Human CTLA-4 Antibody | R&D Systems AF-386-PB product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CTLA-4 Antibody

catalog :

AF-386-PB

quantity :

100 ug (also 25 ug)

price :

509 USD

clonality :

polyclonal

host :

domestic goat

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Oliveira A, de Souza C, Ramos Sanchez E, Diniz S, de Souza Lima E, Blagitz M, et al. Periparturient blood T-lymphocyte PD-1 and CTLA-4 expression as potential predictors of new intramammary infections in dairy cows during early lactation (short communication). BMC Vet Res. 2024;20:146 pubmed publisher
de Souza C, Lima E, Ordonho R, Oliveira B, Rodrigues R, de Moura M, et al. Brief Research Report: Expression of PD-1 and CTLA-4 in T Lymphocytes and Their Relationship With the Periparturient Period and the Endometrial Cytology of Dairy Cows During the Postpartum Period. Front Vet Sci. 2022;9:928521 pubmed publisher
Russick J, Joubert P, Gillard Bocquet M, Torset C, Meylan M, Petitprez F, et al. Natural killer cells in the human lung tumor microenvironment display immune inhibitory functions. J Immunother Cancer. 2020;8: pubmed publisher
Brown C, Sekhavati F, Cardenes R, Windmueller C, Dacosta K, Rodriguez Canales J, et al. CTLA-4 Immunohistochemistry and Quantitative Image Analysis for Profiling of Human Cancers. J Histochem Cytochem. 2019;:22155419882292 pubmed publisher
Ehlerding E, Lee H, Jiang D, Ferreira C, Zahm C, Huang P, et al. Antibody and fragment-based PET imaging of CTLA-4+ T-cells in humanized mouse models. Am J Cancer Res. 2019;9:53-63 pubmed
Jiang L, Su X, Zhang T, Yin X, Zhang M, Fu H, et al. PD-L1 expression and its relationship with oncogenic drivers in non-small cell lung cancer (NSCLC). Oncotarget. 2017;8:26845-26857 pubmed publisher

product information

master code :

AF-386-PB

SKU :

AF-386-PB

product name :

Human CTLA-4 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human CTLA-4 Antibody from R&D Systems is a goat polyclonal antibody to CTLA-4. This antibody reacts with human,xenograft. The Human CTLA-4 Antibody has been validated for the following applications: Immunohistochemistry,Flow Ctyometry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow Cytometry,Western Blot,Immunocytochemistry,CyTOF-ready.

target :

CTLA-4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Polyclonal

concentration :

LYOPH

conjugate :

Unconjugated

host :

Goat

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CTLA-4, Ala37-Phe162, Accession # Q6GR94

isotype :

IgG

purity :

Antigen Affinity-purified

species :

Human,Xenograft

specificity :

Detects human CTLA-4 in direct ELISAs and Western blots. In Western blots, approximately 25% cross-reactivity with recombinant mouse CTLA-4 is observed.

gene symbol :

CTLA4

top caption :

Detection of Human CTLA-4 antibody by Western Blot.

accessionNumbers :

Q6GR94

applications :

Flow Ctyometry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Flow Cytometry,Western Blot,Immunocytochemistry,CyTOF-ready

USD :

509 USD

alt names :

CD, CD152, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA4, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage