┐▀1 EGF Domain, Thr176-Lys246, Accession # NP_039250
isotype :
IgG
purity :
Antigen Affinity-purified
species :
Human
specificity :
Detects human NRG1┐▀1/HRG1┐▀1 EGF Domain in direct ELISAs and Western blots. In Western blots (reducing conditions), approximately 100% cross-reactivity with recombinant human HRG-alpha is observed. In direct ELISAs, approximately 5% cross-reactivity with recombinant human HRG-alpha is observed.
gene symbol :
NRG1
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by NRG1-ss1/HRG1-ss1 and Neutralization by Human NRG1-ss1/HRG1-ss1 Antibody.
accessionNumbers :
NP_039250
applications :
Neutralization,Immunohistochemistry,Western Blot
USD :
509 USD
alt names :
ARIA, GGF, GGF2, Heregulin-1, HGL, HRG, HRG1, HRG1-alpha, HRG1-beta 1, HRGA, MST131, MSTP131, NDF, neuregulin 1, Neuregulin1, Neuregulin1 beta 1, NRG1, NRG1-IT2, SMDF
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.